Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Olle, Sangfelt"'
Autor:
Alena Malyukova, Mari Lahnalampi, Ton Falqués-Costa, Petri Pölönen, Mikko Sipola, Juha Mehtonen, Susanna Teppo, Karen Akopyan, Johanna Viiliainen, Olli Lohi, Anna K. Hagström-Andersson, Merja Heinäniemi, Olle Sangfelt
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-38 (2024)
Abstract Background Targeted therapies exploiting vulnerabilities of cancer cells hold promise for improving patient outcome and reducing side-effects of chemotherapy. However, efficacy of precision therapies is limited in part because of tumor cell
Externí odkaz:
https://doaj.org/article/89499d14af9b44a5bde5f230fc540a77
Autor:
Linda Vidarsdottir, Alireza Azimi, Ishani Das, Ingibjorg Sigvaldadottir, Aldwin Suryo Rahmanto, Andreas Petri, Sakari Kauppinen, Christian Ingvar, Göran Jönsson, Håkan Olsson, Marianne Frostvik Stolt, Rainer Tuominen, Olle Sangfelt, Katja Pokrovskaja Tamm, Johan Hansson, Dan Grandér, Suzanne Egyházi Brage, Per Johnsson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract BRAF inhibitors (BRAFi) selectively target oncogenic BRAFV600E/K and are effective in 80% of advanced cutaneous malignant melanoma cases carrying the V600 mutation. However, the development of drug resistance limits their clinical efficacy.
Externí odkaz:
https://doaj.org/article/f88ae22862f24b9684552bdca23e8edf
Autor:
Thibaud J. C. Richard, Laura K. Herzog, Julia Vornberger, Aldwin Suryo Rahmanto, Olle Sangfelt, Florian A. Salomons, Nico P. Dantuma
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Even though K63-linked polyubiquitin chains do not target proteins for proteasomal degradation, they play nevertheless a complementary protective role in maintaining protein homeostasis by directing malfunctioning proteins and organelles to
Externí odkaz:
https://doaj.org/article/c16e088089de40dbade83e4e69e958b1
Autor:
Juha Mehtonen, Susanna Teppo, Mari Lahnalampi, Aleksi Kokko, Riina Kaukonen, Laura Oksa, Maria Bouvy-Liivrand, Alena Malyukova, Artturi Mäkinen, Saara Laukkanen, Petri I. Mäkinen, Samuli Rounioja, Pekka Ruusuvuori, Olle Sangfelt, Riikka Lund, Tapio Lönnberg, Olli Lohi, Merja Heinäniemi
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-25 (2020)
Abstract Background Tight regulatory loops orchestrate commitment to B cell fate within bone marrow. Genetic lesions in this gene regulatory network underlie the emergence of the most common childhood cancer, acute lymphoblastic leukemia (ALL). The i
Externí odkaz:
https://doaj.org/article/24be6debd5e54c1482d9d4574cdcc67a
Autor:
Rami Mäkelä, Antti Arjonen, Aldwin Suryo Rahmanto, Ville Härmä, Janne Lehtiö, Teijo Kuopio, Thomas Helleday, Olle Sangfelt, Juha Kononen, Juha K. Rantala
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 9, Pp 390-398 (2020)
Epithelial–myoepithelial carcinoma (EMC) is a rare subtype of salivary gland neoplasms. Since the initial description of the cancer, just over 300 cases have been reported. EMCs occupy a biphasic cellular differentiation-state defined by the consti
Externí odkaz:
https://doaj.org/article/b2d81484fc1741c8bc0de9e647a7ca62
Autor:
Andrä Brunner, Aldwin Suryo Rahmanto, Henrik Johansson, Marcela Franco, Johanna Viiliäinen, Mohiuddin Gazi, Oliver Frings, Erik Fredlund, Charles Spruck, Janne Lehtiö, Juha K Rantala, Lars-Gunnar Larsson, Olle Sangfelt
Publikováno v:
eLife, Vol 9 (2020)
Inhibition of WEE1 kinase by AZD1775 has shown promising results in clinical cancer trials, but markers predicting AZD1775 response are lacking. Here we analysed AZD1775 response in a panel of human breast cancer (BC) cell lines by global proteome/tr
Externí odkaz:
https://doaj.org/article/c498116f3f834b90a997e94962d531e9
Autor:
Fredrik J. Swartling, Holger Weishaupt, Robert J. Wechsler-Reya, Ulrich Schüller, Steven C. Clifford, Olle Sangfelt, Michael D. Taylor, Xingqi Chen, Géraldine Giraud, Helena Jernberg-Wiklund, Matko Čančer, Marc Remke, Antonia Kalushkova, Adrian M. Dubuc, Rebecca M. Hill, Grammatiki Fotaki, Stacey Richardson, Amelie S. Wenz, Yonglong Dang, Mar Ballester Bravo, Anders Sundström, Jessica M. Rusert, Annemieke D. Verbaan, Damiana Sattanino, Oliver J. Mainwaring, Thale Kristin Olsen, Tobias Bergström, Aldwin Suryo Rahmanto, Alexandra Garancher, Sonja Hutter, Gabriela Rosén, Vasil Savov, Miao Zhao, Sara Bolin, Karl O. Holmberg, Anna Borgenvik
Resource Table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f9e62c1e38cb49885bbd558c5c889e
https://doi.org/10.1158/0008-5472.22433306
https://doi.org/10.1158/0008-5472.22433306
Autor:
Fredrik J. Swartling, Holger Weishaupt, Robert J. Wechsler-Reya, Ulrich Schüller, Steven C. Clifford, Olle Sangfelt, Michael D. Taylor, Xingqi Chen, Géraldine Giraud, Helena Jernberg-Wiklund, Matko Čančer, Marc Remke, Antonia Kalushkova, Adrian M. Dubuc, Rebecca M. Hill, Grammatiki Fotaki, Stacey Richardson, Amelie S. Wenz, Yonglong Dang, Mar Ballester Bravo, Anders Sundström, Jessica M. Rusert, Annemieke D. Verbaan, Damiana Sattanino, Oliver J. Mainwaring, Thale Kristin Olsen, Tobias Bergström, Aldwin Suryo Rahmanto, Alexandra Garancher, Sonja Hutter, Gabriela Rosén, Vasil Savov, Miao Zhao, Sara Bolin, Karl O. Holmberg, Anna Borgenvik
Supplementary figure 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1912492597cfade9206b22e304f40fbd
https://doi.org/10.1158/0008-5472.22433336
https://doi.org/10.1158/0008-5472.22433336
Autor:
Fredrik J. Swartling, Holger Weishaupt, Robert J. Wechsler-Reya, Ulrich Schüller, Steven C. Clifford, Olle Sangfelt, Michael D. Taylor, Xingqi Chen, Géraldine Giraud, Helena Jernberg-Wiklund, Matko Čančer, Marc Remke, Antonia Kalushkova, Adrian M. Dubuc, Rebecca M. Hill, Grammatiki Fotaki, Stacey Richardson, Amelie S. Wenz, Yonglong Dang, Mar Ballester Bravo, Anders Sundström, Jessica M. Rusert, Annemieke D. Verbaan, Damiana Sattanino, Oliver J. Mainwaring, Thale Kristin Olsen, Tobias Bergström, Aldwin Suryo Rahmanto, Alexandra Garancher, Sonja Hutter, Gabriela Rosén, Vasil Savov, Miao Zhao, Sara Bolin, Karl O. Holmberg, Anna Borgenvik
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22efa60c78744a2d1ee1b74fa2e6c10b
https://doi.org/10.1158/0008-5472.22433321.v1
https://doi.org/10.1158/0008-5472.22433321.v1
Autor:
Fredrik J. Swartling, Holger Weishaupt, Robert J. Wechsler-Reya, Ulrich Schüller, Steven C. Clifford, Olle Sangfelt, Michael D. Taylor, Xingqi Chen, Géraldine Giraud, Helena Jernberg-Wiklund, Matko Čančer, Marc Remke, Antonia Kalushkova, Adrian M. Dubuc, Rebecca M. Hill, Grammatiki Fotaki, Stacey Richardson, Amelie S. Wenz, Yonglong Dang, Mar Ballester Bravo, Anders Sundström, Jessica M. Rusert, Annemieke D. Verbaan, Damiana Sattanino, Oliver J. Mainwaring, Thale Kristin Olsen, Tobias Bergström, Aldwin Suryo Rahmanto, Alexandra Garancher, Sonja Hutter, Gabriela Rosén, Vasil Savov, Miao Zhao, Sara Bolin, Karl O. Holmberg, Anna Borgenvik
Relapse is the leading cause of death in patients with medulloblastoma, the most common malignant pediatric brain tumor. A better understanding of the mechanisms underlying recurrence could lead to more effective therapies for targeting tumor relapse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b77886ca8f27c3b99dc19b07dfadb1
https://doi.org/10.1158/0008-5472.c.6514337.v1
https://doi.org/10.1158/0008-5472.c.6514337.v1