Systematic analysis of the Candida albicans kinome reveals environmentally contingent protein kinase-mediated regulation of filamentation and biofilm formation in vitro and in vivo .

Autor: Kramara J; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Kim M-J; Department of Microbiology, University of Georgia, Athens, Georgia, USA., Ollinger TL; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Ristow LC; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Wakade RS; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Zarnowski R; Department of Medicine, Section of Infectious Disease, University of Wisconsin, Madison, Wisconsin, USA.; Department of Medical Microbiology and Immunology, University of Wisconsin, Madison, Wisconsin, USA., Wellington M; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Andes DR; Department of Medicine, Section of Infectious Disease, University of Wisconsin, Madison, Wisconsin, USA.; Department of Medical Microbiology and Immunology, University of Wisconsin, Madison, Wisconsin, USA., Mitchell AG; Department of Microbiology, University of Georgia, Athens, Georgia, USA., Krysan DJ; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.; Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.

Publikováno v: MBio [mBio] 2024 Aug 14; Vol. 15 (8), pp. e0124924. Date of Electronic Publication: 2024 Jul 01.

Loss-of-Function ROX1 Mutations Suppress the Fluconazole Susceptibility of upc2A Δ Mutation in Candida glabrata, Implicating Additional Positive Regulators of Ergosterol Biosynthesis.

Autor: Ollinger TL; Department of Pediatrics, Carver College of Medicine, University of Iowagrid.412584.egrid.214572.7, Iowa City, Iowa, USA., Vu B; Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowagrid.412584.egrid.214572.7, Iowa City, Iowa, USA., Murante D; Department of Pediatrics, Carver College of Medicine, University of Iowagrid.412584.egrid.214572.7, Iowa City, Iowa, USA., Parker JE; Institute of Life Sciences, Swansea Universitygrid.4827.9 Medical School, Swansea University, Swansea, Wales, United Kingdom., Simonicova L; Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowagrid.412584.egrid.214572.7, Iowa City, Iowa, USA., Doorley L; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Stamnes MA; Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowagrid.412584.egrid.214572.7, Iowa City, Iowa, USA., Kelly SL; Institute of Life Sciences, Swansea Universitygrid.4827.9 Medical School, Swansea University, Swansea, Wales, United Kingdom., Rogers PD; Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA., Moye-Rowley WS; Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowagrid.412584.egrid.214572.7, Iowa City, Iowa, USA., Krysan DJ; Department of Pediatrics, Carver College of Medicine, University of Iowagrid.412584.egrid.214572.7, Iowa City, Iowa, USA.; Department of Microbiology and Immunology, Carver College of Medicine, University of Iowagrid.412584.egrid.214572.7, Iowa City, Iowa, USA.

Publikováno v: MSphere [mSphere] 2021 Dec 22; Vol. 6 (6), pp. e0083021. Date of Electronic Publication: 2021 Dec 22.

Candida glabrata maintains two HAP1 ohnologs, HAP1A and HAP1B, for distinct roles in ergosterol gene regulation to mediate sterol homeostasis under azole and hypoxic conditions.

Autor: Saha, Debasmita, Gregor, Justin B., Hoda, Smriti, Eastman, Katharine E., Gutierrez-Schultz, Victor A., Navarrete, Mindy, Wisecaver, Jennifer H., Briggs, Scott D.

Publikováno v: MSphere; Nov2024, Vol. 9 Issue 11, p1-27, 27p

Candida albicans commensalism in the oral mucosa is favoured by limited virulence and metabolic adaptation.

Autor: Lemberg, Christina^1,2 (AUTHOR), Martinez de San Vicente, Kontxi^1,2 (AUTHOR), Fróis-Martins, Ricardo^1,2 (AUTHOR), Altmeier, Simon^1,2 (AUTHOR), Tran, Van Du T.³ (AUTHOR), Mertens, Sarah^1,2 (AUTHOR), Amorim-Vaz, Sara⁴ (AUTHOR), Rai, Laxmi Shanker⁵ (AUTHOR), d'Enfert, Christophe⁵ (AUTHOR), Pagni, Marco³ (AUTHOR), Sanglard, Dominique⁴ (AUTHOR), LeibundGut-Landmann, Salomé^1,2 (AUTHOR) salome.leibundgut-landmann@uzh.ch

Publikováno v: PLoS Pathogens. 4/11/2022, Vol. 18 Issue 4, p1-33. 33p.