Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Olivier T, Giger"'
Autor:
Ruth T. Casey, Rogier ten Hoopen, Eguzkine Ochoa, Benjamin G. Challis, James Whitworth, Philip S. Smith, Jose Ezequiel Martin, Graeme R. Clark, Fay Rodger, Mel Maranian, Kieren Allinson, Basetti Madhu, Thomas Roberts, Luis Campos, Joanne Anstee, Soo-Mi Park, Alison Marker, Colin Watts, Venkata R. Bulusu, Olivier T. Giger, Eamonn R. Maher
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract The enzyme succinate dehydrogenase (SDH) functions in the citric acid cycle and loss of function predisposes to the development of phaeochromocytoma/paraganglioma (PPGL), wild type gastrointestinal stromal tumour (wtGIST) and renal cell carc
Externí odkaz:
https://doaj.org/article/e8bf863475e349e4b6af0bc8e9781f47
Autor:
Olivier T, Giger, Rogier, Ten Hoopen, David, Shorthouse, Shukri, Abdullahi, Venkata Ramesh, Bulusu, Saili, Jadhav, Eamonn R, Maher, Ruth T, Casey
Publikováno v:
Journal of clinical pathology.
Wild-type gastrointestinal stromal tumours (wtGIST) are frequently caused by inherited pathogenic variants, or somatic alterations in the succinate dehydrogenase subunit genes (MGMT methylation analysis was performed on 65 tumour samples including 47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::58fc52063a18d35b711423d98c5cdc91
https://pubmed.ncbi.nlm.nih.gov/36198483
https://pubmed.ncbi.nlm.nih.gov/36198483
Autor:
Olivier T Giger, Rogier ten Hoopen, David Shorthouse, Shukri Abdullahi, Venkata Ramesh Bulusu, Saili Jadhav, Eamonn R Maher, Ruth T Casey
Publikováno v:
Journal of Clinical Pathology. :jcp-2022
AimsWild-type gastrointestinal stromal tumours (wtGIST) are frequently caused by inherited pathogenic variants, or somatic alterations in the succinate dehydrogenase subunit genes (SDHx). Succinate dehydrogenase is a key enzyme in the citric acid cyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8340ecaad9aa42f8c6db06b6548d40a2
https://doi.org/10.1136/jcp-2022-208462
https://doi.org/10.1136/jcp-2022-208462
Autor:
J Dinesh Kumar, Chris Holmberg, Sandhir Kandola, Islay Steele, Peter Hegyi, Laszlo Tiszlavicz, Rosalind Jenkins, Robert J Beynon, David Peeney, Olivier T Giger, Ahlam Alqahtani, Timothy C Wang, Trevor T Charvat, Mark Penfold, Graham J Dockray, Andrea Varro
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e104877 (2014)
Stromal cells such as myofibroblasts influence tumor progression. The mechanisms are unclear but may involve effects on both tumor cells and recruitment of bone marrow-derived mesenchymal stromal cells (MSCs) which then colonize tumors. Using iTRAQ a
Externí odkaz:
https://doaj.org/article/24567e689f204c02a9c96f54d8dd5d86
Autor:
Hanna Najgebauer, Olivier T. Giger, Andrea Varro, Puthen V. Jithesh, Triantafillos Liloglou, Christopher M. Sanderson
Publikováno v:
Carcinogenesis
There is increasing evidence that stromal myofibroblasts play a key role in the tumour development however, the mechanisms by which they become reprogrammed to assist in cancer progression remain unclear. As cultured cancer-associated myofibroblasts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97b28b15a4507144c7f70a8775e359dc
http://livrepository.liverpool.ac.uk/3031463/1/Carcinogenesis.pdf
http://livrepository.liverpool.ac.uk/3031463/1/Carcinogenesis.pdf
Autor:
J. Dinesh Kumar, Olivier T. Giger, Graham J. Dockray, Marianne Shawe-Taylor, Akos Varga, Andrea Varro, Steven Dodd, Whitney Holden
Publikováno v:
PEPTIDES
Glucagon-like peptide (GLP)-2 stimulates intestinal epithelial proliferation by acting, in part, via IGF release from sub-epithelial myofibroblasts. The response of myofibroblasts to GLP-2 remains incompletely understood. We studied the action of GLP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5732c39279ee7d3280c3ffdaefa7dd30
http://livrepository.liverpool.ac.uk/3022517/1/PEPTIDES-D-16-00588R1~02~20~17.pdf
http://livrepository.liverpool.ac.uk/3022517/1/PEPTIDES-D-16-00588R1~02~20~17.pdf
Autor:
Alix C. O'Meara, Zsuzsanna Varga, Rosmarie Caduff, Alexander Knuth, Olivier T. Giger, Holger Moch, Pierre-André Diener, Dirk Jäger
Publikováno v:
Pathology International. 60:726-734
While mammary Paget's disease (MPD) is clearly linked to breast cancer, the histogenesis of extramammary Paget's disease (EMPD) is controversial. Recently NY-BR-1, a differentiation antigen expressed in the breast and in skin adnexal structures was i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77cfcd6423f06cd0015c2eb4cae5bab3
https://doi.org/10.1111/j.1440-1827.2010.02591.x
https://doi.org/10.1111/j.1440-1827.2010.02591.x
Autor:
Barbara Padberg, Olivier T. Giger, Zsuzsanna Varga, Holger Moch, Christoph Honegger, Elena Lacoste
Publikováno v:
Virchows Archiv. 450:471-474
We describe a phyllodes tumor of borderline malignancy in the labium majus of a 49-year-old woman. The histogenetic origin of phyllodes tumors in the vulva is controversial. Strong immunoreactivity for NY-BR-1, a novel breast differentiation antigen,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::868dd105e192b713dc90db8cac630d1e
https://doi.org/10.1007/s00428-007-0377-8
https://doi.org/10.1007/s00428-007-0377-8
Autor:
Lars C. Huber, Matthias Brock, Hossein Hemmatazad, Olivier T. Giger, Falk Moritz, Michelle Trenkmann, Jörg H. W. Distler, Renate E. Gay, Christoph Kolling, Holger Moch, Beat A. Michel, Steffen Gay, Oliver Distler, Astrid Jüngel
Publikováno v:
Arthritis & Rheumatism. 56:1087-1093
Objective. Rheumatoid arthritis (RA) is a chronic inflammatory disorder of unknown origin. Histone deacetylase (HDA) activity is considered to play a major role in the transcriptional regulation of proinflammatory genes. We undertook this study to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b5b079124089542ef596eb4e7ec1a1
https://doi.org/10.1002/art.22512
https://doi.org/10.1002/art.22512
Autor:
Kirsten D. Mertz, Marco Prinz, Beatriz Navarro, Adriano Aguzzi, Nathalie Braun, Gino Miele, Olivier T. Giger, Ivan Radovanovic
Publikováno v:
The Journal of Neuroscience. 25:4879-4888
The cellular prion protein PrPCconfers susceptibility to transmissible spongiform encephalopathies, yet its normal function is unknown. Although PrPC-deficient mice develop and live normally, expression of amino proximally truncated PrPC(ΔPrP) or of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3de7bcd59dd8ac7cafaef81542cb12
https://doi.org/10.1523/jneurosci.0328-05.2005
https://doi.org/10.1523/jneurosci.0328-05.2005