Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Olof Sydow"'
Publikováno v:
Parkinson's Disease, Vol 2023 (2023)
Introduction. Parkinson’s disease (PD) is a complex multifactorial disease, involving genetic susceptibility, environmental risk factors, and gene-environmental interactions. The microbiota-gut-brain axis is hypothesized to play a role in the patho
Externí odkaz:
https://doaj.org/article/0105013703414158a400e9a034f43695
Autor:
Camilla Fardell, Anna Zettergren, Caroline Ran, Andrea Carmine Belin, Agneta Ekman, Olof Sydow, Lars Bäckman, Björn Holmberg, Nil Dizdar, Peter Söderkvist, Hans Nissbrandt
Publikováno v:
BMC Medical Genetics, Vol 19, Iss 1, Pp 1-9 (2018)
Abstract Background In this study we investigated the association between SNPs in the S100B gene and Parkinson’s disease (PD) in two independent Swedish cohorts. The SNP rs9722 has previously been shown to be associated with higher S100B concentrat
Externí odkaz:
https://doaj.org/article/203f3fde04324870a6d00a61f5455499
Autor:
Caroline Ran, Karin Wirdefeldt, Lovisa Brodin, Mehrafarin Ramezani, Marie Westerlund, Fengqing Xiang, Anna Anvret, Thomas Willows, Olof Sydow, Anders Johansson, Dagmar Galter, Per Svenningsson, Andrea Carmine Belin
Publikováno v:
Parkinson's Disease, Vol 2017 (2017)
Nuclear factor erythroid 2-like 2 (NRF2) encodes a transcription factor regulating mechanisms of cellular protection and is activated by oxidative stress. NRF2 has therefore been hypothesized to confer protection against Parkinson’s disease and so
Externí odkaz:
https://doaj.org/article/e7dbcf9dd3ef4e7a865416f7baddc886
Autor:
Anna Anvret, Caroline Ran, Marie Westerlund, Ann-Christin Thelander, Olof Sydow, Charlotta Lind, Anna Håkansson, Hans Nissbrandt, Dagmar Galter, Andrea Carmine Belin
Publikováno v:
Parkinson's Disease, Vol 2010 (2010)
Genes important for mitochondrial function have been implicated in Parkinson's disease (PD). Mitochondrial translation initiation factor 3 (MTIF3) is a nuclear encoded protein required for the initiation of complex formation on mitochondrial ribosome
Externí odkaz:
https://doaj.org/article/f79728a3ff9245f7aaf5035c75c3e2bc
Autor:
Caroline Ran, Lovisa Brodin, Sandra Gellhaar, Marie Westerlund, Camilla Fardell, Hans Nissbrandt, Peter Söderkvist, Olof Sydow, Ioanna Markaki, Ellen Hertz, Karin Wirdefeldt, Per Svenningsson
INTRODUCTION: Genetic variants in the Beta-glucocerebrosidase gene (GBA1) is a known risk factor for Parkinson's disease. The GBA1 mutations L444P, N370S and many other have been shown to associate with the disease in populations with diverse backgro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::665504aec60bfb052906cabe85ae0d2f
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-193497
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-193497
Autor:
Oskar Hansson, Håkan Widner, Jonas Kristensen, Lars Forsgren, Olof Sydow, Vincenzo Bonifati, Hans Nissbrandt, Jan Linder, Itzia Jimenez-Ferrer, Emil Ygland Rödström, Ropafadzo Mzezewa, Maria Soller, Anna Zettergren, Owen A. Ross, Karin Wirdefeldt, L.-A. Brodin, Per Svenningsson, Kajsa Brolin, Andreas Puschmann, Guido J. Breedveld, Maria Swanberg, Andrea Carmine Belin, Emma Mårtensson, Mathias Toft, Per Odin, Elin Lundblad-Andersson
Publikováno v:
Parkinsonism & Related Disorders, 66, 158-165. Elsevier
OBJECTIVE: To determine the frequency of mutations known to cause autosomal dominant Parkinson disease (PD) in a series with more than 10% of Sweden's estimated number of PD patients. METHODS: The Swedish Parkinson Disease Genetics Network was formed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb54fe3df49b0cd7ffa8ce604ee310a
https://doi.org/10.1016/j.parkreldis.2019.07.032
https://doi.org/10.1016/j.parkreldis.2019.07.032
Autor:
Olof Sydow, Karin Wirdefeldt, Fengqing Xiang, Caroline Ran, Rawand Naiel Mehdi, Hans Nissbrandt, Andrea Carmine Belin, Camilla Fardell
Publikováno v:
The Open Neurology Journal
Background:Integrin alpha 8 (ITGA8) encodes the alpha 8 subunit of the integrin alpha8beta1 protein and has recently been suggested as a new candidate gene for Parkinson’s disease, an age related neurodegenerative disease with unknown etiology. ITG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1005ee26757a5b63da6612b68435567
http://europepmc.org/articles/PMC4994103
http://europepmc.org/articles/PMC4994103
Autor:
Anna Anvret, Olof Sydow, Andrea Carmine Belin, L.-A. Brodin, Marie Westerlund, Karin Wirdefeldt, Anders Johansson, Per Svenningsson, Fengqing Xiang, Thomas Willows, Caroline Ran, Mehrafarin Ramezani, Dagmar Galter
Publikováno v:
Parkinson's Disease, Vol 2017 (2017)
Parkinson's Disease
Parkinson's Disease
Nuclear factor erythroid 2-like 2 (NRF2) encodes a transcription factor regulating mechanisms of cellular protection and is activated by oxidative stress. NRF2 has therefore been hypothesized to confer protection against Parkinson’s disease and so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1676b78d24927b770cc51de02cbeb8eb
Autor:
Anna Håkansson, Olof Sydow, Andrea Carmine Belin, Peter Söderkvist, Marie Westerlund, Thomas Willows, Anna Anvret, Hans Nissbrandt, Silvia Paddock, Caroline Ran, Ahmad Ahmadi, Dagmar Galter, Maria Anvret, Nil Dizdar
Publikováno v:
Neuroscience Letters. 522:30-35
Pesticide exposure has been suggested to increase the risk to develop Parkinson's disease (PD). The arylesterase paraoxonase 1 (PON1) is mainly expressed in the liver and hydrolyzes organophosphates such as pesticides. The polymorphism Leu54Met (rs85
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db459135a35172090fc93b52d6843e2
https://doi.org/10.1016/j.neulet.2012.06.007
https://doi.org/10.1016/j.neulet.2012.06.007
Autor:
Andrea Carmine Belin, Thomas Willows, Olof Sydow, Caroline Ran, Marie Westerlund, Lars Olson, Dagmar Galter, Anna Anvret
Publikováno v:
The Open Neurology Journal
MIRO1 and MIRO2 (mitochondrial Ras homolog gene family, member T1 and T2) also referred to as RHOT1 and RHOT2, belong to the mitochondrial Rho GTPase family and are involved in axonal transport of mitochondria in neurons. Because mitochondrial dysfun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204407a3369d701a927e969a21eaa665
https://doi.org/10.2174/1874205x01206010001
https://doi.org/10.2174/1874205x01206010001