Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Olley, Gabrielle"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Olley, Gabrielle Jade
Acetylation of lysine residues is a histone modification associated with active chromatin. The modified residues provide docking sites for the epigenetic reader BRD4, which binds to the acetylated lysines via its two bromodomains. BRD4 is known to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______463::1a2abbce6adfebcd65fcc5ad98c6aae5
http://hdl.handle.net/1842/35802
http://hdl.handle.net/1842/35802
Autor:
Olley, Gabrielle, Ansari, Morad, Bengani, Hemant, Grimes, Graeme R., Rhodes, James, von Kriegsheim, Alex, Blatnik, Ana, Stewart, Fiona J., Wakeling, Emma, Carroll, Nicola, Ross, Alison, Park, Soo-Mi, Deciphering Developmental Disorders Study, Bickmore, Wendy A., Pradeepa, Madapura M., FitzPatrick, David R.
We found that the clinical phenotype associated with BRD4 haploinsufficiency overlapped with that of Cornelia de Lange syndrome (CdLS), which is most often caused by mutation of NIPBL. More typical CdLS was observed with a de novo BRD4 missense varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::2f9d3727ead1d85360dfbaa49071bf94
https://eprints.gla.ac.uk/169404/1/169404.pdf
https://eprints.gla.ac.uk/169404/1/169404.pdf
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Olley, Gabrielle, Ansari, Morad, Bengani, Hemant, Grimes, Graeme, Rhodes, James, von Kriegsheim, Alex, Blatnik, Ana, Stewart, Fiona, Wakeling, Emma, Carroll, Nicola, Ross, Alison, Park, Soo-Mi, Bickmore, Wendy, Pradeepa, Madapura, FitzPatrick, David
Publikováno v:
Nature Genetics; March 2018, Vol. 50 Issue: 3 p329-332, 4p
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Olley, Gabrielle, Ansari, Morad, Bengani, Hemant, Grimes, Graeme, Rhodes, James, Kriegsheim, Alex, Blatnik, Ana, Stewart, Fiona, Wakeling, Emma, Carroll, Nicola, Ross, Alison, Park, Soo-Mi, Bickmore, Wendy, Pradeepa, Madapura, FitzPatrick, David
Publikováno v:
Nature Genetics; July 2019, Vol. 51 Issue: 7 p1192-1192, 1p
Autor:
Olley, Gabrielle, Ansari, Morad, Bengani, Hemant, Grimes, Graeme, Rhodes, James, von Kriegsheim, Alex, Blatnik, Ana, Stewart, Fiona, Wakeling, Emma, Carroll, Nicola, Ross, Alison, Park, Soo-Mi, Bickmore, Wendy, Pradeepa, Madapura, FitzPatrick, David
Publikováno v:
Nature Genetics; May 2018, Vol. 50 Issue: 5 p767-767, 1p
Autor:
Olley G; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK., Ansari M; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK., Bengani H; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK., Grimes GR; MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK., Rhodes J; Department of Biochemistry, Oxford University, Oxford, UK., von Kriegsheim A; MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK., Blatnik A; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK.; Cancer Genetics Clinic, Institute of Oncology, Ljubljana, Slovenia., Stewart FJ; Department of Medical Genetics, Belfast City Hospital, Belfast, UK., Wakeling E; North West Thames Regional Genetics Service, London North West Healthcare NHS Trust, Harrow, UK., Carroll N; South East Scotland Regional Genetics Services, Western General Hospital, Edinburgh, UK., Ross A; Department of Medical Genetics, Ashgrove House, Foresterhill, Aberdeen, UK., Park SM; East Anglian Medical Genetics Service, Clinical Genetics, Addenbrooke's Treatment Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Bickmore WA; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK. wendy.bickmore@igmm.ed.ac.uk., Pradeepa MM; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK. pmadap@essex.ac.uk.; School of Biological Sciences, University of Essex, Colchester, UK. pmadap@essex.ac.uk., FitzPatrick DR; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK. david.fitzpatrick@ed.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2018 May; Vol. 50 (5), pp. 767.
Autor:
Olley G; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK., Ansari M; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK., Bengani H; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK., Grimes GR; MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK., Rhodes J; Department of Biochemistry, Oxford University, Oxford, UK., von Kriegsheim A; MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK., Blatnik A; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK.; Cancer Genetics Clinic, Institute of Oncology, Ljubljana, Slovenia., Stewart FJ; Department of Medical Genetics, Belfast City Hospital, Belfast, UK., Wakeling E; North West Thames Regional Genetics Service, London North West Healthcare NHS Trust, Harrow, UK., Carroll N; South East Scotland Regional Genetics Services, Western General Hospital, Edinburgh, UK., Ross A; Department of Medical Genetics, Ashgrove House, Foresterhill, Aberdeen, UK., Park SM; East Anglian Medical Genetics Service, Clinical Genetics, Addenbrooke's Treatment Centre, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Bickmore WA; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK. wendy.bickmore@igmm.ed.ac.uk., Pradeepa MM; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK. pmadap@essex.ac.uk.; School of Biological Sciences, University of Essex, Colchester, UK. pmadap@essex.ac.uk., FitzPatrick DR; MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK. david.fitzpatrick@ed.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2018 Mar; Vol. 50 (3), pp. 329-332. Date of Electronic Publication: 2018 Jan 29.