Efficacy and safety of olmesartan medoxomil-amlodipine besylate tablet in Chinese patients with essential hypertension: A prospective, single-arm, multi-center, real-world study.

Autor: Cui Z; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China., Qiu Z; Department of Cardiology, Shanghai Tongren Hospital, Shanghai, China., Cheng W; Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China., Hu W; Department of Cardiology, Central Hospital of Minhang District, Shanghai, China., Ma G; Department of Cardiology, Zhongda Hospital Affiliated to Southeast University, Nanjing, China., Cai X; Department of Cardiology, Jinan Central Hospital, Jinan, China., Jin Y; Department of Cardiology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Zhao Y; Department of Cardiology, Dalian Jinzhou First People's Hospital, Dalian, China., He L; Department of Cardiology, Wuhan No. 1 Hospital, Wuhan, China., Li Y; Department of Cardiology, Shanghai East Hospital, Shanghai, China., Bu P; Department of Cardiology, Qilu Hospital of Shandong University, Jinan, China., Chen X; Department of Cardiology, West China Hospital of Sichuan University, Chengdu, China., Wang R; Department of Cardiology, Wuxi People's Hospital, Wuxi, China., Chen L; Department of Cardiology, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China., Dong P; Department of Cardiology, Beijing Aviation General Hospital, Beijing, China., Feng L; Department of Cardiology, Shidong Hospital, Yangpu District, Shanghai, China., Han X; Department of Cardiology, Shanxi Cardiovascular Hospital (Shanxi Cardiovascular Diseases Institute), Taiyuan, China., Hong M; Department of Cardiology, The Second Clinical Medical College of Nanjing Medical University, Nanjing, China., Hou Y; Department of Cardiology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, China., Liao M; Department of Cardiology, Baoshan Branch, Shanghai General Hospital, Shanghai, China., Wang M; Department of Cardiology, Putuo People's Hospital, Tongji University, Shanghai, China., Wang X; Department of Cardiology, Wuxi Third People's Hospital, Wuxi, China., Xie J; Department of Cardiology, Zhejiang Provincial People's Hospital, Hangzhou, China., Xu Y; Department of Cardiology, Shanghai Tenth People's Hospital, Shanghai, China., Wang Z; Department of Cardiology, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China., Huang K; Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Li Y; Department of Cardiology, Tianjin Medical University General Hospital, Tianjin, China., Li D; Department of Cardiology, Wuhan Third Hospital, Wuhan, China., Ji X; Department of Cardiology, Wenzhou Central Hospital, Wenzhou, China., Huang J; Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China., Wang J; Department of Cardiology, Jing'an District Central Hospital of Shanghai, Shanghai, China., Fang D; Department of Cardiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China., Wang J; Department of Cardiology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China., Tang L; Department of Cardiology, Zhejiang Hospital, Hangzhou, China., Liu Y; Department of Cardiology, Tianjin Third Central Hospital, Tianjin, China., Fu G; Department of Cardiology, Sir Run Run Shaw Hospital of Zhejiang University School of Medicine, Hangzhou, China., Du J; Medical Department, Daiichi Sankyo (China) Holdings Co., Ltd, Shanghai, China., Wang L; Medical Department, Daiichi Sankyo (China) Holdings Co., Ltd, Shanghai, China., Liu M; Medical Department, Daiichi Sankyo (China) Holdings Co., Ltd, Shanghai, China., Ge J; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.

Publikováno v: Journal of clinical hypertension (Greenwich, Conn.) [J Clin Hypertens (Greenwich)] 2024 Jan; Vol. 26 (1), pp. 5-16. Date of Electronic Publication: 2023 Sep 04.

Conversion of Olmesartan to Olmesartan Medoxomil, A Prodrug that Improves Intestinal Absorption, Confers Substrate Recognition by OATP2B1.

Autor: Fukazawa N; Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku 105-8512, Tokyo, Japan., Nishimura T; Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku 105-8512, Tokyo, Japan., Orii K; Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku 105-8512, Tokyo, Japan., Noguchi S; Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku 105-8512, Tokyo, Japan., Tomi M; Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku 105-8512, Tokyo, Japan. tomi-ms@pha.keio.ac.jp.

Publikováno v: Pharmaceutical research [Pharm Res] 2024 May; Vol. 41 (5), pp. 849-861. Date of Electronic Publication: 2024 Mar 14.

The enhancement effect of small molecule Lyb24 reveals AzoR as a novel target of polymyxin B.

Autor: Hu C; Department of Medical Laboratory, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China; Antimicrobial Drug Screening Laboratory, Shenzhen Institute of Respiratory Diseases, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China., Zhang J; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Shapingba District, 400038 Chongqing, China., Cui R; Department of Medical Laboratory, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China; Antimicrobial Drug Screening Laboratory, Shenzhen Institute of Respiratory Diseases, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China., Liu S; Department of Medical Laboratory, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China; Antimicrobial Drug Screening Laboratory, Shenzhen Institute of Respiratory Diseases, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China., Huang Y; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, Guangdong, China., Zeng H; Antimicrobial Drug Screening Laboratory, Shenzhen Institute of Respiratory Diseases, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China; College of Pharmacy, Jinan University, Guangzhou 510632, Guangdong, China., Cheng S; Department of Medical Laboratory, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China; Antimicrobial Drug Screening Laboratory, Shenzhen Institute of Respiratory Diseases, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China., Zhou G; Department of Pharmacy, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China., Li J; Beijing Qinglian Biotech Co.,Ltd, Haidian District, 100094 Beijing, China., Sun L; Beijing Qinglian Biotech Co.,Ltd, Haidian District, 100094 Beijing, China., Zhao Y; Beijing Qinglian Biotech Co.,Ltd, Haidian District, 100094 Beijing, China., Wang X; Department of Pharmacy, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China., Liu J; College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, Guangdong, China., Zou Q; National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, College of Pharmacy, Third Military Medical University, Shapingba District, 400038 Chongqing, China. Electronic address: qmzou2007@163.com., Huang W; Department of Medical Laboratory, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China; Antimicrobial Drug Screening Laboratory, Shenzhen Institute of Respiratory Diseases, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China; Division of Hepatobiliary and Pancreas surgery, Department of General Surgery, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen 518020, Guangdong, China. Electronic address: whuang_sz@163.com.

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Dec 31; Vol. 169, pp. 115856. Date of Electronic Publication: 2023 Nov 10.

Diverse but desolate landscape of gut microbial azoreductases: A rationale for idiopathic IBD drug response.

Autor: Simpson JB; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Sekela JJ; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Carry BS; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Beaty V; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Patel S; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Redinbo MR; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Biochemistry and Biophysics, Department of Microbiology and Immunology, and the Integrated Program for Biological and Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Publikováno v: Gut microbes [Gut Microbes] 2023 Jan-Dec; Vol. 15 (1), pp. 2203963.

Acute quadruple extremity compartment syndrome due to angio-oedema after polypharmacy overdose including olmesartan medoxomil, telmisartan and vildagliptin.

Autor: Kono Y; Department of Intensive Care Medicine, Kameda Medical Center, Kamogawa, Japan., Takimoto K; Department of Intensive Care Medicine, Kameda Medical Center, Kamogawa, Japan mm7706tk@gmail.com., Fujii M; Department of Intensive Care Medicine, Kameda Medical Center, Kamogawa, Japan., Hayashi Y; Department of Intensive Care Medicine, Kameda Medical Center, Kamogawa, Japan.

Publikováno v: BMJ case reports [BMJ Case Rep] 2024 Apr 02; Vol. 17 (4). Date of Electronic Publication: 2024 Apr 02.