Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Oltvai, Z. N."'
Publikováno v:
PLoS Comput Biol 1, e68 (2005)
Understanding the system level adaptive changes taking place in an organism in response to variations in the environment is a key issue of contemporary biology. Current modeling approaches such as the constraint-based flux balance analyses (FBA) have
Externí odkaz:
http://arxiv.org/abs/q-bio/0601041
Publikováno v:
PNAS 101, 17945 (2004)
Recent evidence indicates that the abundance of recurring elementary interaction patterns in complex networks, often called subgraphs or motifs, carry significant information about their function and overall organization. Yet, the underlying reasons
Externí odkaz:
http://arxiv.org/abs/cond-mat/0408431
Publikováno v:
Nature 427, 839-843 (2004)
Cellular metabolism, the integrated interconversion of thousands of metabolic substrates through enzyme-catalyzed biochemical reactions, is the most investigated complex intercellular web of molecular interactions. While the topological organization
Externí odkaz:
http://arxiv.org/abs/q-bio/0403001
Publikováno v:
Nature Genetics, 35(2), 176-179, (2003)
Understanding why some cellular components are conserved across species, while others evolve rapidly is a key question of modern biology. Here we demonstrate that in S. cerevisiae proteins organized in cohesive patterns of interactions are conserved
Externí odkaz:
http://arxiv.org/abs/q-bio/0310024
Autor:
Farkas, I., Derenyi, I., Jeong, H., Neda, Z., Oltvai, Z. N., Ravasz, E., Schubert, A., Barabasi, A. -L., Vicsek, T.
Publikováno v:
Physica A 314 (2002) 25-34
We analyse growing networks ranging from collaboration graphs of scientists to the network of similarities defined among the various transcriptional profiles of living cells. For the explicit demonstration of the scale-free nature and hierarchical or
Externí odkaz:
http://arxiv.org/abs/cond-mat/0303106
Publikováno v:
Science 297 (2002), pp. 1551-1555
Spatially or chemically isolated functional modules composed of several cellular components and carrying discrete functions are considered fundamental building blocks of cellular organization, but their presence in highly integrated biochemical netwo
Externí odkaz:
http://arxiv.org/abs/cond-mat/0209244
Publikováno v:
Physica A, vol. 318/3-4 (2003) pp. 601-612
MOTIVATION: A central goal of postgenomic biology is the elucidation of the regulatory relationships among all cellular constituents that together comprise the 'genetic network' of a cell or microorganism. Experimental manipulation of gene activity c
Externí odkaz:
http://arxiv.org/abs/cond-mat/0205181
Publikováno v:
Nature Genetics vol. 29 54-56 (2001)
A central and long-standing issue in evolutionary theory is the origin of the biological variation upon which natural selection acts1. Some hypotheses suggest that evolutionary change represents an adaptation to the surrounding environment within the
Externí odkaz:
http://arxiv.org/abs/cond-mat/0110370
Publikováno v:
Nature, v407 651-654 (2000)
In a cell or microorganism the processes that generate mass, energy, information transfer, and cell fate specification are seamlessly integrated through a complex network of various cellular constituents and reactions. However, despite the key role t
Externí odkaz:
http://arxiv.org/abs/cond-mat/0010278
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2005 May . 102(22), 7841-7846.
Externí odkaz:
https://www.jstor.org/stable/3375681
