Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Olli Matilainen"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Folate receptor (FR) alpha (FOLR1) and beta (FOLR2) are membrane-anchored folate transporters that are expressed at low levels in normal tissues, while their expression is strongly increased in several cancers. Intriguingly, although the fun
Externí odkaz:
https://doaj.org/article/774ff804ca7a40fdb89c4e4c3f86200f
Autor:
Olli Matilainen, Maroun S. Bou Sleiman, Pedro M. Quiros, Susana M. D. A. Garcia, Johan Auwerx
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Changes in chromatin structure have been linked to organismal ageing. Here the authors show that altered histone expression and mitochondrial stress during C. elegans development result in chromatin changes and a cytosolic stress response that affect
Externí odkaz:
https://doaj.org/article/f2448e82fe1a47ca8ebd24b4a5a05de3
Publikováno v:
Cell Reports, Vol 3, Iss 6, Pp 1980-1995 (2013)
The proteasome plays an important role in proteostasis by carrying out controlled protein degradation in the cell. Impairments in proteasome function are associated with severe and often age-related diseases. Here, we have characterized a molecular m
Externí odkaz:
https://doaj.org/article/82a49a2664564224a07eef53499c5525
Autor:
Isabel Weinheimer, Yaming Jiu, Minna-Liisa Rajamäki, Olli Matilainen, Jukka Kallijärvi, Wilmer J Cuellar, Rui Lu, Mart Saarma, Carina I Holmberg, Jussi Jäntti, Jari P T Valkonen
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004711 (2015)
Certain RNA and DNA viruses that infect plants, insects, fish or poikilothermic animals encode Class 1 RNaseIII endoribonuclease-like proteins. dsRNA-specific endoribonuclease activity of the RNaseIII of rock bream iridovirus infecting fish and Sweet
Externí odkaz:
https://doaj.org/article/22bd2cc0396141ed8f0645e2eaa6445d
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59096 (2013)
UV damage activates cellular stress signaling pathways, causes DNA helix distortions and inhibits transcription by RNA polymerases I and II. In particular, the nucleolus, which is the site of RNA polymerase I transcription and ribosome biogenesis, di
Externí odkaz:
https://doaj.org/article/ba622ce2bbbd45019cbfbb7f046e7c58
Autor:
Xuan Li, Olli Matilainen, Congyu Jin, Kira M Glover-Cutter, Carina I Holmberg, T Keith Blackwell
Publikováno v:
PLoS Genetics, Vol 7, Iss 6, p e1002119 (2011)
SKN-1, the Caenorhabditis elegans Nrf1/2/3 ortholog, promotes both oxidative stress resistance and longevity. SKN-1 responds to oxidative stress by upregulating genes that detoxify and defend against free radicals and other reactive molecules, a SKN-
Externí odkaz:
https://doaj.org/article/996c149acbfe4d2f86e1d6aaf8102556
Publikováno v:
Cell Stress & Chaperones
Variation in ambient growth temperature can cause changes in normal animal physiology and cellular functions such as control of protein homeostasis. A key mechanism for maintaining proteostasis is the selective degradation of polyubiquitinated protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94844ba64b3b5a6ffc55174eb6eef583
https://doi.org/10.1007/s12192-020-01107-y
https://doi.org/10.1007/s12192-020-01107-y
Autor:
Ana R. S. Ribeiro, Ruslan I. Sadreyev, Olli Matilainen, Murat Cetinbas, Jens Verbeeren, Heini Sood, Susana M. D. A. Garcia
Publikováno v:
Genetics
Muscleblind-like splicing regulators (MBNLs) are RNA-binding factors that have an important role in developmental processes. Dysfunction of these factors is a key contributor of different neuromuscular degenerative disorders, including Myotonic Dystr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956bffbb2dd33a6e468c1925251b9336
https://doi.org/10.1093/genetics/iyab114
https://doi.org/10.1093/genetics/iyab114
Autor:
Anna Mellul, Haya Chahine, Maya Braun, Lena Qawasmi, Danielle Share, Ehud Cohen, Irene Guberman, Noa Roitenberg, Yuval Tabach, Olli Matilainen, Susana M. D. A. Garcia, Doron Stupp, Emiliano Cohen, Lamis Naddaf
Publikováno v:
Journal of Molecular Biology. 431:1711-1728
Myotonic dystrophy type 1 is an autosomal-dominant inherited disorder caused by the expansion of CTG repeats in the 3' untranslated region of the DMPK gene. The RNAs bearing these expanded repeats have a range of toxic effects. Here we provide eviden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2cc5dd991dc9c459b3066dabd7235e3
https://doi.org/10.1016/j.jmb.2019.03.003
https://doi.org/10.1016/j.jmb.2019.03.003
Autor:
Jens Verbeeren, Ruslan I. Sadreyev, Murat Cetinbas, Susana M. D. A. Garcia, Ana R. S. Ribeiro, Olli Matilainen
Muscleblind-like splicing regulators (MBNLs) are alternative splicing factors that have an important role in developmental processes. Dysfunction of these factors is a key contributor of different neuromuscular degenerative disorders, including Myoto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc715891f3eacbce663f298a5365643e
https://doi.org/10.1101/2021.02.22.432374
https://doi.org/10.1101/2021.02.22.432374
