Supplementary Figure from Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma

Autor: Sergey I. Nikolaev, Nicole Basset-Seguin, Lukas Flatz, Nicolas Dumaz, Frederic J. de Sauvage, Jerome Lambert, Florian Herms, Philippe Saiag, Caroline Robert, Caroline Dutriaux, Nicolas Meyer, Laurent Mortier, Sandrine Monestier, Florent Grange, Max Mendez-Lopez, Andrej Besse, Ariel Savina, Fanny Bouquet, Samia Mourah, Maxime Battistella, Nadem Soufir, Antonio Alberti, Marc Delord, Amir Khammari, Brigitte Dreno, Nicolas Poulalhon, Hayley J. Sharpe, Fatemeh Rajabi, Ismael Padioleau, Meriem Ighilahriz, Oltin T. Pop, Andrey A. Yurchenko

Supplementary Figure from Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351f6102c14b7c4e17ca3b39ea656edf
https://doi.org/10.1158/1078-0432.22487462.v1

Frequency and Genomic Aspects of Intrinsic Resistance to Vismodegib in Locally Advanced Basal Cell Carcinoma

Autor: Andrey A. Yurchenko, Oltin T. Pop, Meriem Ighilahriz, Ismael Padioleau, Fatemeh Rajabi, Hayley J. Sharpe, Nicolas Poulalhon, Brigitte Dreno, Amir Khammari, Marc Delord, Antonio Alberti, Nadem Soufir, Maxime Battistella, Samia Mourah, Fanny Bouquet, Ariel Savina, Andrej Besse, Max Mendez-Lopez, Florent Grange, Sandrine Monestier, Laurent Mortier, Nicolas Meyer, Caroline Dutriaux, Caroline Robert, Philippe Saiag, Florian Herms, Jerome Lambert, Frederic J. de Sauvage, Nicolas Dumaz, Lukas Flatz, Nicole Basset-Seguin, Sergey I. Nikolaev

Publikováno v: Clinical Cancer Research
Clinical Cancer Research, 2022, pp.clincanres.3764.2021. ⟨10.1158/1078-0432.CCR-21-3764⟩

Purpose: Vismodegib is approved for the treatment of locally advanced basal cell carcinoma (laBCC), but some cases demonstrate intrinsic resistance (IR) to the drug. We sought to assess the frequency of IR to vismodegib in laBCC and its underlying ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1499e614bc9925511cb91b87a6471f26
https://doi.org/10.1158/1078-0432.ccr-21-3764

CD8+T cells from patients with cirrhosis display a phenotype that may contribute to cirrhosis-associated immune dysfunction

Autor: Sujit Mukherjee, Evangelos Triantafyllou, Oltin T Pop, Fabien Zoulim, Enes Tunc, Alberto Quaglia, Arjuna Singanayagam, Wafa Khamri, Mark Thursz, Tie Zheng Hou, Fanny Lebossé, Julia Wendon, Rooshi Nathwani, Charalambos G. Antoniades, Cathrin Gudd, Naveenta Kumar, A. Dhar

Publikováno v: EBioMedicine
EBioMedicine, 2019, 49, pp.258-268. ⟨10.1016/j.ebiom.2019.10.011⟩

Background Cirrhosis-associated immune dysfunction (CAID) contributes to high sepsis risk in patients with chronic liver disease. Various innate and; to a lesser extent; adaptive immune dysfunctions have been described as contributors to CAID leading

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9318081e284f95b31ce34f205764d8db
http://europepmc.org/articles/PMC6945243

IgA autoantibodies target pulmonary surfactant in patients with severe COVID-19

Autor: Pietro Vernazza, Lorenz Risch, Silvio D. Brugger, Omar Ali, Mara Gilardi, Martin Brutsche, Tobias Sinnberg, Lukas Flatz, Marie-Therese Abdou, Ana Velic, Alexandar Tzankov, David Bomze, Hubert Kalbacher, Oltin T Pop, Carl Zinner, Martin Roecken, Philipp Kohler, Matthias S. Matter, Josef M Penninger, Christian R Kahlert, Christa Lichtensteiger, Lukas Kern, Boris Macek, Werner C. Albrich

Complications affecting the lung are hallmarks of severe coronavirus disease 2019 (COVID-19). While there is evidence for autoimmunity in severe COVID-19, the exact mechanisms remain unknown. Here, we established a prospective observational cohort to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a530a034e118423364d0b39f31b791f6
https://doi.org/10.1101/2021.02.02.21250940

Normothermic machine perfusion (NMP) inhibits proinflammatory responses in the liver and promotes regeneration

Autor: Yasmeen G. Ghnewa, Emmanuel Xystrakis, Muhammed Yuksel, X. Huang, Juan José Lozano, Mohamed Rela, Wayel Jassem, Peter J. Friend, Marc Martinez-Llordella, Yun Ma, Nigel Heaton, Oltin T Pop, Alberto Sanchez-Fueyo, Alberto Quaglia, Constantin C. Coussios, Yamen Jabri

Publikováno v: Jassem, W, Xystrakis, E, Ghnewa, Y G, Yuksel, M, Pop, O, Martinez-Llordella, M, Jabri, Y, Huang, X, Lozano, J J, Quaglia, A, Sanchez-Fueyo, A, Coussios, C C, Rela, M, Friend, P, Heaton, N & Ma, Y 2019, ' Normothermic Machine Perfusion (NMP) Inhibits Proinflammatory Responses in the Liver and Promotes Regeneration ', Hepatology, vol. 70, no. 2, pp. 682-695 . https://doi.org/10.1002/hep.30475

Liver transplantation (LT) is a successful treatment for patients with liver failure. However, organ shortage results in over 11% of patients losing their chance of a transplant attributed to liver decompensation (LD) and death. Ischemia/reperfusion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0ef47dfd4d2c2bd5090f0387d6440b2
http://ora.ox.ac.uk/objects/uuid: