Zobrazeno 1 - 10
of 290
pro vyhledávání: '"Ollier, William E R"'
Autor:
Okbay, Aysu, Wu, Yeda, Wang, Nancy, Jayashankar, Hariharan, Bennett, Michael, Nehzati, Seyed Moeen, Sidorenko, Julia, Kweon, Hyeokmoon, Goldman, Grant, Gjorgjieva, Tamara, Jiang, Yunxuan, Hicks, Barry, Tian, Chao, Hinds, David A., Ahlskog, Rafael, Magnusson, Patrik K. E., Oskarsson, Sven, Hayward, Caroline, Campbell, Archie, Porteous, David J., Freese, Jeremy, Herd, Pamela, Agee, Michelle, Alipanahi, Babak, Auton, Adam, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Fontanillas, Pierre, Furlotte, Nicholas A., Huber, Karen E., Kleinman, Aaron, Litterman, Nadia K., McCreight, Jennifer C., McIntyre, Matthew H., Mountain, Joanna L., Northover, Carrie A. M., Pitts, Steven J., Sathirapongsasuti, J. Fah, Sazonova, Olga V., Shelton, Janie F., Shringarpure, Suyash, Tung, Joyce Y., Vacic, Vladimir, Wilson, Catherine H., Fontana, Mark Alan, Pers, Tune H., Rietveld, Cornelius A., Chen, Guo-Bo, Emilsson, Valur, Meddens, S. Fleur W., Pickrell, Joseph K., Thom, Kevin, Timshel, Pascal, de Vlaming, Ronald, Abdellaoui, Abdel, Ahluwalia, Tarunveer S., Bacelis, Jonas, Baumbach, Clemens, Bjornsdottir, Gyda, Brandsma, Johannes H., Concas, Maria Pina, Derringer, Jaime, Galesloot, Tessel E., Girotto, Giorgia, Gupta, Richa, Hall, Leanne M., Harris, Sarah E., Hofer, Edith, Horikoshi, Momoko, Huffman, Jennifer E., Kaasik, Kadri, Kalafati, Ioanna P., Karlsson, Robert, Lahti, Jari, van der Lee, Sven J., de Leeuw, Christiaan, Lind, Penelope A., Lindgren, Karl-Oskar, Liu, Tian, Mangino, Massimo, Marten, Jonathan, Mihailov, Evelin, Miller, Michael B., van der Most, Peter J., Oldmeadow, Christopher, Payton, Antony, Pervjakova, Natalia, Peyrot, Wouter J., Qian, Yong, Raitakari, Olli, Rueedi, Rico, Salvi, Erika, Schmidt, Börge, Schraut, Katharina E., Shi, Jianxin, Smith, Albert V., Poot, Raymond A., Pourcain, Beate St, Teumer, Alexander, Thorleifsson, Gudmar, Verweij, Niek, Vuckovic, Dragana, Wellmann, Juergen, Westra, Harm-Jan, Yang, Jingyun, Zhao, Wei, Zhu, Zhihong, Alizadeh, Behrooz Z., Amin, Najaf, Bakshi, Andrew, Baumeister, Sebastian E., Biino, Ginevra, Bønnelykke, Klaus, Boyle, Patricia A., Campbell, Harry, Cappuccio, Francesco P., Davies, Gail, De Neve, Jan-Emmanuel, Deloukas, Panos, Demuth, Ilja, Ding, Jun, Eibich, Peter, Eisele, Lewin, Eklund, Niina, Evans, David M., Faul, Jessica D., Feitosa, Mary F., Forstner, Andreas J., Gandin, Ilaria, Gunnarsson, Bjarni, Halldórsson, Bjarni V., Harris, Tamara B., Heath, Andrew C., Hocking, Lynne J., Holliday, Elizabeth G., Homuth, Georg, Horan, Michael A., Hottenga, Jouke-Jan, de Jager, Philip L., Joshi, Peter K., Jugessur, Astanand, Kaakinen, Marika A., Kähönen, Mika, Kanoni, Stavroula, Keltigangas-Järvinen, Liisa, Kiemeney, Lambertus A. L. M., Kolcic, Ivana, Koskinen, Seppo, Kraja, Aldi T., Kroh, Martin, Kutalik, Zoltan, Latvala, Antti, Launer, Lenore J., Lebreton, Maël P., Levinson, Douglas F., Lichtenstein, Paul, Lichtner, Peter, Liewald, David C. M., Loukola, Anu, Madden, Pamela A., Mägi, Reedik, Mäki-Opas, Tomi, Marioni, Riccardo E., Marques-Vidal, Pedro, Meddens, Gerardus A., McMahon, George, Meisinger, Christa, Meitinger, Thomas, Milaneschi, Yusplitri, Milani, Lili, Montgomery, Grant W., Myhre, Ronny, Nelson, Christopher P., Nyholt, Dale R., Ollier, William E. R., Palotie, Aarno, Paternoster, Lavinia, Pedersen, Nancy L., Petrovic, Katja E., Räikkönen, Katri, Ring, Susan M., Robino, Antonietta, Rostapshova, Olga, Rudan, Igor, Rustichini, Aldo, Salomaa, Veikko, Sanders, Alan R., Sarin, Antti-Pekka, Schmidt, Helena, Scott, Rodney J., Smith, Blair H., Smith, Jennifer A., Staessen, Jan A., Steinhagen-Thiessen, Elisabeth, Strauch, Konstantin, Terracciano, Antonio, Tobin, Martin D., Ulivi, Sheila, Vaccargiu, Simona, Quaye, Lydia, van Rooij, Frank J. A., Venturini, Cristina, Vinkhuyzen, Anna A. E., Völker, Uwe, Völzke, Henry, Vonk, Judith M., Vozzi, Diego, Waage, Johannes, Ware, Erin B., Willemsen, Gonneke, Attia, John R., Bennett, David A., Berger, Klaus, Bertram, Lars, Bisgaard, Hans, Boomsma, Dorret I., Borecki, Ingrid B., Bültmann, Ute, Chabris, Christopher F., Cucca, Francesco, Cusi, Daniele, Deary, Ian J., Dedoussis, George V., van Duijn, Cornelia M., Eriksson, Johan G., Franke, Barbara, Franke, Lude, Gasparini, Paolo, Gejman, Pablo V., Gieger, Christian, Grabe, Hans-Jörgen, Gratten, Jacob, Groenen, Patrick J. F., Gudnason, Vilmundur, van der Harst, Pim, Hoffmann, Wolfgang, Hyppönen, Elina, Iacono, William G., Jacobsson, Bo, Järvelin, Marjo-Riitta, Jöckel, Karl-Heinz, Kaprio, Jaakko, Kardia, Sharon L. R., Lehtimäki, Terho, Lehrer, Steven F., Martin, Nicholas G., McGue, Matt, Metspalu, Andres, Pendleton, Neil, Penninx, Brenda W. J. H., Perola, Markus, Pirastu, Nicola, Pirastu, Mario, Polasek, Ozren, Posthuma, Danielle, Power, Christine, Province, Michael A., Samani, Nilesh J., Schlessinger, David, Schmidt, Reinhold, Sørensen, Thorkild I. A., Spector, Tim D., Stefansson, Kari, Thorsteinsdottir, Unnur, Thurik, A. Roy, Timpson, Nicholas J., Tiemeier, Henning, Uitterlinden, André G., Vitart, Veronique, Vollenweider, Peter, Weir, David R., Wilson, James F., Wright, Alan F., Conley, Dalton C., Krueger, Robert F., Smith, George Davey, Hofman, Albert, Laibson, David I., Medland, Sarah E., Yang, Jian, Esko, Tõnu, Watson, Chelsea, Jala, Jonathan, Conley, Dalton, Koellinger, Philipp D., Johannesson, Magnus, Laibson, David, Meyer, Michelle N., Lee, James J., Kong, Augustine, Yengo, Loic, Cesarini, David, Turley, Patrick, Visscher, Peter M., Beauchamp, Jonathan P., Benjamin, Daniel J., Young, Alexander I.
Publikováno v:
2022, ' Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals ', Nature Genetics, vol. 54, no. 4, pp. 437-449 . https://doi.org/10.1038/s41588-022-01016-z
Okbay, A, Wu, Y, Wang, N, Jayashankar, H, Bennett, M, Nehzati, S M, Sidorenko, J, Kweon, H, Goldman, G, Gjorgjieva, T, Jiang, Y, Hicks, B, Tian, C, Hinds, D A, Ahlskog, R, Magnusson, P K E, Oskarsson, S, Hayward, C, Campbell, A, Porteous, D J, Freese, J, Herd, P, Agee, M, Alipanahi, B, Auton, A, Bell, R K, Bryc, K, Elson, S L, Fontanillas, P, Furlotte, N A, Hinds, D A, Huber, K E, Kleinman, A, Litterman, N K, McCreight, J C, McIntyre, M H, Mountain, J L, Northover, C A M, Pitts, S J, Sathirapongsasuti, J F, Sazonova, O V, Shelton, J F, Pers, T H, Timshel, P, Ahluwalia, T S, Bønnelykke, K, Bisgaard, H, Sørensen, T I A, 23andMe Research Team, Social Science Genetic Association Consortium & LifeLines Cohort Study 2022, ' Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals ', Nature Genetics, vol. 54, no. 4, pp. 437-449 . https://doi.org/10.1038/s41588-022-01016-z
Nature genetics, 54(4), 437-449. Nature Publishing Group
Nature Genetics
23Andme Research Team & Social Science Genetic Association Consortium 2022, ' Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals ', Nature genetics, vol. 54, no. 4, pp. 437-449 . https://doi.org/10.1038/s41588-022-01016-z
Nature Genetics, 54, 437-449
Nature Genetics, 54(4), 437-449. Nature Publishing Group
23andMe Research team, Social Science Genetic Association Consortium & Lifelines Cohort Study 2022, ' Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals ', Nature Genetics, vol. 54, no. 4, pp. 437-449 . https://doi.org/10.1038/s41588-022-01016-z
Okbay, A, Wu, Y, Wang, N, Jayashankar, H, Bennett, M, Nehzati, S M, Sidorenko, J, Kweon, H, Goldman, G, Gjorgjieva, T, Jiang, Y, Hicks, B, Tian, C, Hinds, D A, Ahlskog, R, Magnusson, P K E, Oskarsson, S, Hayward, C, Campbell, A, Porteous, D J, Freese, J, Herd, P, Agee, M, Alipanahi, B, Auton, A, Bell, R K, Bryc, K, Elson, S L, Fontanillas, P, Furlotte, N A, Hinds, D A, Huber, K E, Kleinman, A, Litterman, N K, McCreight, J C, McIntyre, M H, Mountain, J L, Northover, C A M, Pitts, S J, Sathirapongsasuti, J F, Sazonova, O V, Shelton, J F, Pers, T H, Timshel, P, Ahluwalia, T S, Bønnelykke, K, Bisgaard, H, Sørensen, T I A, 23andMe Research Team, Social Science Genetic Association Consortium & LifeLines Cohort Study 2022, ' Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals ', Nature Genetics, vol. 54, no. 4, pp. 437-449 . https://doi.org/10.1038/s41588-022-01016-z
Nature genetics, 54(4), 437-449. Nature Publishing Group
Nature Genetics
23Andme Research Team & Social Science Genetic Association Consortium 2022, ' Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals ', Nature genetics, vol. 54, no. 4, pp. 437-449 . https://doi.org/10.1038/s41588-022-01016-z
Nature Genetics, 54, 437-449
Nature Genetics, 54(4), 437-449. Nature Publishing Group
23andMe Research team, Social Science Genetic Association Consortium & Lifelines Cohort Study 2022, ' Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals ', Nature Genetics, vol. 54, no. 4, pp. 437-449 . https://doi.org/10.1038/s41588-022-01016-z
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of similar to 3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f0bbe92c3b9b0da9a12e7d0248be6c
https://www.pure.ed.ac.uk/ws/files/305359194/s41588_022_01016_z.pdf
https://www.pure.ed.ac.uk/ws/files/305359194/s41588_022_01016_z.pdf
Publikováno v:
The Journal of Infectious Diseases, 2002 Aug . 186(4), 447-452.
Externí odkaz:
https://www.jstor.org/stable/30084471
Autor:
Karlsson Linnér, Richard, Biroli, Pietro, Kong, Edward, Meddens, S. Fleur W., Wedow, Robbee, Fontana, Mark Alan, Lebreton, Maël, Tino, Stephen P., Abdellaoui, Abdel, Hammerschlag, Anke R., Nivard, Michel G., Okbay, Aysu, Rietveld, Cornelius A., Timshel, Pascal N., Trzaskowski, Maciej, Vlaming, Ronald de, Zünd, Christian L., Bao, Yanchun, Buzdugan, Laura, Caplin, Ann H., Chen, Chia-Yen, Eibich, Peter, Fontanillas, Pierre, Gonzalez, Juan R., Joshi, Peter K., Karhunen, Ville, Kleinman, Aaron, Levin, Remy Z., Lill, Christina M., Meddens, Gerardus A., Muntané, Gerard, Sanchez-Roige, Sandra, Rooij, Frank J. van, Taskesen, Erdogan, Yang, Wu, Zhang, Futao, Agee, Michelle, Alipanahi, Babak, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Furlotte, Nicholas A., Huber, Karen E., Litterman, Nadia K., Mccreight, Jennifer C., Mcintyre, Matthew H., Mountain, Joanna L., Northover, Carrie A. M., Pitts, Steven J., Sathirapongsasuti, J. Fah, Sazonova, Olga V., Shelton, Janie F., Shringarpure, Suyash, Tian, Chao, Tung, Joyce Y., Vacic, Vladimir, Wilson, Catherine H., Agbessi, Mawussé, Ahsan, Habibul, Alves, Isabel, Andiappan, Anand, Awadalla, Philip, Battle, Alexis, Beutner, Frank, Jan Bonder, Marc, Boomsma, Dorret I., Christiansen, Mark, Claringbould, Annique, Deelen, Patrick, Esko, Tõnu, Favé, Marie-Julie, Franke, Lude, Frayling, Timothy, Gharib, Sina A., Gibson, Gregory, Heijmans, Bastiaan, Hemani, Gibran, Jansen, Rick, Kähönen, Mika, Kalnapenkis, Anette, Kasela, Silva, Kettunen, Johannes, Kim, Yungil, Kirsten, Holger, Kovacs, Peter, Krohn, Knut, Kronberg-Guzman, Jaanika, Kukushkina, Viktorija, Kutalik, Zoltan, Lee, Bernett, Lehtimäki, Terho, Loeffler, Markus, Marigorta, Urko M., Metspalu, Andres, Milani, Lili, Montgomery, Grant W., Müller-Nurasyid, Martina, Nauck, Matthias, Penninx, Brenda, Perola, Markus, Pervjakova, Natalia, Pierce, Brandon, Powell, Joseph, Prokisch, Holger, Psaty, Bruce M., Raitakari, Olli, Ring, Susan, Ripatti, Samuli, Rotzchke, Olaf, Rüeger, Sina, Saha, Ashis, Scholz, Markus, Schramm, Katharina, Seppälä, Ilkka, Stumvoll, Michael, Sullivan, Patrick, Hoen, Peter-Bram t, Teumer, Alexander, Thiery, Joachim, Tong, Lin, Tönjes, Anke, Dongen, Jenny van, Meurs, Joyce van, Verlouw, Joost, Visscher, Peter M., Völker, Uwe, Võsa, Urmo, Westra, Harm-Jan, Yaghootkar, Hanieh, Yang, Jian, Zeng, Biao, Beauchamp, Jonathan P., Lee, James J., Pers, Tune H., Turley, Patrick, Chen, Guo-Bo, Emilsson, Valur, Oskarsson, Sven, Pickrell, Joseph K., Thom, Kevin, Timshel, Pascal, de Vlaming, Ronald, Ahluwalia, Tarunveer S., Bacelis, Jonas, Baumbach, Clemens, Bjornsdottir, Gyda, Brandsma, Johannes H., Concas, Maria Pina, Derringer, Jaime, Galesloot, Tessel E., Girotto, Giorgia, Gupta, Richa, Hall, Leanne M., Harris, Sarah E., Hofer, Edith, Horikoshi, Momoko, Huffman, Jennifer E., Kaasik, Kadri, Kalafati, Ioanna P., Karlsson, Robert, Kong, Augustine, Lahti, Jari, Lee, Sven J. van der, de Leeuw, Christiaan, Lind, Penelope A., Lindgren, Karl-Oskar, Liu, Tian, Mangino, Massimo, Marten, Jonathan, Mihailov, Evelin, Miller, Michael B., Most, Peter J. van der, Oldmeadow, Christopher, Payton, Antony, Peyrot, Wouter J., Qian, Yong, Rueedi, Rico, Salvi, Erika, Schmidt, Börge, Schraut, Katharina E., Shi, Jianxin, Smith, Albert V., Poot, Raymond A., Pourcain, Beate St, Thorleifsson, Gudmar, Verweij, Niek, Vuckovic, Dragana, Wellmann, Juergen, Yang, Jingyun, Zhao, Wei, Zhu, Zhihong, Alizadeh, Behrooz Z., Amin, Najaf, Bakshi, Andrew, Baumeister, Sebastian E., Biino, Ginevra, Bønnelykke, Klaus, Boyle, Patricia A., Campbell, Harry, Cappuccio, Francesco P., Davies, Gail, De Neve, Jan-Emmanuel, Deloukas, Panos, Demuth, Ilja, Ding, Jun, Eisele, Lewin, Eklund, Niina, Evans, David M., Faul, Jessica D., Feitosa, Mary F., Forstner, Andreas J., Gandin, Ilaria, Gunnarsson, Bjarni, Halldórsson, Bjarni V., Harris, Tamara B., Heath, Andrew C., Hocking, Lynne J., Holliday, Elizabeth G., Homuth, Georg, Horan, Michael A., Hottenga, Jouke-Jan, de Jager, Philip L., Jugessur, Astanand, Kaakinen, Marika A., Kanoni, Stavroula, Keltigangas-Järvinen, Liisa, Kiemeney, Lambertus A. L. M., Kolcic, Ivana, Koskinen, Seppo, Kraja, Aldi T., Kroh, Martin, Latvala, Antti, Launer, Lenore J., Lebreton, Maël P., Levinson, Douglas F., Lichtenstein, Paul, Lichtner, Peter, Liewald, David C. M., Loukola, Anu, Madden, Pamela A., Mägi, Reedik, Mäki-Opas, Tomi, Marioni, Riccardo E., Marques-Vidal, Pedro, Mcmahon, George, Meisinger, Christa, Meitinger, Thomas, Milaneschi, Yusplitri, Myhre, Ronny, Nelson, Christopher P., Nyholt, Dale R., Ollier, William E. R., Palotie, Aarno, Paternoster, Lavinia, Pedersen, Nancy L., Petrovic, Katja E., Porteous, David J., Räikkönen, Katri, Ring, Susan M., Robino, Antonietta, Rostapshova, Olga, Rudan, Igor, Rustichini, Aldo, Salomaa, Veikko, Sanders, Alan R., Sarin, Antti-Pekka, Schmidt, Helena, Scott, Rodney J., Smith, Blair H., Smith, Jennifer A., Staessen, Jan A., Steinhagen-Thiessen, Elisabeth, Strauch, Konstantin, Terracciano, Antonio, Tobin, Martin D., Ulivi, Sheila, Vaccargiu, Simona, Quaye, Lydia, Venturini, Cristina, Vinkhuyzen, Anna A. E., Völzke, Henry, Vonk, Judith M., Vozzi, Diego, Waage, Johannes, Ware, Erin B., Willemsen, Gonneke, Attia, John R., Bennett, David A., Berger, Klaus, Bertram, Lars, Bisgaard, Hans, Borecki, Ingrid B, Bültmann, Ute, Chabris, Christopher F., Cucca, Francesco, Cusi, Daniele, Deary, Ian J., Dedoussis, George V., Duijn, Cornelia M. van, Eriksson, Johan G., Franke, Barbara, Gasparini, Paolo, Gejman, Pablo V., Gieger, Christian, Grabe, Hans-Jörgen, Gratten, Jacob, Groenen, Patrick J. F., Gudnason, Vilmundur, Harst, Pim van der, Hayward, Caroline, Hinds, David A., Hoffmann, Wolfgang, Hyppönen, Elina, Iacono, William G., Jacobsson, Bo, Järvelin, Marjo-Riitta, Jöckel, Karl-Heinz, Kaprio, Jaakko, Kardia, Sharon L. R., Lehrer, Steven F., Magnusson, Patrik K. E., Martin, Nicholas G., Mcgue, Matt, Pendleton, Neil, Pirastu, Nicola, Pirastu, Mario, Polasek, Ozren, Posthuma, Danielle, Power, Christine, Province, Michael A., Samani, Nilesh J., Schlessinger, David, Schmidt, Reinhold, Sørensen, Thorkild I. A., Spector, Tim D., Stefansson, Kari, Thorsteinsdottir, Unnur, Thurik, A. Roy, Timpson, Nicholas J., Tiemeier, Henning, Uitterlinden, André G., Vitart, Veronique, Vollenweider, Peter, Weir, David R., Wilson, James F., Wright, Alan F., Conley, Dalton C., Krueger, Robert F., Smith, George Davey, Hofman, Albert, Laibson, David I., Medland, Sarah E., Meyer, Michelle N., Johannesson, Magnus, Koellinger, Philipp D., Cesarini, David, Benjamin, Daniel J., Auton, Adam, Boardman, Jason D., Clark, David W., Conlin, Andrew, Dolan, Conor C., Fischbacher, Urs, Harris, Kathleen Mullan, Hasler, Gregor, Ikram, Mohammad A., Jain, Sonia, Kessler, Ronald C., Kooyman, Maarten, Mackillop, James, Männikkö, Minna, Morcillo-Suarez, Carlos, Mcqueen, Matthew B., Schmidt, Klaus M., Smart, Melissa C., Sutter, Matthias, White, Jon, Wit, Harriet de, Fehr, Ernst, Kumari, Meena, Laibson, David, Navarro, Arcadi, Palmer, Abraham A., Schunk, Daniel, Stein, Murray B., Svento, Rauli, Timmers, Paul R. H. J., Ursano, Robert J., Wagner, Gert G.
Publikováno v:
2019, ' Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences ', Nature Genetics . https://doi.org/10.1038/s41588-018-0309-3
Nature Genetics, 51, 2, pp. 245-257
Nature genetics, 51(2), 245-257. Nature Publishing Group
Nature Genetics, 51(2), 245-257. Nature Publishing Group
Nature Genetics
Karlsson Linnér, R, Biroli, P, Kong, E, Meddens, S F W, Wedow, R, Fontana, M A, Lebreton, M, Tino, S P, Abdellaoui, A, Hammerschlag, A R, Nivard, M G, Okbay, A, Rietveld, C A, Timshel, P N, Trzaskowski, M, Vlaming, R D, Zünd, C L, Bao, Y, Buzdugan, L, Caplin, A H, Chen, C-Y, Eibich, P, Fontanillas, P, Gonzalez, J R, Joshi, P K, Karhunen, V, Kleinman, A, Levin, R Z, Lill, C M, Meddens, G A, Muntané, G, Sanchez-Roige, S, Rooij, F J V, Taskesen, E, Wu, Y, Jansen, R, Penninx, B, Peyrot, W J, Evans, D M, Milaneschi, Y, Posthuma, D, 23and Me Research Team, Schunk, D, Stein, M B, Svento, R, Tiemeier, H, Timmers, P R H J, Turley, P, Ursano, R J, Wagner, G G, Wilson, J F, Gratten, J, Lee, J J, Cesarini, D, Benjamin, D J, Koellinger, P D & Beauchamp, J P 2019, ' Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences ', Nature Genetics, vol. 51, no. 2, pp. 245-257 . https://doi.org/10.1038/s41588-018-0309-3
Nature Genetics, 51, 245-257
Social Science Genetic Association Consortium, 23and Me Research Team, eQTLGen Consortium & International Cannabis Consortium 2019, ' Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences ', Nature Genetics, vol. 51, no. 2, pp. 245-257 . https://doi.org/10.1038/s41588-018-0309-3
Nature Genetics, 51(2), 245
Nature Genetics, 51(2), 245-+. Nature Publishing Group
23and Me Research Team & Pendleton, N 2019, ' Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences ', Nature Genetics . https://doi.org/10.1038/s41588-018-0309-3
Nat. Genet. 51, 245-257 (2019)
Nature Genetics, 51, 2, pp. 245-257
Nature genetics, 51(2), 245-257. Nature Publishing Group
Nature Genetics, 51(2), 245-257. Nature Publishing Group
Nature Genetics
Karlsson Linnér, R, Biroli, P, Kong, E, Meddens, S F W, Wedow, R, Fontana, M A, Lebreton, M, Tino, S P, Abdellaoui, A, Hammerschlag, A R, Nivard, M G, Okbay, A, Rietveld, C A, Timshel, P N, Trzaskowski, M, Vlaming, R D, Zünd, C L, Bao, Y, Buzdugan, L, Caplin, A H, Chen, C-Y, Eibich, P, Fontanillas, P, Gonzalez, J R, Joshi, P K, Karhunen, V, Kleinman, A, Levin, R Z, Lill, C M, Meddens, G A, Muntané, G, Sanchez-Roige, S, Rooij, F J V, Taskesen, E, Wu, Y, Jansen, R, Penninx, B, Peyrot, W J, Evans, D M, Milaneschi, Y, Posthuma, D, 23and Me Research Team, Schunk, D, Stein, M B, Svento, R, Tiemeier, H, Timmers, P R H J, Turley, P, Ursano, R J, Wagner, G G, Wilson, J F, Gratten, J, Lee, J J, Cesarini, D, Benjamin, D J, Koellinger, P D & Beauchamp, J P 2019, ' Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences ', Nature Genetics, vol. 51, no. 2, pp. 245-257 . https://doi.org/10.1038/s41588-018-0309-3
Nature Genetics, 51, 245-257
Social Science Genetic Association Consortium, 23and Me Research Team, eQTLGen Consortium & International Cannabis Consortium 2019, ' Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences ', Nature Genetics, vol. 51, no. 2, pp. 245-257 . https://doi.org/10.1038/s41588-018-0309-3
Nature Genetics, 51(2), 245
Nature Genetics, 51(2), 245-+. Nature Publishing Group
23and Me Research Team & Pendleton, N 2019, ' Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences ', Nature Genetics . https://doi.org/10.1038/s41588-018-0309-3
Nat. Genet. 51, 245-257 (2019)
Humans vary substantially in their willingness to take risks. In a combined sample of over 1 million individuals, we conducted genome-wide association studies (GWAS) of general risk tolerance, adventurousness, and risky behaviors in the driving, drin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb25f7df9dc9de71b0dd890021c2c33e
https://hdl.handle.net/20.500.11820/06269f4b-2576-47bd-af50-3f97e6c9f2cb
https://hdl.handle.net/20.500.11820/06269f4b-2576-47bd-af50-3f97e6c9f2cb
Akademický článek
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Autor:
Lee, James J., Wedow, Robbee, Okbay, Aysu, Kong, Edward, Maghzian, Omeed, Zacher, Meghan, Nguyen-Viet, Tuan Anh, Bowers, Peter, Sidorenko, Julia, Karlsson Linnér, Richard, Fontana, Mark Alan, Kundu, Tushar, Lee, Chanwook, Hui, Li, Ruoxi, Li, Royer, Rebecca, Timshel, Pascal N., Walters, Raymond K., Willoughby, Emily A., Yengo, Loïc, Agee, Michelle, Alipanahi, Babak, Auton, Adam, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Fontanillas, Pierre, Hinds, David A., Mccreight, Jennifer C., Huber, Karen E., Litterman, Nadia K., Mcintyre, Matthew H., Mountain, Joanna L., Noblin, Elizabeth S., Northover, Carrie A. M., Pitts, Steven J., Sathirapongsasuti, J. Fah, Sazonova, Olga V., Shelton, Janie F., Shringarpure, Suyash, Tian, Chao, Vacic, Vladimir, Wilson, Catherine H., Beauchamp, Jonathan P., Pers, Tune H., Rietveld, Cornelius A., Turley, Patrick, Chen, Guo-Bo, Emilsson, Valur, Meddens, S. Fleur W., Oskarsson, Sven, Pickrell, Joseph K., Thom, Kevin, Timshel, Pascal, Vlaming, Ronald de, Abdellaoui, Abdel, Ahluwalia, Tarunveer S., Bacelis, Jonas, Baumbach, Clemens, Bjornsdottir, Gyda, Brandsma, Johannes H., Concas, Maria Pina, Derringer, Jaime, Furlotte, Nicholas A., Galesloot, Tessel E., Girotto, Giorgia, Gupta, Richa, Hall, Leanne M., Harris, Sarah E., Hofer, Edith, Horikoshi, Momoko, Huffman, Jennifer E., Kaasik, Kadri, Kalafati, Ioanna P., Karlsson, Robert, Kong, Augustine, Lahti, Jari, van der Lee, Sven J., Leeuw, Christiaan de, Lind, Penelope A., Lindgren, Karl-Oskar, Liu, Tian, Mangino, Massimo, Marten, Jonathan, Mihailov, Evelin, Miller, Michael B., van der Most, Peter J., Oldmeadow, Christopher, Payton, Antony, Pervjakova, Natalia, Peyrot, Wouter J., Qian, Yong, Raitakari, Olli, Rueedi, Rico, Salvi, Erika, Schmidt, Börge, Schraut, Katharina E., Shi, Jianxin, Smith, Albert V., Poot, Raymond A., St Pourcain, Beate, Teumer, Alexander, Thorleifsson, Gudmar, Verweij, Niek, Vuckovic, Dragana, Wellmann, Juergen, Westra, Harm-Jan, Yang, Jingyun, Zhao, Wei, Zhu, Zhihong, Alizadeh, Behrooz Z., Amin, Najaf, Bakshi, Andrew, Baumeister, Sebastian E., Biino, Ginevra, Bønnelykke, Klaus, Boyle, Patricia A., Campbell, Harry, Cappuccio, Francesco P., Davies, Gail, De Neve, Jan-Emmanuel, Deloukas, Panos, Demuth, Ilja, Ding, Jun, Eibich, Peter, Eisele, Lewin, Eklund, Niina, Evans, David M., Faul, Jessica D., Feitosa, Mary F., Forstner, Andreas J., Gandin, Ilaria, Gunnarsson, Bjarni, Halldórsson, Bjarni V., Harris, Tamara B., Heath, Andrew C., Hocking, Lynne J., Holliday, Elizabeth G., Homuth, Georg, Horan, Michael A., Hottenga, Jouke-Jan, de Jager, Philip L., Joshi, Peter K., Jugessur, Astanand, Kaakinen, Marika A., Kähönen, Mika, Kanoni, Stavroula, Keltigangas-Järvinen, Liisa, Kiemeney, Lambertus A. L. M., Kolcic, Ivana, Koskinen, Seppo, Kraja, Aldi T., Kroh, Martin, Kutalik, Zoltan, Latvala, Antti, Launer, Lenore J., Lebreton, Maël P., Levinson, Douglas F., Lichtenstein, Paul, Lichtner, Peter, Liewald, David C. M., Loukola, LifeLines Cohort Study, Anu, Madden, Pamela A., Mägi, Reedik, Mäki-Opas, Tomi, Marioni, Riccardo E., Marques-Vidal, Pedro, Meddens, Gerardus A., Mcmahon, George, Meisinger, Christa, Meitinger, Thomas, Milaneschi, Yusplitri, Milani, Lili, Montgomery, Grant W., Myhre, Ronny, Nelson, Christopher P., Nyholt, Dale R., Ollier, William E. R., Palotie, Aarno, Paternoster, Lavinia, Pedersen, Nancy L., Petrovic, Katja E., Porteous, David J., Räikkönen, Katri, Ring, Susan M., Robino, Antonietta, Rostapshova, Olga, Rudan, Igor, Rustichini, Aldo, Salomaa, Veikko, Sanders, Alan R., Sarin, Antti-Pekka, Schmidt, Helena, Scott, Rodney J., Smith, Blair H., Smith, Jennifer A., Staessen, Jan A., Steinhagen-Thiessen, Elisabeth, Strauch, Konstantin, Terracciano, Antonio, Tobin, Martin D., Ulivi, Sheila, Vaccargiu, Simona, Quaye, Lydia, van Rooij, Frank J. A., Venturini, Cristina, Vinkhuyzen, Anna A. E., Völker, Uwe, Völzke, Henry, Vonk, Judith M., Vozzi, Diego, Waage, Johannes, Ware, Erin B., Willemsen, Gonneke, Attia, John R., Bennett, David A., Berger, Klaus, Bertram, Lars, Bisgaard, Hans, Boomsma, Dorret I., Borecki, Ingrid B., Bültmann, Ute, Chabris, Christopher F., Cucca, Francesco, Cusi, Daniele, Deary, Ian J., Dedoussis, George V., van Duijn, Cornelia M., Eriksson, Johan G., Franke, Barbara, Franke, Lude, Gasparini, Paolo, Gejman, Pablo V., Gieger, Christian, Grabe, Hans-Jörgen, Gratten, Jacob, Groenen, Patrick J. F., Gudnason, Vilmundur, van der Harst, Pim, Hayward, Caroline, Hoffmann, Wolfgang, Hyppönen, Elina, Iacono, William G., Jacobsson, Bo, Järvelin, Marjo-Riitta, Jöckel, Karl-Heinz, Kaprio, Jaakko, Kardia, Sharon L. R., Lehtimäki, Terho, Lehrer, Steven F., Magnusson, Patrik K. E., Martin, Nicholas G., Mcgue, Matt, Metspalu, Andres, Pendleton, Neil, Penninx, Brenda W. J. H., Perola, Markus, Pirastu, Nicola, Pirastu, Mario, Polasek, Ozren, Posthuma, Danielle, Power, Christine, Province, Michael A., Samani, Nilesh J., Schlessinger, David, Schmidt, Reinhold, Sørensen, Thorkild I. A., Spector, Tim D., Stefansson, Kari, Thorsteinsdottir, Unnur, Thurik, A. Roy, Timpson, Nicholas J., Tiemeier, Henning, Tung, Joyce Y., Uitterlinden, André G., Vitart, Veronique, Vollenweider, Peter, Weir, David R., Wilson, James F., Wright, Alan F., Conley, Dalton C., Krueger, Robert F., Smith, George Davey, Hofman, Albert, Laibson, David I., Medland, Sarah E., Meyer, Michelle N., Yang, Jian, Johannesson, Magnus, Visscher, Peter M., Esko, Tõnu, Koellinger, Philipp D., Cesarini, David, Benjamin, Daniel J., Alver, Maris, Bao, Yanchun, Clark, David W., Day, Felix R., Kemper, Kathryn E., Kleinman, Aaron, Langenberg, Claudia, Trampush, Joey W., Verma, Shefali Setia, Yang, Wu, Lam, Max, Zhao, Jing Hua, Zheng, Zhili, Boardman, Jason D., Freese, Jeremy, Harris, Kathleen Mullan, Herd, Pamela, Kumari, Meena, Lencz, Todd, Luan, Jian’An, Malhotra, Anil K., Ong, Ken K., Perry, John R. B., Ritchie, Marylyn D., Smart, Melissa C., Wareham, Nicholas J., Robinson, Matthew R., Watson, Chelsea
Publikováno v:
Nat. Genet. 52, 1112-1121 (2018)
Nature Genetics
Nature Genetics, 50(8), 1112-1121. Nature Publishing Group
23Andme Research Team, Abdellaoui, A, Peyrot, W J, Hottenga, J J, Vinkhuyzen, A A E, Willemsen, G, Boomsma, D I, van Duijn, C M, Penninx, B, Posthuma, D & Uitterlinden, A G 2018, ' Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals ', Nature Genetics, vol. 50, no. 8, pp. 1112-1121 . https://doi.org/10.1038/s41588-018-0147-3
Nature Genetics, 50, 1112-1121
2018, ' Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals ', Nature Genetics, vol. 50, no. 8, pp. 1112-+ . https://doi.org/10.1038/s41588-018-0147-3
Nature genetics, 50(8), 1112-1121. Nature Publishing Group
Nature Genetics, 50, 8, pp. 1112-1121
Nature Genetics, 50(8), 1112-+. Nature Publishing Group
23andMe Research team 2018, ' Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals ', Nature Genetics, vol. 50, no. 8, pp. 1112-1121 . https://doi.org/10.1038/s41588-018-0147-3
23andMe Research Team & Pendleton, N 2018, ' Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals ', Nature Genetics, vol. 50, no. 8, pp. 1112-1121 . https://doi.org/10.1038/s41588-018-0147-3
Nature Genetics
Nature Genetics, 50(8), 1112-1121. Nature Publishing Group
23Andme Research Team, Abdellaoui, A, Peyrot, W J, Hottenga, J J, Vinkhuyzen, A A E, Willemsen, G, Boomsma, D I, van Duijn, C M, Penninx, B, Posthuma, D & Uitterlinden, A G 2018, ' Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals ', Nature Genetics, vol. 50, no. 8, pp. 1112-1121 . https://doi.org/10.1038/s41588-018-0147-3
Nature Genetics, 50, 1112-1121
2018, ' Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals ', Nature Genetics, vol. 50, no. 8, pp. 1112-+ . https://doi.org/10.1038/s41588-018-0147-3
Nature genetics, 50(8), 1112-1121. Nature Publishing Group
Nature Genetics, 50, 8, pp. 1112-1121
Nature Genetics, 50(8), 1112-+. Nature Publishing Group
23andMe Research team 2018, ' Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals ', Nature Genetics, vol. 50, no. 8, pp. 1112-1121 . https://doi.org/10.1038/s41588-018-0147-3
23andMe Research Team & Pendleton, N 2018, ' Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals ', Nature Genetics, vol. 50, no. 8, pp. 1112-1121 . https://doi.org/10.1038/s41588-018-0147-3
Contains fulltext : 195595.pdf (Publisher’s version ) (Open Access) Here we conducted a large-scale genetic association analysis of educational attainment in a sample of approximately 1.1 million individuals and identify 1,271 independent genome-wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d23aa9d89404a0315f7a0c671918a03
https://doi.org/10.1038/s41588-018-0147-3
https://doi.org/10.1038/s41588-018-0147-3
Autor:
Acosta-Herrera, Marialbert, Kerick, Martin, González-Serna, David, Wijmenga, Cisca, Franke, Andre, Gregersen, Peter K., Padyukov, Leonid, Worthington, J., Vyse, T. J., Alarcón-Riquelme, M. E., Mayes, M. D., Martín, J., Miller, Frederick W., Chen, Wei, O'Hanlon, Terrance P., Cooper, Robert G., Vencovsky, Jiri, Rider, Lisa G, Danko, Katalin, Wedderburn, Lucy R., Lundberg, Ingrid E., Pachman, Lauren M., Reed, Ann M., Ytterberg, Steven R, Selva-O'Callaghan, Alber, Radstake, Timothy R., Isenberg, David A, Chinoy, Hector, Ollier, William E. R, Scheet, Paul, Peng, Bo, Lee, Annette, Lamb, Janine A., Amos, Christopher I., Denton, Christopher, Hilton-Jones, David, Plotz, Paul H., Varsani, Hemlata, Radstake, Timothy R. D. J., Gorlova, Olga, Rueda, B., Martín, J. E., Alizadeh, B. Z., Palomino-Morales, Rogelio, Coenen, Marieke J. H., Vonk, Madelon C., Voskuyl, Alexandre E., Scheurwegh, Annemie J., Broen, Jasper C., van Riel, Piet L. C. M., van 't Slot, Rubén, Italiaander, Annet, Ophoff, Roel A., Riemekasten, Gabriela, Hunzelmann, Nicolas, Simeon, Carmen P., Ortego-Centeno, N., González-Gay, M. A., González-Escribano, María Francisca, Airó, Paolo, van Laar, Jaap, Herrick, Ariane L., Hesselstrand, Roger, Smith, Vanessa, de Keyser, Filip, Houssiau, Fredric, Chee, Meng May, Madhok, Rajan, Shiels, Paul, Westhovens, Rene, Kreuter, A., Kiener, Hans, de Baere, Elfride, Witte, Torsten, Klareskog, Lars, Beretta, Lorenzo, Scorza, Rafaella, Lie, Benedicte A., Hoffman-Vold, A. M., Carreira, P., Varga, John, Hinchcliff, Monique, Lee, Annette T., Ying, Jun, Han, Younghun, Weng, Shih-Feng, Wigley, Fredrick M., Hummers, L. K., Nelson, J. Lee, Agarwal, Sandeep K., Assassi, S., Gourh, Pravitt, Tan, Filemon K., Koeleman, B. P., Arnett, Frank C., Myositis Genetics Consortium, Scleroderma Genetics Consortium.
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Acosta-Herrera, M, Kerick, M, Gonzalez-Serna, D, Wijmenga, C, Franke, A, Gregersen, P K, Padyukov, L, Worthington, J, Vyse, T, Alarcón-Riquelme, M E, Mayes, M D & Martin, J 2019, ' Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases ', Annals Of Rheumatic Diseases, vol. 78, pp. 311-319 . https://doi.org/10.1136/annrheumdis-2018-214127
Annals of the rheumatic diseases, vol 78, iss 3
Annals of the Rheumatic Diseases, 78, 3, pp. 311-319
Annals of the Rheumatic Diseases, 78, 311-319
Annals of the Rheumatic Diseases, 78(3), 311-319. BMJ PUBLISHING GROUP
Annals of the rheumatic diseases
instname
Acosta-Herrera, M, Kerick, M, Gonzalez-Serna, D, Wijmenga, C, Franke, A, Gregersen, P K, Padyukov, L, Worthington, J, Vyse, T, Alarcón-Riquelme, M E, Mayes, M D & Martin, J 2019, ' Genome-wide meta-analysis reveals shared new loci in systemic seropositive rheumatic diseases ', Annals Of Rheumatic Diseases, vol. 78, pp. 311-319 . https://doi.org/10.1136/annrheumdis-2018-214127
Annals of the rheumatic diseases, vol 78, iss 3
Annals of the Rheumatic Diseases, 78, 3, pp. 311-319
Annals of the Rheumatic Diseases, 78, 311-319
Annals of the Rheumatic Diseases, 78(3), 311-319. BMJ PUBLISHING GROUP
Annals of the rheumatic diseases
ObjectiveImmune-mediated inflammatory diseases (IMIDs) are heterogeneous and complex conditions with overlapping clinical symptoms and elevated familial aggregation, which suggests the existence of a shared genetic component. In order to identify thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::840aa90000136e8bcda9414e9db777db
http://hdl.handle.net/10261/200275
http://hdl.handle.net/10261/200275
Akademický článek
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Autor:
Joshi, Peter K., Pirastu, Nicola, Kentistou, Katherine A., Fischer, Krista, Hofer, Edith, Schraut, Katharina E., Clark, David W., Nutile, Teresa, Barnes, Catriona L. K., Timmers, Paul R. H. J., Shen, Xia, Gandin, Ilaria, McDaid, Aaron F., Hansen, Thomas Folkmann, Gordon, Scott D., Giulianini, Franco, Boutin, Thibaud S., Abdellaoui, Abdel, Zhao, Wei, Medina-Gomez, Carolina, Bartz, Traci M., Trompet, Stella, Lange, Leslie A., Raffield, Laura, van der Spek, Ashley, Galesloot, Tessel E., Proitsi, Petroula, Yanek, Lisa R., Bielak, Lawrence F., Payton, Antony, Murgia, Federico, Concas, Maria Pina, Biino, Ginevra, Tajuddin, Salman M., Seppälä, Ilkka, Amin, Najaf, Boerwinkle, Eric, Børglum, Anders D., Campbell, Archie, Demerath, Ellen W., Demuth, Ilja, Faul, Jessica D., Ford, Ian, Gialluisi, Alessandro, Gögele, Martin, Graff, MariaElisa, Hingorani, Aroon, Hottenga, Jouke-Jan, Hougaard, David M., Hurme, Mikko A., Ikram, M. Arfan, Jylhä, Marja, Kuh, Diana, Ligthart, Lannie, Lill, Christina M., Lindenberger, Ulman, Lumley, Thomas, Mägi, Reedik, Marques-Vidal, Pedro, Medland, Sarah E., Milani, Lili, Nagy, Reka, Ollier, William E. R., Peyser, Patricia A., Pramstaller, Peter P., Ridker, Paul M., Rivadeneira, Fernando, Ruggiero, Daniela, Saba, Yasaman, Schmidt, Reinhold, Schmidt, Helena, Slagboom, P. Eline, Smith, Blair H., Smith, Jennifer A., Sotoodehnia, Nona, Steinhagen-Thiessen, Elisabeth, van Rooij, Frank J. A., Verbeek, André L., Vermeulen, Sita H., Vollenweider, Peter, Wang, Yunpeng, Werge, Thomas, Whitfield, John B., Zonderman, Alan B., Lehtimäki, Terho, Evans, Michele K., Pirastu, Mario, Fuchsberger, Christian, Bertram, Lars, Pendleton, Neil, Kardia, Sharon L. R., Ciullo, Marina, Becker, Diane M., Wong, Andrew, Psaty, Bruce M., van Duijn, Cornelia M., Wilson, James G., Jukema, J. Wouter, Kiemeney, Lambertus, Uitterlinden, André G., Franceschini, Nora, North, Kari E., Weir, David R., Metspalu, Andres, Boomsma, Dorret I., Hayward, Caroline, Chasman, Daniel, Martin, Nicholas G., Sattar, Naveed, Campbell, Harry, Esko, Tōnu, Kutalik, Zoltán, Wilson, James F.
Publikováno v:
Nature Communications, 8:910. Nature Publishing Group
Nature Communications
Nature Communications, 8(1):910. Nature Publishing Group
Joshi, P K, Pirastu, N, Kentistou, K A, Fischer, K, Hofer, E, Schraut, K E, Clark, D W, Nutile, T, Barnes, C L K, Timmers, P R H J, Shen, X, Gandin, I, McDaid, A F, Hansen, T F, Gordon, S D, Giulianini, F, Boutin, T S, Abdellaoui, A, Zhao, W, Medina-Gomez, C, Bartz, T M, Trompet, S, Lange, L A, Raffield, L, van der Spek, A, Galesloot, T E, Proitsi, P, Yanek, L R, Bielak, L F, Payton, A, Murgia, F, Concas, M P, Biino, G, Tajuddin, S M, Seppälä, I, Amin, N, Boerwinkle, E, Børglum, A D, Campbell, A, Demerath, E W, Demuth, I, Faul, J D, Ford, I, Gialluisi, A, Gögele, M, Graff, M, Hingorani, A, Hottenga, J-J, Hougaard, D M, Hurme, M A, Ikram, M A, Jylhä, M, Kuh, D, Ligthart, L, Lill, C M, Lindenberger, U, Lumley, T, Mägi, R, Marques-Vidal, P, Medland, S E, Milani, L, Nagy, R, Ollier, W E R, Peyser, P A, Pramstaller, P P, Ridker, P M, Rivadeneira, F, Ruggiero, D, Saba, Y, Schmidt, R, Schmidt, H, Slagboom, P E, Smith, B H, Smith, J A, Sotoodehnia, N, Steinhagen-Thiessen, E, van Rooij, F J A, Verbeek, A L, Vermeulen, S H, Vollenweider, P, Wang, Y, Werge, T, Whitfield, J B, Zonderman, A B, Lehtimäki, T, Evans, M K, Pirastu, M, Fuchsberger, C, Bertram, L, Pendleton, N, Kardia, S L R, Ciullo, M, Becker, D M, Wong, A, Psaty, B M, van Duijn, C M, Wilson, J G, Jukema, J W, Kiemeney, L, Uitterlinden, A G, Franceschini, N, North, K E, Weir, D R, Metspalu, A, Boomsma, D I, Hayward, C, Chasman, D, Martin, N G, Sattar, N, Campbell, H, Esko, T, Kutalik, Z & Wilson, J G 2017, ' Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity ', Nature Communications, vol. 8, no. 1, 910 . https://doi.org/10.1038/s41467-017-00934-5
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications, 8
Joshi, P K, Pirastu, N, Kentistou, K A, Fischer, K, Hofer, E, Schraut, K E, Clark, D W, Nutile, T, Barnes, C L K, Timmers, P R H J, Shen, X, Gandin, I, McDaid, A F, Hansen, T F, Gordon, S D, Giulianini, F, Boutin, T S, Abdellaoui, A, Zhao, W, Medina-Gomez, C, Bartz, T M, Trompet, S, Lange, L A, Raffield, L, van der Spek, A, Galesloot, T E, Proitsi, P, Yanek, L R, Bielak, L F, Payton, A, Murgia, F, Concas, M P, Biino, G, Tajuddin, S M, Seppälä, I, Amin, N, Boerwinkle, E, Børglum, A D, Campbell, A, Demerath, E W, Demuth, I, Faul, J D, Ford, I, Gialluisi, A, Gögele, M, Graff, M, Hingorani, A, Hottenga, J-J, Hougaard, D M, Hurme, M A, Ikram, M A, Jylhä, M, Kuh, D, Ligthart, L, Lill, C M, Lindenberger, U, Lumley, T, Mägi, R, Marques-Vidal, P, Medland, S E, Milani, L, Nagy, R, Ollier, W E R, Peyser, P A, Pramstaller, P P, Ridker, P M, Rivadeneira, F, Ruggiero, D, Saba, Y, Schmidt, R, Schmidt, H, Slagboom, P E, Smith, B H, Smith, J A, Sotoodehnia, N, Steinhagen-Thiessen, E, van Rooij, F J A, Verbeek, A L, Vermeulen, S H, Vollenweider, P, Wang, Y, Werge, T, Whitfield, J B, Zonderman, A B, Lehtimäki, T, Evans, M K, Pirastu, M, Fuchsberger, C, Bertram, L, Pendleton, N, Kardia, S L R, Ciullo, M, Becker, D M, Wong, A, Psaty, B M, van Duijn, C M, Wilson, J G, Jukema, J W, Kiemeney, L, Uitterlinden, A G, Franceschini, N, North, K E, Weir, D R, Metspalu, A, Boomsma, D I, Hayward, C, Chasman, D, Martin, N G, Sattar, N, Campbell, H, Esko, T, Kutalik, Z & Wilson, J F 2017, ' Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity ', Nature Communications, vol. 8, 910 . https://doi.org/10.1038/s41467-017-00934-5
Joshi, P K, Pirastu, N, Kentistou, K A, Fischer, K, Hofer, E, Schraut, K E, Clark, D W, Nutile, T, Barnes, C L K, Timmers, P R H J, Shen, X, Gandin, I, McDaid, A F, Hansen, T F, Gordon, S D, Giulianini, F, Boutin, T S, Abdellaoui, A, Zhao, W, Medina-Gomez, C, Bartz, T M, Trompet, S, Lange, L A, Raffield, L, van der Spek, A, Galesloot, T E, Proitsi, P, Yanek, L R, Bielak, L F, Payton, A, Murgia, F, Concas, M P, Biino, G, Tajuddin, S M, Seppälä, I, Amin, N, Boerwinkle, E, Børglum, A D, Campbell, A, Demerath, E W, Demuth, I, Faul, J D, Ford, I, Gialluisi, A, Gögele, M, Graff, M, Hingorani, A, Hottenga, J-J, Hougaard, D M, Hurme, M A, Ikram, M A, Jylhä, M, Kuh, D, Ligthart, L, Lill, C M, Lindenberger, U, Lumley, T, Mägi, R, Marques-Vidal, P, Medland, S E, Milani, L, Nagy, R, Ollier, W E R, Peyser, P A, Pramstaller, P P, Ridker, P M, Rivadeneira, F, Ruggiero, D, Saba, Y, Schmidt, R, Schmidt, H, Slagboom, P E, Smith, B H, Smith, J A, Sotoodehnia, N, Steinhagen-Thiessen, E, van Rooij, F J A, Verbeek, A L, Vermeulen, S H, Vollenweider, P, Wang, Y, Werge, T, Whitfield, J B, Zonderman, A B, Lehtimäki, T, Evans, M K, Pirastu, M, Fuchsberger, C, Bertram, L, Pendleton, N, Kardia, S L R, Ciullo, M, Becker, D M, Wong, A, Psaty, B M, van Duijn, C M, Wilson, J G, Jukema, J W, Kiemeney, L, Uitterlinden, A G, Franceschini, N, North, K E, Weir, D R, Metspalu, A, Boomsma, D I, Hayward, C, Chasman, D, Martin, N G, Sattar, N, Campbell, H, Esko, T, Kutalik, Z & Wilson, J F 2017, ' Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity ', Nature Communications, vol. 8, no. 1, 910, pp. 910 . https://doi.org/10.1038/s41467-017-00934-5
Nature communications, vol. 8, no. 1, pp. 910
Joshi, P K, Pirastu, N, Kentistou, K A, Fischer, K, Hofer, E, Schraut, K E, Clark, D W, Nutile, T, Barnes, C L K, Timmers, P R H J, Shen, X, Gandin, I, Mcdaid, A F, Hansen, T F, Gordon, S D, Giulianini, F, Boutin, T S, Abdellaoui, A, Zhao, W, Medina-Gomez, C, Bartz, T M, Trompet, S, Lange, L A, Raffield, L, van der Spek, A, Galesloot, T E, Proitsi, P, Yanek, L R, Bielak, L F, Payton, A, Murgia, F, Concas, M P, Biino, G, Tajuddin, S M, Seppälä, I, Amin, N, Boerwinkle, E, Børglum, A D, Campbell, A, Demerath, E W, Demuth, I, Faul, J D, Ford, I, Gialluisi, A, Gögele, M, Graff, M, Hingorani, A, Hottenga, J-J, Hougaard, D M, Hurme, M A, Ikram, M A, Jylhä, M, Kuh, D, Ligthart, L, Lill, C M, Lindenberger, U, Lumley, T, Mägi, R, Marques-Vidal, P, Medland, S E, Milani, L, Nagy, R, Ollier, W E R, Peyser, P A, Pramstaller, P P, Ridker, P M, Rivadeneira, F, Ruggiero, D, Saba, Y, Schmidt, R, Schmidt, H, Slagboom, P E, Smith, B H, Smith, J A, Sotoodehnia, N, Steinhagen-Thiessen, E, van Rooij, F J A, Verbeek, A L, Vermeulen, S H, Vollenweider, P, Wang, Y, Werge, T, Whitfield, J B, Zonderman, A B, Lehtimäki, T, Evans, M K, Pirastu, M, Fuchsberger, C, Bertram, L, Pendleton, N, Kardia, S L R, Ciullo, M, Becker, D M, Wong, A, Psaty, B M, van Duijn, C M, Wilson, J G, Jukema, J W, Kiemeney, L, Uitterlinden, A G, Franceschini, N, North, K E, Weir, D R, Metspalu, A, Boomsma, D I, Hayward, C, Chasman, D, Martin, N G, Sattar, N, Campbell, H, Esko, T, Kutalik, Z & Wilson, J F 2017, ' Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity ', Nature Communications, vol. 8, 910 . https://doi.org/10.1038/s41467-017-00934-5
Nature Communications
Nature Communications, 8(1):910. Nature Publishing Group
Joshi, P K, Pirastu, N, Kentistou, K A, Fischer, K, Hofer, E, Schraut, K E, Clark, D W, Nutile, T, Barnes, C L K, Timmers, P R H J, Shen, X, Gandin, I, McDaid, A F, Hansen, T F, Gordon, S D, Giulianini, F, Boutin, T S, Abdellaoui, A, Zhao, W, Medina-Gomez, C, Bartz, T M, Trompet, S, Lange, L A, Raffield, L, van der Spek, A, Galesloot, T E, Proitsi, P, Yanek, L R, Bielak, L F, Payton, A, Murgia, F, Concas, M P, Biino, G, Tajuddin, S M, Seppälä, I, Amin, N, Boerwinkle, E, Børglum, A D, Campbell, A, Demerath, E W, Demuth, I, Faul, J D, Ford, I, Gialluisi, A, Gögele, M, Graff, M, Hingorani, A, Hottenga, J-J, Hougaard, D M, Hurme, M A, Ikram, M A, Jylhä, M, Kuh, D, Ligthart, L, Lill, C M, Lindenberger, U, Lumley, T, Mägi, R, Marques-Vidal, P, Medland, S E, Milani, L, Nagy, R, Ollier, W E R, Peyser, P A, Pramstaller, P P, Ridker, P M, Rivadeneira, F, Ruggiero, D, Saba, Y, Schmidt, R, Schmidt, H, Slagboom, P E, Smith, B H, Smith, J A, Sotoodehnia, N, Steinhagen-Thiessen, E, van Rooij, F J A, Verbeek, A L, Vermeulen, S H, Vollenweider, P, Wang, Y, Werge, T, Whitfield, J B, Zonderman, A B, Lehtimäki, T, Evans, M K, Pirastu, M, Fuchsberger, C, Bertram, L, Pendleton, N, Kardia, S L R, Ciullo, M, Becker, D M, Wong, A, Psaty, B M, van Duijn, C M, Wilson, J G, Jukema, J W, Kiemeney, L, Uitterlinden, A G, Franceschini, N, North, K E, Weir, D R, Metspalu, A, Boomsma, D I, Hayward, C, Chasman, D, Martin, N G, Sattar, N, Campbell, H, Esko, T, Kutalik, Z & Wilson, J G 2017, ' Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity ', Nature Communications, vol. 8, no. 1, 910 . https://doi.org/10.1038/s41467-017-00934-5
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications, 8
Joshi, P K, Pirastu, N, Kentistou, K A, Fischer, K, Hofer, E, Schraut, K E, Clark, D W, Nutile, T, Barnes, C L K, Timmers, P R H J, Shen, X, Gandin, I, McDaid, A F, Hansen, T F, Gordon, S D, Giulianini, F, Boutin, T S, Abdellaoui, A, Zhao, W, Medina-Gomez, C, Bartz, T M, Trompet, S, Lange, L A, Raffield, L, van der Spek, A, Galesloot, T E, Proitsi, P, Yanek, L R, Bielak, L F, Payton, A, Murgia, F, Concas, M P, Biino, G, Tajuddin, S M, Seppälä, I, Amin, N, Boerwinkle, E, Børglum, A D, Campbell, A, Demerath, E W, Demuth, I, Faul, J D, Ford, I, Gialluisi, A, Gögele, M, Graff, M, Hingorani, A, Hottenga, J-J, Hougaard, D M, Hurme, M A, Ikram, M A, Jylhä, M, Kuh, D, Ligthart, L, Lill, C M, Lindenberger, U, Lumley, T, Mägi, R, Marques-Vidal, P, Medland, S E, Milani, L, Nagy, R, Ollier, W E R, Peyser, P A, Pramstaller, P P, Ridker, P M, Rivadeneira, F, Ruggiero, D, Saba, Y, Schmidt, R, Schmidt, H, Slagboom, P E, Smith, B H, Smith, J A, Sotoodehnia, N, Steinhagen-Thiessen, E, van Rooij, F J A, Verbeek, A L, Vermeulen, S H, Vollenweider, P, Wang, Y, Werge, T, Whitfield, J B, Zonderman, A B, Lehtimäki, T, Evans, M K, Pirastu, M, Fuchsberger, C, Bertram, L, Pendleton, N, Kardia, S L R, Ciullo, M, Becker, D M, Wong, A, Psaty, B M, van Duijn, C M, Wilson, J G, Jukema, J W, Kiemeney, L, Uitterlinden, A G, Franceschini, N, North, K E, Weir, D R, Metspalu, A, Boomsma, D I, Hayward, C, Chasman, D, Martin, N G, Sattar, N, Campbell, H, Esko, T, Kutalik, Z & Wilson, J F 2017, ' Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity ', Nature Communications, vol. 8, 910 . https://doi.org/10.1038/s41467-017-00934-5
Joshi, P K, Pirastu, N, Kentistou, K A, Fischer, K, Hofer, E, Schraut, K E, Clark, D W, Nutile, T, Barnes, C L K, Timmers, P R H J, Shen, X, Gandin, I, McDaid, A F, Hansen, T F, Gordon, S D, Giulianini, F, Boutin, T S, Abdellaoui, A, Zhao, W, Medina-Gomez, C, Bartz, T M, Trompet, S, Lange, L A, Raffield, L, van der Spek, A, Galesloot, T E, Proitsi, P, Yanek, L R, Bielak, L F, Payton, A, Murgia, F, Concas, M P, Biino, G, Tajuddin, S M, Seppälä, I, Amin, N, Boerwinkle, E, Børglum, A D, Campbell, A, Demerath, E W, Demuth, I, Faul, J D, Ford, I, Gialluisi, A, Gögele, M, Graff, M, Hingorani, A, Hottenga, J-J, Hougaard, D M, Hurme, M A, Ikram, M A, Jylhä, M, Kuh, D, Ligthart, L, Lill, C M, Lindenberger, U, Lumley, T, Mägi, R, Marques-Vidal, P, Medland, S E, Milani, L, Nagy, R, Ollier, W E R, Peyser, P A, Pramstaller, P P, Ridker, P M, Rivadeneira, F, Ruggiero, D, Saba, Y, Schmidt, R, Schmidt, H, Slagboom, P E, Smith, B H, Smith, J A, Sotoodehnia, N, Steinhagen-Thiessen, E, van Rooij, F J A, Verbeek, A L, Vermeulen, S H, Vollenweider, P, Wang, Y, Werge, T, Whitfield, J B, Zonderman, A B, Lehtimäki, T, Evans, M K, Pirastu, M, Fuchsberger, C, Bertram, L, Pendleton, N, Kardia, S L R, Ciullo, M, Becker, D M, Wong, A, Psaty, B M, van Duijn, C M, Wilson, J G, Jukema, J W, Kiemeney, L, Uitterlinden, A G, Franceschini, N, North, K E, Weir, D R, Metspalu, A, Boomsma, D I, Hayward, C, Chasman, D, Martin, N G, Sattar, N, Campbell, H, Esko, T, Kutalik, Z & Wilson, J F 2017, ' Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity ', Nature Communications, vol. 8, no. 1, 910, pp. 910 . https://doi.org/10.1038/s41467-017-00934-5
Nature communications, vol. 8, no. 1, pp. 910
Joshi, P K, Pirastu, N, Kentistou, K A, Fischer, K, Hofer, E, Schraut, K E, Clark, D W, Nutile, T, Barnes, C L K, Timmers, P R H J, Shen, X, Gandin, I, Mcdaid, A F, Hansen, T F, Gordon, S D, Giulianini, F, Boutin, T S, Abdellaoui, A, Zhao, W, Medina-Gomez, C, Bartz, T M, Trompet, S, Lange, L A, Raffield, L, van der Spek, A, Galesloot, T E, Proitsi, P, Yanek, L R, Bielak, L F, Payton, A, Murgia, F, Concas, M P, Biino, G, Tajuddin, S M, Seppälä, I, Amin, N, Boerwinkle, E, Børglum, A D, Campbell, A, Demerath, E W, Demuth, I, Faul, J D, Ford, I, Gialluisi, A, Gögele, M, Graff, M, Hingorani, A, Hottenga, J-J, Hougaard, D M, Hurme, M A, Ikram, M A, Jylhä, M, Kuh, D, Ligthart, L, Lill, C M, Lindenberger, U, Lumley, T, Mägi, R, Marques-Vidal, P, Medland, S E, Milani, L, Nagy, R, Ollier, W E R, Peyser, P A, Pramstaller, P P, Ridker, P M, Rivadeneira, F, Ruggiero, D, Saba, Y, Schmidt, R, Schmidt, H, Slagboom, P E, Smith, B H, Smith, J A, Sotoodehnia, N, Steinhagen-Thiessen, E, van Rooij, F J A, Verbeek, A L, Vermeulen, S H, Vollenweider, P, Wang, Y, Werge, T, Whitfield, J B, Zonderman, A B, Lehtimäki, T, Evans, M K, Pirastu, M, Fuchsberger, C, Bertram, L, Pendleton, N, Kardia, S L R, Ciullo, M, Becker, D M, Wong, A, Psaty, B M, van Duijn, C M, Wilson, J G, Jukema, J W, Kiemeney, L, Uitterlinden, A G, Franceschini, N, North, K E, Weir, D R, Metspalu, A, Boomsma, D I, Hayward, C, Chasman, D, Martin, N G, Sattar, N, Campbell, H, Esko, T, Kutalik, Z & Wilson, J F 2017, ' Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity ', Nature Communications, vol. 8, 910 . https://doi.org/10.1038/s41467-017-00934-5
Genomic analysis of longevity offers the potential to illuminate the biology of human aging. Here, using genome-wide association meta-analysis of 606,059 parents’ survival, we discover two regions associated with longevity (HLA-DQA1/DRB1 and LPA).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::04242f21b1e2ca28d04a512821c4c048
https://pure.eur.nl/en/publications/e611793d-5f03-48be-a3a5-633895a00a20
https://pure.eur.nl/en/publications/e611793d-5f03-48be-a3a5-633895a00a20
Autor:
Megremis, Spyridon, Walker, Thomas D. J., He, Xiaotong, O'Sullivan, James, Ollier, William E. R., Chinoy, Hector, Pendleton, Neil, Payton, Antony, Hampson, Lynne, Hampson, Ian, Lamb, Janine A.
Publikováno v:
Communications Biology; 3/26/2021, Vol. 4 Issue 1, p1-14, 14p
Akademický článek
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