Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Olof S. Dallner"'
Autor:
Yi-Hsueh Lu, Gulya Fayzikhodjaeva, Kıvanç Birsoy, Zhiying Li, Olof S. Dallner, Chiayun Han, Kristina Hedbacker, Chingwen Yang, Jeffrey M. Friedman
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Adipogenesis in adulthood replaces fat cells that turn over and can contribute to the development of obesity. However, the proliferative potential of adipocyte progenitors in vivo is unknown (Faust et al., 1976; Faust et al., 1977; Hirsch and Han, 19
Autor:
Jeffrey M. Friedman, Kristina Hedbacker, Yi-Hsueh Lu, Olof S. Dallner, Chiayun Han, Chingwen Yang, Kıvanç Birsoy, Zhiying Li, Gulya Fayzikhodjaeva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a3124fec5ec22f8e0dfd3d1351ce512
https://doi.org/10.7554/elife.53074.sa2
https://doi.org/10.7554/elife.53074.sa2
Autor:
Brian D. Dill, Lu Yh, Olof S. Dallner, Arden Moscati, Kıvanç Birsoy, Jill M. Marinis, Zoltán Kutalik, Allan Linneberg, Niels Grarup, Henrik Molina, Jeffrey M. Friedman, Loos Rjf., Mitchell A. Lazar, Pedro Marques-Vidal, Tuomas O. Kilpeläinen, Roger D. Vaughan, Yinxin Zhang, Werner E, Gulya Fayzikhodjaeva
Publikováno v:
Yearbook of Paediatric Endocrinology.
Autor:
Gulya Fayzikhodjaeva, Tomoyoshi Nakadai, Yi-Hsueh Lu, Mitchell A. Lazar, Yinxin Zhang, Jeffrey M. Friedman, Olof S. Dallner, Robert G. Roeder
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Leptin gene expression is highly correlated with the lipid content of individual fat cells, suggesting that it is regulated by a “fat-sensing” signal transduction pathway. This possibility is thus analogous to the identification of a
Autor:
Emory Werner, Zoltán Kutalik, Yi-Hsueh Lu, Jeffrey M. Friedman, Jill M. Marinis, Henrik Molina, Arden Moscati, Brian D. Dill, Gulya Fayzikhodjaeva, Kıvanç Birsoy, Yinxin Zhang, Ruth J. F. Loos, Niels Grarup, Olof S. Dallner, Mitchell A. Lazar, Tuomas O. Kilpeläinen, Roger D. Vaughan, Pedro Marques-Vidal, Allan Linneberg
Publikováno v:
Cell Metab
Quantitative changes in leptin concentration lead to alterations in food intake and body weight, but the regulatory mechanisms that control leptin gene expression are poorly understood. Here we report that fat-specific and quantitative leptin express
Publikováno v:
Molecular Metabolism, Vol 4, Iss 5, Pp 392-405 (2015)
Molecular Metabolism
Molecular Metabolism
Objective Leptin gene expression is highly correlated with cellular lipid content in adipocytes but the transcriptional mechanisms controlling leptin expression in vivo are poorly understood. In this report, we set out to identify cis - and trans -re
Autor:
Julia Nevzorova, Tore Bengtsson, Jon Merlin, Olof S. Dallner, Roger J. Summers, Nodi Dehvari, Dana S. Hutchinson, Masaaki Sato, Bronwyn A Evans, Martina Kocan
Publikováno v:
British Journal of Pharmacology. 165:1442-1456
BACKGROUND AND PURPOSE β-Adrenoceptor stimulation induces glucose uptake in several insulin-sensitive tissues by poorly understood mechanisms. EXPERIMENTAL APPROACH We used a model system in CHO-K1 cells expressing the human β2-adrenoceptor and glu
Autor:
Lillian B. Cohn, Cristina Mascaraque, Pedro M. Moraes-Vieira, Bernardo S. Reis, Manal Amoury, Ana Domingos, Olof S. Dallner, Melania H. Fanok, Daniel Mucida, Aneta Rogoz, Kihyun Lee
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 194(11)
The hormone leptin plays a key role in energy homeostasis, and the absence of either leptin or its receptor (LepR) leads to severe obesity and metabolic disorders. To avoid indirect effects and to address the cell-intrinsic role of leptin signaling i
Autor:
Tore Bengtsson, Didier F. Pisani, Dana S. Hutchinson, Jean-Claude Chambard, Anna L. Sandström, Ez-Zoubir Amri, Jessica M. Olsen, Masaaki Sato, Olof S. Dallner
Publikováno v:
The Journal of Cell Biology
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2014, 207 (3), pp.365-74
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2014, 207 (3), pp.365-74
β3-Adrenoceptors promote glucose uptake in brown adipose tissue via both cAMP-mediated increases in GLUT1 transcription and mTORC2-stimulated translocation of newly synthesized GLUT1 to the plasma membrane.
Brown adipose tissue is the primary s
Brown adipose tissue is the primary s
Publikováno v:
Diabetologia. 48:2386-2395
Brown adipocytes provide a potentially important model system for understanding AMP-activated protein kinase (AMPK) regulation, where adrenergic stimulation leads to mitochondrial uncoupling through uncoupling protein-1 (UCP1) activity. AMPK is a sen