Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Olivier St-Jean"'
Autor:
Mihaela M. Esanu, Edmund Leung, Nande Wright, Selcuk Calimsiz, Xiang Wang, Olivier St-Jean, Eric A. Standley, Guojun Yu, Li Wang, Dustin Bringley, Roberts Benjamin James, Jaspal Phull, Anna Chiu, Jason A. Davy, Doxsee Ian James, Jeffrey D. Ng, Wen-Tau T. Chang, Lennie Lin, Jenny Phoenix, David Allen Siler, Olga Lapina, Andrea Ambrosi, Youri Kim, Jeffrey A. O. Garber, Jinyu Shen, Bernard Kwong, Keshab Sarma, Bing Shi, Andrew Anthony Martins
Publikováno v:
Organic Process Research & Development. 25:1215-1236
This manuscript describes the chemical process development and multi-kilogram synthesis of rovafovir etalafenamide (GS-9131), a phosphonamidate prodrug nucleotide reverse transcriptase inhibitor un...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e6d25441ec292ea6d90f7f6942f094e
https://doi.org/10.1021/acs.oprd.1c00059
https://doi.org/10.1021/acs.oprd.1c00059
Autor:
Jonah W. Curl, Olivier St-Jean, Jason A. Davy, Olga Lapina, Sangsun Park, Mary Rosario, Jeffrey A. O. Garber, Sura Ha, Bernard Kwong, David Allen Siler, Selcuk Calimsiz, Keshab Sarma, Doxsee Ian James, Jinyu Shen, Jeffrey D. Ng, Lennie Lin, Guojun Yu, Jisung Lee
Publikováno v:
Organic Process Research & Development. 25:1263-1274
Fluorinated nucleoside 1 is a key starting material in the synthesis of rovafovir etalafenamide (2), a novel nucleotide reverse transcriptase inhibitor under development at Gilead Sciences for the ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26f676376f843d7c8975b05c66d15f0f
https://doi.org/10.1021/acs.oprd.1c00026
https://doi.org/10.1021/acs.oprd.1c00026
Autor:
Ghislain Picard, Alain Royer, Benoit Montpetit, Olivier St-Jean-Rondeau, Alexandre Langlois, Alex Mavrovic, Alexandre Roy, Nicolas Marchand
Publikováno v:
The Cryosphere, Vol 10, Iss 2, Pp 623-638 (2016)
The Cryosphere
The Cryosphere, Copernicus 2016, 10 (2), pp.623-638. ⟨10.5194/tc-10-623-2016⟩
The Cryosphere, 2016, 10 (2), pp.623-638. ⟨10.5194/tc-10-623-2016⟩
The Cryosphere
The Cryosphere, Copernicus 2016, 10 (2), pp.623-638. ⟨10.5194/tc-10-623-2016⟩
The Cryosphere, 2016, 10 (2), pp.623-638. ⟨10.5194/tc-10-623-2016⟩
This study aims to better understand and quantify the uncertainties in microwave snow emission models using the Dense Media Radiative Theory Multi-Layer model (DMRT-ML) with in situ measurements of snow properties. We use surface-based radiometric me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3fc3f3dc1e184630c3b2165cda53142
http://www.the-cryosphere.net/10/623/2016/tc-10-623-2016.pdf
http://www.the-cryosphere.net/10/623/2016/tc-10-623-2016.pdf
Autor:
Alexandre Langlois, Alain Royer, Céline Vargel, Alexandre Roy, Ghislain Picard, Vincent Sasseville, Olivier St-Jean-Rondeau
Publikováno v:
Remote Sensing of Environment. 242:111754
Passive microwave (PMW) remote sensing has proven to be a useful approach to characterize the volume of seasonal snowpack in remote northern regions at the synoptic scale. Modeling emitted microwave brightness temperatures (TB) is made possible using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecabab5f5f168bab0ad9d77cbf0aa862
https://doi.org/10.1016/j.rse.2020.111754
https://doi.org/10.1016/j.rse.2020.111754
Publikováno v:
The Journal of Organic Chemistry. 78:2935-2946
The activation and ring-opening of methyl furanosides in the four natural sugar scaffolds (ribo, lyxo, arabino, and xylo) efficiently afforded acyclic thioacetals with high S(N)2-like selectivity at the acetal center in the presence of Me2BBr and thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a926b1889100359e7e4214453f56bdf
https://doi.org/10.1021/jo3027438
https://doi.org/10.1021/jo3027438
Autor:
Vijayaratnam Santhakumar, Tomaszewski Miroslaw, Shujuan Jin, Sandra I. Baltatu, Olivier St-Jean
Publikováno v:
Tetrahedron Letters. 53:1278-1281
Several 3-substituted pyrido[1,2,5]triazepin-4-ones and their benzo counterparts have been prepared in three steps from commercial starting materials. The key step involves S N Ar-type intramolecular nucleophilic aromatic substitution of the appropri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d39a12800951220c26d415486648cf93
https://doi.org/10.1016/j.tetlet.2011.12.132
https://doi.org/10.1016/j.tetlet.2011.12.132
Publikováno v:
Tetrahedron Letters. 47:8275-8278
A series of mono-functionalized trisulfonated phthalocyanines were prepared in aqueous medium under palladium-catalyzed cross-coupling reaction conditions (Sonogashira, Heck and Suzuki) using water-soluble mono-iodo trisufophthalocyanines as precurso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0511d76bd1f6f7499fecfede2085af4a
https://doi.org/10.1016/j.tetlet.2006.09.101
https://doi.org/10.1016/j.tetlet.2006.09.101
Autor:
Sandra I. Baltatu, Shujuan Jin, Tomaszewski Miroslaw, Vijayaratnam Santhakumar, Olivier St-Jean
Publikováno v:
ChemInform. 43
The condensation of ketoamides (I) and (IV) with methyl hydrazine produces hydrazones which undergo intramolecular nucleophilic aromatic substitution to yield the title compounds (III) and their benzo analogues (V).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d42f7d8d83e5c2c4505daba3b6cfb98
https://doi.org/10.1002/chin.201226193
https://doi.org/10.1002/chin.201226193
Publikováno v:
Journal of the American Chemical Society. 132(35)
We are reporting a highly diastereoselective route to 1',2'-cis-nucleoside analogues in the D-ribo, D-lyxo, D-xylo, and D-arabinoside series. Five-membered ring lactols undergo highly selective N-glycosidation reactions in the presence of dimethylbor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c25291aa96002dadab79a9875b788ef
https://pubmed.ncbi.nlm.nih.gov/20704290
https://pubmed.ncbi.nlm.nih.gov/20704290