Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Olli Tynninen"'
Autor:
Anne M. Kerola, Kari K. Eklund, Heikki Valleala, Olli Tynninen, Jaakko Helve, Ville Haapamäki, Mari Eriksson
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-9 (2024)
Abstract Background Necrotizing myopathies and muscle necrosis can be caused by immune-mediated mechanisms, drugs, ischemia, and infections, and differential diagnosis may be challenging. Case presentation We describe a case of diabetic myonecrosis c
Externí odkaz:
https://doaj.org/article/a165e49359ac4a50ab3ce97b7f7ef6df
Autor:
Pyry Dillemuth, Tuomas Karskela, Abiodun Ayo, Jesse Ponkamo, Jonne Kunnas, Johan Rajander, Olli Tynninen, Anne Roivainen, Pirjo Laakkonen, Anu J. Airaksinen, Xiang-Guo Li
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-16 (2024)
Abstract Background Fatty acid binding protein 3 (FABP3) is a target with clinical relevance and the peptide ligand ACooP has been identified for FABP3 targeting. ACooP is a linear decapeptide containing a free amino and thiol group, which provides o
Externí odkaz:
https://doaj.org/article/185a523a91304304bb622a98e1a910fc
Autor:
Philipp Sievers, Martin Sill, Daniel Schrimpf, Zied Abdullaev, Andrew M. Donson, Jessica A. Lake, Dennis Friedel, David Scheie, Olli Tynninen, Tuomas Rauramaa, Kaisa L. Vepsäläinen, David Samuel, Rebecca Chapman, Richard G. Grundy, Kristian W. Pajtler, Arnault Tauziède-Espariat, Alice Métais, Pascale Varlet, Matija Snuderl, Thomas S. Jacques, Kenneth Aldape, David E. Reuss, Andrey Korshunov, Wolfgang Wick, Stefan M. Pfister, Andreas von Deimling, Felix Sahm, David T. W. Jones
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-8 (2023)
Abstract Pediatric neoplasms in the central nervous system (CNS) show extensive clinical and molecular heterogeneity and are fundamentally different from those occurring in adults. Molecular genetic testing contributes to accurate diagnosis and enabl
Externí odkaz:
https://doaj.org/article/9f54e4ebe7994704862580e7e4db4d5b
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 16 (2023)
IgG4-related disease (IgG4-RD) is an emerging immune-mediated chronic fibrotic disease characterized by tumour-like mass formation. Reports of brain parenchymal involvement in IgG4-RD are rare and complete treatment-related remission of lesions has n
Externí odkaz:
https://doaj.org/article/1f80d3ec2c2d403a8665451b368d90dc
Autor:
Vadim Le Joncour, Pauliina Filppu, Maija Hyvönen, Minna Holopainen, S Pauliina Turunen, Harri Sihto, Isabel Burghardt, Heikki Joensuu, Olli Tynninen, Juha Jääskeläinen, Michael Weller, Kaisa Lehti, Reijo Käkelä, Pirjo Laakkonen
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 6, Pp 1-21 (2019)
Abstract The current clinical care of glioblastomas leaves behind invasive, radio‐ and chemo‐resistant cells. We recently identified mammary‐derived growth inhibitor (MDGI/FABP3) as a biomarker for invasive gliomas. Here, we demonstrate a novel
Externí odkaz:
https://doaj.org/article/c1eac63859984fbf8aeb614cf57f36f3
Autor:
Jussi‐Pekka Tolonen, Anne Hekkala, Outi Kuismin, Hannu Tuominen, Maria Suo‐Palosaari, Olli Tynninen, Riitta Niinimäki
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 9, Pp n/a-n/a (2020)
Abstract Background Medulloblastomas (MBs) are a heterogeneous group of childhood brain tumors with four consensus subgroups, namely MBSHH, MBWNT, MBGroup 3, and MBGroup 4, representing the second most common type of pediatric brain cancer after high
Externí odkaz:
https://doaj.org/article/602fc037fb054bc1a43bc7a8ccbe1ec3
Autor:
Joham Choque-Velasquez, MD, Julio C. Resendiz-Nieves, MD, PhD, Behnam Rezai Jahromi, MD, Roberto Colasanti, MD, Olli Tynninen, MD, Juhani Collan, MD, Mika Niemelä, MD, PhD, Juha Hernesniemi, MD, PhD
Publikováno v:
Interdisciplinary Neurosurgery, Vol 18, Iss , Pp - (2019)
Background: Pineoblastomas are very rare malignant lesions with a bad prognosis and high mortality during the first five years from diagnosis. Report of cases: We present a retrospective review of three patients with histologically confirmed pineobla
Externí odkaz:
https://doaj.org/article/694cddd4f77b4745967592633fdbbe31
Autor:
Sanna Kaye, A. Inkeri Lokki, Anna Hanttu, Eija Nissilä, Sini Heinonen, Antti Hakkarainen, Jesper Lundbom, Nina Lundbom, Lilli Saarinen, Olli Tynninen, Maheswary Muniandy, Aila Rissanen, Jaakko Kaprio, Seppo Meri, Kirsi H. Pietiläinen
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Inflammation is an important mediator of obesity-related complications such as the metabolic syndrome but its causes and mechanisms are unknown. As the complement system is a key mediator of inflammation, we studied whether it is activated in acquire
Externí odkaz:
https://doaj.org/article/7b917bfa8210493a90c102f2ada75613
Publikováno v:
Prenatal Diagnosis.
We report a case of pyruvate dehydrogenase E1 alpha subunit deficiency associated with a novel hemizygous PDHA1 variant presenting prenatally as multiple structural brain abnormalities in a male fetus. A healthy Finnish couple was initially referred
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fdb27d4666f2a5860571f2d049f6a8
https://doi.org/10.1002/pd.6349
https://doi.org/10.1002/pd.6349
Autor:
Olli‐Pekka Pulkka, Leevi Viisanen, Olli Tynninen, Maria Laaksonen, Peter Reichardt, Annette Reichardt, Mikael Eriksson, Kirsten Sundby Hall, Eva Wardelmann, Bengt Nilsson, Harri Sihto, Heikki Joensuu
Publikováno v:
Journal of Cellular and Molecular Medicine. 26:1083-1094
Gastrointestinal stromal tumour (GIST), the most common sarcoma of the gastrointestinal tract, can be treated effectively with tyrosine kinase inhibitors, such as imatinib. Cancer immune therapy has limited efficacy, and little is known about the imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88e517b2dd57dfed56ef392aaeef940
https://doi.org/10.1111/jcmm.17163
https://doi.org/10.1111/jcmm.17163