Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Olof Idevall-Hagren"'
Autor:
Paul O’Callaghan, Olof Idevall-Hagren
Publikováno v:
ACS Central Science, Vol 10, Iss 3, Pp 514-516 (2024)
Externí odkaz:
https://doaj.org/article/2cfb1ec508b74f18847cea12bd42a199
Autor:
Styliani Panagiotou, Kia Wee Tan, Phuoc My Nguyen, Andreas Müller, Affiong Ika Oqua, Alejandra Tomas, Anna Wendt, Lena Eliasson, Anders Tengholm, Michele Solimena, Olof Idevall-Hagren
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 113992- (2024)
Summary: Insulin is packaged into secretory granules that depart the Golgi and undergo a maturation process that involves changes in the protein and lipid composition of the granules. Here, we show that insulin secretory granules form physical contac
Externí odkaz:
https://doaj.org/article/ab020b44d66c4d84917ebea44d0e0a85
Autor:
Anongnad Ngamjariyawat, Jing Cen, Romain Said, Ceren Incedal, Olof Idevall-Hagren, Nils Welsh
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionHigh intracellular concentrations of adenosine and 2’-deoxyadenosine have been suggested to be an important mediator of cell death. The aim of the present study was to characterize adenosine-induced death in insulin-producing beta-cells
Externí odkaz:
https://doaj.org/article/f1f7c676e6c84e5fa5502bc95c19b53f
Autor:
Styliani Panagiotou, Phuoc My Nguyen, Kia Wee Tan, Andreas Müller, Anna Wendt, Lena Eliasson, Anders Tengholm, Michele Solimena, Olof Idevall-Hagren
Insulin secretion is the process whereby insulin-containing granules fuse with the plasma membrane of β-cells. Exocytosis is preceded by cargo loading, maturation and transport of the secretory granules; processes that require modification of both t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e80ed8e01526a5cd986704e976a63f11
https://doi.org/10.1101/2023.02.22.529485
https://doi.org/10.1101/2023.02.22.529485
Autor:
Alex Montoya, Emirhan Tasoez, Holger Kramer, Olof Idevall-Hagren, S Neda Mousavy Gharavy, Steven Millership, Mark Ibberson, Ming Hu, Aida Martinez-Sanchez, Paul Gadue, Eleni Georgiadou, Isabelle Leclerc, Dominic J. Withers, Nikolay Ninov, Bryn M. Owen, Pauline Chabosseau, Grazia Pizza, David A. Jacobson, Matthew T. Dickerson, Fabian L. Cardenas-Diaz, Zenobia B. Mehta, Marianne Voz, Christophe Magnan, Céline Cruciani-Guglielmacci, Nicholas H. F. Fine, Guy A. Rutter
Publikováno v:
Diabetologia
Diabetologia, 2021, 64 (4), pp.850-864. ⟨10.1007/s00125-020-05350-x⟩
Diabetologia, 2021, 64 (4), pp.850-864. ⟨10.1007/s00125-020-05350-x⟩
Aims/hypothesis Variants close to the VPS13C/C2CD4A/C2CD4B locus are associated with altered risk of type 2 diabetes in genome-wide association studies. While previous functional work has suggested roles for VPS13C and C2CD4A in disease development,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3515d1e5f62db8cf8036e2aa24a6876b
http://europepmc.org/articles/PMC7829492
http://europepmc.org/articles/PMC7829492
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2483
A wide range of fluorescent sensors with different properties have been developed for imaging of cAMP signals in living cells and tissues. Most cAMP reporters have been designed to undergo changes in fluorescence resonance energy transfer but there a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::695289bb57d378f245638a161595541a
https://pubmed.ncbi.nlm.nih.gov/35286685
https://pubmed.ncbi.nlm.nih.gov/35286685
Autor:
Olof Idevall-Hagren, Xiaogang Guo, Lei Wang, Xuqin Zhao, Ping Shentu, Jiannan Fan, Hanbing Li, Hong Li, Mei Xiao, Yinyan Lin, Yingke Xu, Xuechun Liu
Publikováno v:
Journal of Molecular Biology. 432:4341-4357
Phosphoinositides are important signaling molecules involved in the regulation of vesicular trafficking. It has been implicated that phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2] is involved in insulin-regulated GLUT4 translocation in adipocytes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ff9cf7f14fe96f4e5fa57b4a89d20ee
https://doi.org/10.1016/j.jmb.2020.06.019
https://doi.org/10.1016/j.jmb.2020.06.019
Publikováno v:
cAMP Signaling ISBN: 9781071622445
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebf03b5a31c2f29c2476f9c6f8779b08
https://doi.org/10.1007/978-1-0716-2245-2_20
https://doi.org/10.1007/978-1-0716-2245-2_20
Autor:
Gonzalo Manuel, Sanchez, Tugce Ceren, Incedal, Juan, Prada, Paul, O'Callaghan, Oleg, Dyachok, Santiago, Echeverry, Özge, Dumral, Phuoc My, Nguyen, Beichen, Xie, Sebastian, Barg, Johan, Kreuger, Thomas, Dandekar, Olof, Idevall-Hagren
Publikováno v:
The Journal of cell biology. 222(1)
The primary cilium is an organelle present in most adult mammalian cells that is considered as an antenna for sensing the local microenvironment. Here, we use intact mouse pancreatic islets of Langerhans to investigate signaling properties of the pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dd1eb616799fabea47a19fd4021e5af9
https://pubmed.ncbi.nlm.nih.gov/36350286
https://pubmed.ncbi.nlm.nih.gov/36350286
Autor:
Beichen Xie, Phuoc My Nguyen, Paul O'Callaghan, T. C. Incedal, Olof Idevall-Hagren, S. Echeverry, Johan Kreuger, Juan P. Prada Salcedo, Thomas Dandekar, Sebastian Barg, Gonzalo Sanchez
The primary cilium is an organelle present in most adult mammalian cells and is thought of as an antenna for detection of a variety of signals. Here we use intact mouse pancreatic islets of Langerhans to investigate signalling properties of the prima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::500f7c6c09cf897265b7eadb695b9451
https://doi.org/10.1101/2021.08.16.456473
https://doi.org/10.1101/2021.08.16.456473