Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria

Autor: Lennartz, Frank, Adams, Yvonne, Bengtsson, Anja, Olsen, Rebecca W., Turner, Louise, Ndam, Nicaise T., Ecklu-Mensah, Gertrude, Moussiliou, Azizath, Ofori, Michael F., Gamain, Benoit, Lusingu, John P., Petersen, Jens E.V., Wang, Christian W., Nunes-Silva, Sofia, Jespersen, Jakob S., Lau, Clinton K.Y., Theander, Thor G., Lavstsen, Thomas, Hviid, Lars, Higgins, Matthew K., Jensen, Anja T.R.

Publikováno v: In Cell Host & Microbe 8 March 2017 21(3):403-414

Blood outgrowth endothelial cells (BOECs) as a novel tool for studying adhesion of Plasmodium falciparum-infected erythrocytes.

Autor: Ecklu-Mensah, Gertrude^1,2, Olsen, Rebecca W.², Bengtsson, Anja², Ofori, Michael F.¹, Hviid, Lars^2,3, Jensen, Anja T. R.², Adams, Yvonne² yadams@sund.ku.dk

Publikováno v: PLoS ONE. 10/9/2018, Vol. 13 Issue 10, p1-12. 12p.

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Mapping the binding site of a cross-reactive Plasmodium falciparum PfEMP1 monoclonal antibody inhibitory of ICAM-1 binding

Autor: Lennartz, Frank, Bengtsson, Anja, Olsen, Rebecca W, Joergensen, Louise, Brown, Alan, Remy, Louise, Man, Petr, Forest, Eric, Barfod, Lea K, Adams, Yvonne, Higgins, Matthew K, Jensen, Anja T R

Publikováno v: Lennartz, F, Bengtsson, A, Olsen, R W, Joergensen, L, Brown, A, Remy, L, Man, P, Forest, E, Barfod, L K, Adams, Y, Higgins, M K & Jensen, A T R 2015, ' Mapping the binding site of a cross-reactive Plasmodium falciparum PfEMP1 monoclonal antibody inhibitory of ICAM-1 binding ', Journal of immunology (Baltimore, Md. : 1950), vol. 195, no. 7, pp. 3273-83 .

The virulence of Plasmodium falciparum is linked to the ability of infected erythrocytes (IE) to adhere to the vascular endothelium, mediated by P. falciparum erythrocyte membrane protein 1 (PfEMP1). In this article, we report the functional characte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2751::e27d989995ef4de72b9fbc045080ec23
https://curis.ku.dk/portal/da/publications/mapping-the-binding-site-of-a-crossreactive-plasmodium-falciparum-pfemp1-monoclonal-antibody-inhibitory-of-icam1-binding(b20aa7b9-c11d-4dcc-b3e4-ad635b594db7).html