Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Olof Gidlöf"'
Autor:
Nilanjana Ghosh, Carl Lejonberg, Tomasz Czuba, Koen Dekkers, Richard Robinson, Johan Ärnlöv, Olle Melander, Maya Landenhed Smith, Anne M. Evans, Olof Gidlöf, Robert E. Gerszten, Lars Lind, Gunnar Engström, Tove Fall, J. Gustav Smith
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Plasma metabolomics holds potential for precision medicine, but limited information is available to compare the performance of such methods across multiple cohorts. We compared plasma metabolite profiles after an overnight fast in 11,309 par
Externí odkaz:
https://doaj.org/article/07c3b0b4011d4fd3972f0e6ac665caac
Autor:
Anna Egerstedt, John Berntsson, Maya Landenhed Smith, Olof Gidlöf, Roland Nilsson, Mark Benson, Quinn S. Wells, Selvi Celik, Carl Lejonberg, Laurie Farrell, Sumita Sinha, Dongxiao Shen, Jakob Lundgren, Göran Rådegran, Debby Ngo, Gunnar Engström, Qiong Yang, Thomas J. Wang, Robert E. Gerszten, J. Gustav Smith
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Heart failure is a major health issue worldwide. Here, Egerstedt et al. perform proteomic profiling of human plasma at different stages of heart failure, providing a comprehensive analysis of changes in the plasma proteome during disease progression.
Externí odkaz:
https://doaj.org/article/8631686d85f7447fbe8d13055384ccaf
Autor:
Olof Gidlöf
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
The natriuretic peptide system (NPS) plays a fundamental role in maintaining cardiorenal homeostasis, and its potent filling pressure-regulated diuretic and vasodilatory effects constitute a beneficial compensatory mechanism in heart failure (HF). Le
Externí odkaz:
https://doaj.org/article/60a8d0908c1d4b64b04c8fb9888d6a43
Autor:
Neha Pimpalwar, Tomasz Czuba, Maya Landenhed Smith, Johan Nilsson, Olof Gidlöf, J. Gustav Smith
Publikováno v:
Heliyon, Vol 6, Iss 12, Pp e05810- (2020)
Background: Global transcriptional profiling of individual cells represents a powerful approach to systematically survey contributions from cell-specific molecular phenotypes to human disease states but requires tissue-specific protocols. Here we sou
Externí odkaz:
https://doaj.org/article/b11fba1d0dd14b32be4009447f2e06d3
Autor:
Ihdina Sukma Dewi, Zsuzsanna Hollander, Karen K Lam, Janet-Wilson McManus, Scott J Tebbutt, Raymond T Ng, Paul A Keown, Robert W McMaster, Bruce M McManus, Olof Gidlöf, Jenny Öhman
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170842 (2017)
Identifying non-invasive and reliable blood-derived biomarkers for early detection of acute cellular rejection in heart transplant recipients is of great importance in clinical practice. MicroRNAs are small molecules found to be stable in serum and t
Externí odkaz:
https://doaj.org/article/58e3247693cc40abb5f0f41b72af42b0
Autor:
Olof Gidlöf, Andrea L. Johnstone, Kerstin Bader, Bohdan B. Khomtchouk, Jiaqi J. O'Reilly, Selvi Celik, Derek J. Van Booven, Claes Wahlestedt, Bernhard Metzler, David Erlinge
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 12 (2016)
BackgroundIschemic preconditioning (IPC) protects the heart from prolonged ischemic insult and reperfusion injury through a poorly understood mechanism. Post‐translational modifications of histone residues can confer rapid and drastic switches in g
Externí odkaz:
https://doaj.org/article/ac44d4ee7c3e48728a41c0b1940b60c4
Autor:
J Gustav Smith, Janine F Felix, Alanna C Morrison, Andreas Kalogeropoulos, Stella Trompet, Jemma B Wilk, Olof Gidlöf, Xinchen Wang, Michael Morley, Michael Mendelson, Roby Joehanes, Symen Ligthart, Xiaoyin Shan, Joshua C Bis, Ying A Wang, Marketa Sjögren, Julius Ngwa, Jeffrey Brandimarto, David J Stott, David Aguilar, Kenneth M Rice, Howard D Sesso, Serkalem Demissie, Brendan M Buckley, Kent D Taylor, Ian Ford, Chen Yao, Chunyu Liu, CHARGE-SCD consortium, EchoGen consortium, QT-IGC consortium, CHARGE-QRS consortium, Nona Sotoodehnia, Pim van der Harst, Bruno H Ch Stricker, Stephen B Kritchevsky, Yongmei Liu, J Michael Gaziano, Albert Hofman, Christine S Moravec, André G Uitterlinden, Manolis Kellis, Joyce B van Meurs, Kenneth B Margulies, Abbas Dehghan, Daniel Levy, Björn Olde, Bruce M Psaty, L Adrienne Cupples, J Wouter Jukema, Luc Djousse, Oscar H Franco, Eric Boerwinkle, Laurie A Boyer, Christopher Newton-Cheh, Javed Butler, Ramachandran S Vasan, Thomas P Cappola, Nicholas L Smith
Publikováno v:
PLoS Genetics, Vol 12, Iss 5, p e1006034 (2016)
Failure of the human heart to maintain sufficient output of blood for the demands of the body, heart failure, is a common condition with high mortality even with modern therapeutic alternatives. To identify molecular determinants of mortality in pati
Externí odkaz:
https://doaj.org/article/a9d75c26c69d4565b9910119307e9517
Publikováno v:
BioTechniques, Vol 47, Iss 2, Pp 671-678 (2009)
Analysis of mitochondrial DNA in forensic samples is routinely carried out by direct sequencing of hypervariable regions within the non-coding displacement loop. Although the accuracy and sensitivity of this method cannot be questioned, it is both ti
Externí odkaz:
https://doaj.org/article/16d821d5f7f141bc9d590924381cdbf0
Autor:
Olof Gidlöf, J Gustav Smith, Olle Melander, Håkan Lövkvist, Bo Hedblad, Gunnar Engström, Peter Nilsson, Joyce Carlson, Göran Berglund, Sandra Olsson, Katarina Jood, Christina Jern, Bo Norrving, Arne Lindgren, David Erlinge
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37491 (2012)
BACKGROUND AND PURPOSE: Extracellular adenosine triphosphate (ATP) regulates inflammatory cells by activation of the P2X(7) receptor. We hypothesized that polymorphisms in P2RX7 influence the risk of ischemic heart disease (IHD), ischemic stroke (IS)
Externí odkaz:
https://doaj.org/article/7c7d97321bad48b787d316ef98ebac3d
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17672 (2011)
Diamond-Blackfan anemia (DBA) is a lineage specific and congenital erythroblastopenia. The disease is associated with mutations in genes encoding ribosomal proteins resulting in perturbed ribosomal subunit biosynthesis. The RPS19 gene is mutated in a
Externí odkaz:
https://doaj.org/article/0aea4025dfc44fe1bedf6944b362347e