Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Olli‐Pekka Pulkka"'
Autor:
Timo‐Pekka K. Lehto, Ruusu‐Maaria Kovanen, Susanna Lintula, Adrian Malén, Carolin Stürenberg, Andrew Erickson, Olli‐Pekka Pulkka, Ulf‐Håkan Stenman, Eleftherios P. Diamandis, Antti Rannikko, Tuomas Mirtti, Hannu Koistinen
Publikováno v:
International Journal of Cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae9352a73f305d6a16d3d4babdcf6039
https://doi.org/10.1002/ijc.34551
https://doi.org/10.1002/ijc.34551
Autor:
Olli‐Pekka Pulkka, Leevi Viisanen, Olli Tynninen, Maria Laaksonen, Peter Reichardt, Annette Reichardt, Mikael Eriksson, Kirsten Sundby Hall, Eva Wardelmann, Bengt Nilsson, Harri Sihto, Heikki Joensuu
Publikováno v:
Journal of Cellular and Molecular Medicine. 26:1083-1094
Gastrointestinal stromal tumour (GIST), the most common sarcoma of the gastrointestinal tract, can be treated effectively with tyrosine kinase inhibitors, such as imatinib. Cancer immune therapy has limited efficacy, and little is known about the imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88e517b2dd57dfed56ef392aaeef940
https://doi.org/10.1111/jcmm.17163
https://doi.org/10.1111/jcmm.17163
Autor:
Heikki Joensuu, Harri Sihto, Patrick Schöffski, Olli Kallioniemi, Sampsa Hautaniemi, Rainer Lehtonen, Pirjo Laakkonen, Markku Varjosalo, Krister Wennerberg, Maria Laaksonen, Evgeny Kulesskiy, Astrid Murumägi, Salla Keskitalo, Alejandra Cervera, Katherine Icay, Olli Tynninen, John-Patrick Mpindi, Agnieszka Wozniak, Yemarshet K. Gebreyohannes, Olli-Pekka Pulkka
Supplementary Table S3. Comprehensive drug sensitivity and resistance testing with 200 cancer drugs. Cell viability in GIST882 and GIST48 cell lines was measured in five different concentrations over a 10,000-fold concentration range.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::480c94a591329a9844cbe316d4145e36
https://doi.org/10.1158/1078-0432.22471833.v1
https://doi.org/10.1158/1078-0432.22471833.v1
Autor:
Heikki Joensuu, Harri Sihto, Patrick Schöffski, Olli Kallioniemi, Sampsa Hautaniemi, Rainer Lehtonen, Pirjo Laakkonen, Markku Varjosalo, Krister Wennerberg, Maria Laaksonen, Evgeny Kulesskiy, Astrid Murumägi, Salla Keskitalo, Alejandra Cervera, Katherine Icay, Olli Tynninen, John-Patrick Mpindi, Agnieszka Wozniak, Yemarshet K. Gebreyohannes, Olli-Pekka Pulkka
Supplementary Figure S1. A box-whisker plot showing the relative KIT, ANO1, and PRKCQ (encodes for protein kinase C theta) mRNA expression in soft-tissue sarcoma samples in the MediSapiens database. Supplementary Figure S2. PDE3A (A) and KIT (B) expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af156eed6057303f5b983ab6ae6318ae
https://doi.org/10.1158/1078-0432.22471845.v1
https://doi.org/10.1158/1078-0432.22471845.v1
Autor:
Heikki Joensuu, Harri Sihto, Patrick Schöffski, Olli Kallioniemi, Sampsa Hautaniemi, Rainer Lehtonen, Pirjo Laakkonen, Markku Varjosalo, Krister Wennerberg, Maria Laaksonen, Evgeny Kulesskiy, Astrid Murumägi, Salla Keskitalo, Alejandra Cervera, Katherine Icay, Olli Tynninen, John-Patrick Mpindi, Agnieszka Wozniak, Yemarshet K. Gebreyohannes, Olli-Pekka Pulkka
Supplementary Table S5. List of genes most affected by anagrelide treatment and protein expression data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bff0fc0cf1d21420e91520f1aec8f03
https://doi.org/10.1158/1078-0432.22471827
https://doi.org/10.1158/1078-0432.22471827
Autor:
Heikki Joensuu, Harri Sihto, Patrick Schöffski, Olli Kallioniemi, Sampsa Hautaniemi, Rainer Lehtonen, Pirjo Laakkonen, Markku Varjosalo, Krister Wennerberg, Maria Laaksonen, Evgeny Kulesskiy, Astrid Murumägi, Salla Keskitalo, Alejandra Cervera, Katherine Icay, Olli Tynninen, John-Patrick Mpindi, Agnieszka Wozniak, Yemarshet K. Gebreyohannes, Olli-Pekka Pulkka
Supplemental legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa3d7b779e5c7b2c0ec12160dff88aa
https://doi.org/10.1158/1078-0432.22471848
https://doi.org/10.1158/1078-0432.22471848
Autor:
Heikki Joensuu, Harri Sihto, Patrick Schöffski, Olli Kallioniemi, Sampsa Hautaniemi, Rainer Lehtonen, Pirjo Laakkonen, Markku Varjosalo, Krister Wennerberg, Maria Laaksonen, Evgeny Kulesskiy, Astrid Murumägi, Salla Keskitalo, Alejandra Cervera, Katherine Icay, Olli Tynninen, John-Patrick Mpindi, Agnieszka Wozniak, Yemarshet K. Gebreyohannes, Olli-Pekka Pulkka
Supplementary Table S4. miRNA expression, mRNA expression, and associated pathways perturbed in the GIST882 cell line after anagrelide treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d956d49624c63df941a7fe419fb3361
https://doi.org/10.1158/1078-0432.22471830.v1
https://doi.org/10.1158/1078-0432.22471830.v1
Autor:
Heikki Joensuu, Harri Sihto, Patrick Schöffski, Olli Kallioniemi, Sampsa Hautaniemi, Rainer Lehtonen, Pirjo Laakkonen, Markku Varjosalo, Krister Wennerberg, Maria Laaksonen, Evgeny Kulesskiy, Astrid Murumägi, Salla Keskitalo, Alejandra Cervera, Katherine Icay, Olli Tynninen, John-Patrick Mpindi, Agnieszka Wozniak, Yemarshet K. Gebreyohannes, Olli-Pekka Pulkka
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd977504a190aca5aa4ffbfba234ba0
https://doi.org/10.1158/1078-0432.22471842
https://doi.org/10.1158/1078-0432.22471842
Autor:
Heikki Joensuu, Harri Sihto, Patrick Schöffski, Olli Kallioniemi, Sampsa Hautaniemi, Rainer Lehtonen, Pirjo Laakkonen, Markku Varjosalo, Krister Wennerberg, Maria Laaksonen, Evgeny Kulesskiy, Astrid Murumägi, Salla Keskitalo, Alejandra Cervera, Katherine Icay, Olli Tynninen, John-Patrick Mpindi, Agnieszka Wozniak, Yemarshet K. Gebreyohannes, Olli-Pekka Pulkka
Supplementary Table S6. The primers used in the quantitative PCR analyses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a65d030283ba217432eb105221e8078
https://doi.org/10.1158/1078-0432.22471824
https://doi.org/10.1158/1078-0432.22471824
Autor:
Heikki Joensuu, Harri Sihto, Patrick Schöffski, Olli Kallioniemi, Sampsa Hautaniemi, Rainer Lehtonen, Pirjo Laakkonen, Markku Varjosalo, Krister Wennerberg, Maria Laaksonen, Evgeny Kulesskiy, Astrid Murumägi, Salla Keskitalo, Alejandra Cervera, Katherine Icay, Olli Tynninen, John-Patrick Mpindi, Agnieszka Wozniak, Yemarshet K. Gebreyohannes, Olli-Pekka Pulkka
Supplementary Table S1. The outlier mRNA expression profiles of the gene tissue index (GTI) outlier analysis. The list of 2415 outlier genes in GIST is ranked by the gene tissue index.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::667e500e8b895899f96aea076661dd7f
https://doi.org/10.1158/1078-0432.22471839.v1
https://doi.org/10.1158/1078-0432.22471839.v1