GAPR-1 Interferes with Condensate Formation of Beclin 1 in Saccharomyces cerevisiae

Autor: Sirati, Nafiseh, Shen, Ziying, Olrichs, Nick K., Popova, Blagovesta, Verhoek, Iris C., Lagerwaard, Ilse M., Braus, Gerhard H., Kaloyanova, Dora V., Helms, J.Bernd

Publikováno v: In Journal of Molecular Biology 28 February 2023 435(4)

Regulation of Functional Protein Aggregation by Multiple Factors: Implications for the Amyloidogenic Behavior of the CAP Superfamily Proteins

Autor: Sheng, Jie, Olrichs, Nick K, Gadella, Bart M, Kaloyanova, Dora V, Helms, J Bernd, LS Veterinaire biochemie, dB&C FR-RMSC FR, FAH klinische reproductie, Veterinaire biochemie, dES/dFAH FR, dB&C FR-RMSC RMSC

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 6530, p 6530 (2020)
International Journal of Molecular Sciences, 21(18). MDPI AG
International Journal of Molecular Sciences

The idea that amyloid fibrils and other types of protein aggregates are toxic for cells has been challenged by the discovery of a variety of functional aggregates. However, an identification of crucial differences between pathological and functional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b8b2ce2e1ea5d8715d11cb05d1641a
https://doi.org/10.3390/ijms21186530

Zinc binding regulates amyloid-like aggregation of GAPR-1

Autor: Sheng, Jie, Olrichs, Nick K, Geerts, Willie J, Li, Xueyi, Rehman, Ashfaq Ur, Gadella, Barend M, Kaloyanova, Dora V, Helms, J Bernd, LS Veterinaire biochemie, dB&C FR-RMSC FR, Sub Cryo - EM, dES/dFAH FR, Sub Reproductie mannelijk, Sub Biologie van de mannelijke gameet, dB&C FR-RMSC RMSC, Dep Biochemie en Celbiologie

Publikováno v: Bioscience Reports, 39(2). Portland Press Ltd.
Bioscience Reports

Members of the CAP superfamily (Cysteine-rich secretory proteins, Antigen 5, and Pathogenesis-related 1 proteins) are characterized by the presence of a CAP domain that is defined by four sequence motifs and a highly conserved tertiary structure. A c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b0a52882c515515db88de25b698b24
https://dspace.library.uu.nl/handle/1874/377965

Interaction of GAPR-1 with lipid bilayers is regulated by alternative homodimerization

Autor: van Galen, Josse, Olrichs, Nick K, Schouten, Arie, Serrano, Ramon L, Nolte-'t Hoen, Esther N M, Eerland, Ruud, Kaloyanova, Dora, Gros, Piet, Helms, J Bernd, LS Veterinaire biochemie, Sub Crystal and Structural Chemistry, Dep Biochemie en Celbiologie, LS Algemeen B&C

Publikováno v: Biochimica et Biophysica Acta, 1818(9), 2175

Golgi-Associated Plant Pathogenesis-Related protein 1 (GAPR-1) is a mammalian protein that belongs to the superfamily of plant pathogenesis related proteins group 1 (PR-1). GAPR-1 is a peripheral membrane-binding protein that strongly associates with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03dccbdd92cbf8c5fe959ccd1c5c17e3

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