Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Olivier Toutirais"'
Tissue-plasminogen activator effects on the phenotype of splenic myeloid cells in acute inflammation
Autor:
Célia Seillier, Léonie Lesec, Pauline Hélie, Charlotte Marie, Denis Vivien, Fabian Docagne, Brigitte Le Mauff, Olivier Toutirais
Publikováno v:
Journal of Inflammation, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Tissue-plasminogen activator (tPA) is a serine protease well known for its fibrinolytic function. Recent studies indicate that tPA could also modulate inflammation via plasmin generation and/or by receptor mediated signalling in vitro. Howev
Externí odkaz:
https://doaj.org/article/112f53425753441187043f14f6d731cd
Autor:
Pauline Hélie, Celia Camacho-Toledano, Léonie Lesec, Célia Seillier, Antonio J. Miralles, Maria Cristina Ortega, Sylvaine Guérit, Héloïse Lebas, Isabelle Bardou, Virginia Vila-del Sol, Denis Vivien, Brigitte Le Mauff, Diego Clemente, Fabian Docagne, Olivier Toutirais
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-17 (2021)
Abstract Background Tissue plasminogen activator (tPA) is a serine protease involved in fibrinolysis. It is released by endothelial cells, but also expressed by neurons and glial cells in the central nervous system (CNS). Interestingly, this enzyme a
Externí odkaz:
https://doaj.org/article/1d3203b23fab4d6ba6cda1c955e10cd7
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10336 (2022)
The excitatory neurotransmission of the central nervous system (CNS) mainly involves glutamate and its receptors, especially N-methyl-D-Aspartate receptors (NMDARs). These receptors have been extensively described on neurons and, more recently, also
Externí odkaz:
https://doaj.org/article/969a90d07b6846c19d28e6b0181ed38b
Autor:
Kathy Khoy, Delphine Mariotte, Gilles Defer, Gautier Petit, Olivier Toutirais, Brigitte Le Mauff
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Multiple sclerosis is a chronic demyelinating disease of the central nervous system (CNS) with an autoimmune component. Among the recent disease-modifying treatments available, Natalizumab, a monoclonal antibody directed against the alpha chain of th
Externí odkaz:
https://doaj.org/article/c0aac8f89e9a4cc3ab493d319c2acd41
Autor:
Alexandre Couture, Anthony Garnier, Fabian Docagne, Olivier Boyer, Denis Vivien, Brigitte Le-Mauff, Jean-Baptiste Latouche, Olivier Toutirais
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
CD4+ T cells differentiate into various T helper subsets characterized by distinct cytokine secreting profiles that confer them effector functions adapted to a variety of infectious or endogenous threats. Regulatory CD4+ T cells are another specializ
Externí odkaz:
https://doaj.org/article/4a1c67bc23984cca9d680fc6d4f65167
Autor:
Laurent Gilardin, Sandrine Delignat, Ivan Peyron, Mathieu Ing, Yu-Chun Lone, Bagirath Gangadharan, Baptiste Michard, Yousra Kherabi, Meenu Sharma, Anastas Pashov, Jean-Baptiste Latouche, Mohamad Hamieh, Olivier Toutirais, Pascale Loiseau, Lionel Galicier, Agnès Veyradier, Srini Kaveri, Bernard Maillère, Paul Coppo, Sébastien Lacroix-Desmazes
Publikováno v:
Haematologica, Vol 102, Iss 11 (2017)
Acquired thrombotic thrombocytopenic purpura is a rare and severe disease characterized by auto-antibodies directed against “A Disintegrin And Metalloproteinase with Thrombospondin type 1 repeats, 13th member" (ADAMTS13), a plasma protein involved
Externí odkaz:
https://doaj.org/article/80814320e5c548d78a1e434443f0aa11
Autor:
Ludovic Donaghy, Florian Cabillic, Anne Corlu, Octavie Rostan, Olivier Toutirais, Christiane Guguen-Guillouzo, Claude Guiguen, Jean-Pierre Gangneux
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 6, p e703 (2010)
BACKGROUND: Recent advances demonstrated that liver dendritic cells (DCs) promote immunologic hyporesponsiveness that may contribute to hepatic tolerance. Although there has been significant work on the phenotypic and functional roles of such DCs, th
Externí odkaz:
https://doaj.org/article/d6073ba4af774d28b05ed80e97b5bc87
Autor:
Léonie Lesec, Olivier Etard, Richard Macrez, Eric Maubert, Brigitte Le-Mauff, Jérôme Leprince, Véronique Agin, Fabian Docagne, Isabelle Wagnon, Pauline Hélie, Barbara Delaunay, Olivier Toutirais, Denis Vivien, Isabelle Bardou, Mikaël Naveau, Caroline Regnauld
Publikováno v:
Brain. 143:2957-2972
Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is a neuropsychiatric disease characterized by an antibody-mediated autoimmune response against NMDAR. Recent studies have shown that anti-NMDAR antibodies are involved in the pathophysiology of
Publikováno v:
Bull.Cancer
Bull.Cancer, 2020, 107 (7-8), pp.813-822. ⟨10.1016/j.bulcan.2020.04.009⟩
Bull.Cancer, 2020, 107 (7-8), pp.813-822. ⟨10.1016/j.bulcan.2020.04.009⟩
International audience; La lymphopénie radio-induite est fréquente et peut être profonde et durable. Bien que les lymphocytes soient connus depuis longtemps comme des cellules très radiosensibles, la lymphopénie radique est mal caractérisée. L
Autor:
Fabian Docagne, Pauline Hélie, Olivier Toutirais, Célia Seillier, Brigitte Le Mauff, Gautier Petit, Denis Vivien, Diego Clemente
Publikováno v:
Cellular Immunology
The COVID-19 pandemic has once again brought to the forefront the existence of a tight link between the coagulation/fibrinolytic system and the immunologic processes. Tissue-type plasminogen activator (tPA) is a serine protease with a key role in fib