Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Olivier Raineteau"'
Autor:
Jean-Baptiste Huré, Louis Foucault, Litsa Maria Ghayad, Corentine Marie, Nicolas Vachoud, Lucas Baudouin, Rihab Azmani, Natalija Ivjanin, Alvaro Arevalo-Nuevo, Morgane Pigache, Lamia Bouslama-Oueghlani, Julie-Anne Chemelle, Marie-Aimée Dronne, Raphaël Terreux, Bassem Hassan, François Gueyffier, Olivier Raineteau, Carlos Parras
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Oligodendrocytes are critical for CNS myelin formation and are involved in preterm-birth brain injury (PBI) and multiple sclerosis (MS), both of which lack effective treatments. We present a pharmacogenomic approach that identifies compounds
Externí odkaz:
https://doaj.org/article/f356be8a42664bafb0bc5cc8f418a566
Autor:
Marine Lanfranchi, Sozerko Yandiev, Géraldine Meyer-Dilhet, Salma Ellouze, Martijn Kerkhofs, Raphael Dos Reis, Audrey Garcia, Camille Blondet, Alizée Amar, Anita Kneppers, Hélène Polvèche, Damien Plassard, Marc Foretz, Benoit Viollet, Kei Sakamoto, Rémi Mounier, Cyril F. Bourgeois, Olivier Raineteau, Evelyne Goillot, Julien Courchet
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The cellular mechanisms underlying axonal morphogenesis are essential to the formation of functional neuronal networks. We previously identified the autism-linked kinase NUAK1 as a central regulator of axon branching through the control of m
Externí odkaz:
https://doaj.org/article/4e8f983c4969417aad556f0a4f0dc423
Autor:
Louis Foucault, Timothy Capeliez, Diane Angonin, Celia Lentini, Laurent Bezin, Christophe Heinrich, Carlos Parras, Vanessa Donega, Guillaume Marcy, Olivier Raineteau
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113734- (2024)
Summary: Germinal activity persists throughout life within the ventricular-subventricular zone (V-SVZ) of the postnatal forebrain due to the presence of neural stem cells (NSCs). Accumulating evidence points to a recruitment for these cells following
Externí odkaz:
https://doaj.org/article/94e2692e92984ecd8480dd4def4a48f9
Autor:
Sarah Delcourte, Amel Bouloufa, Renaud Rovera, Cécile Bétry, Erika Abrial, Ouria Dkhissi-Benyahya, Christophe Heinrich, Guillaume Marcy, Olivier Raineteau, Nasser Haddjeri, Guillaume Lucas, Adeline Etiévant
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115384- (2023)
Prefrontal cortex (PFC) inputs to the hippocampus are supposed to be critical in memory processes. Astrocytes are involved in several brain functions, such as homeostasis, neurotransmission, synaptogenesis. However, their role in PFC-mediated modulat
Externí odkaz:
https://doaj.org/article/c470277b3f9d49139288122f37869c11
Low biological fluctuation of mitochondrial CpG and non-CpG methylation at the single-molecule level
Autor:
Chloe Goldsmith, Jesús Rafael Rodríguez-Aguilera, Ines El-Rifai, Adrien Jarretier-Yuste, Valérie Hervieu, Olivier Raineteau, Pierre Saintigny, Victoria Chagoya de Sánchez, Robert Dante, Gabriel Ichim, Hector Hernandez-Vargas
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Mammalian cytosine DNA methylation (5mC) is associated with the integrity of the genome and the transcriptional status of nuclear DNA. Due to technical limitations, it has been less clear if mitochondrial DNA (mtDNA) is methylated and whethe
Externí odkaz:
https://doaj.org/article/4221444650b74227b0be0661a1952aaf
Autor:
Irene Chacon-De-La-Rocha, Gemma Fryatt, Andrea D. Rivera, Alexei Verkhratsky, Olivier Raineteau, Diego Gomez-Nicola, Arthur M. Butt
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Myelin disruption is a feature of natural aging and Alzheimer’s disease (AD). In the CNS, myelin is produced by oligodendrocytes, which are generated throughout life by oligodendrocyte progenitor cells (OPCs). Here, we examined age-related changes
Externí odkaz:
https://doaj.org/article/ebc7e92940f84206acdbdab9960231c5
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract The subventricular zone (SVZ) is a region of ongoing postnatal germinal activity that shows complex spatial heterogeneity. For instance, different SVZ microdomains contain neural stem cells that express distinct transcription factors and gen
Externí odkaz:
https://doaj.org/article/55a332486bb64edfb780c6753d510a09
Autor:
Stefan Zweifel, Guillaume Marcy, Quentin Lo Guidice, Deqiang Li, Christophe Heinrich, Kasum Azim, Olivier Raineteau
Publikováno v:
Stem Cell Reports, Vol 11, Iss 3, Pp 770-783 (2018)
Summary: The largest diversity of neural lineages generated from the subventricular zone (SVZ) occurs early after birth and is regulated in a spatiotemporal manner depending on the expression of specific transcriptional cues. Transcriptomics and fate
Externí odkaz:
https://doaj.org/article/8a1ec823290f496e9d18e7aa1ee07a04
Autor:
Vanessa Donega, Guillaume Marcy, Quentin Lo Giudice, Stefan Zweifel, Diane Angonin, Roberto Fiorelli, Djoher Nora Abrous, Sylvie Rival-Gervier, Muriel Koehl, Denis Jabaudon, Olivier Raineteau
Publikováno v:
Cell Reports, Vol 22, Iss 10, Pp 2567-2574 (2018)
Summary: Progenitors of cortical glutamatergic neurons (Glu progenitors) are usually thought to switch fate before birth to produce astrocytes. We used fate-mapping approaches to show that a large fraction of Glu progenitors persist in the postnatal
Externí odkaz:
https://doaj.org/article/c1710c67106b4d52ae2f5b557d99baf4
Autor:
Kasum Azim, Diane Angonin, Guillaume Marcy, Francesca Pieropan, Andrea Rivera, Vanessa Donega, Claudio Cantù, Gareth Williams, Benedikt Berninger, Arthur M Butt, Olivier Raineteau
Publikováno v:
PLoS Biology, Vol 15, Iss 3, p e2000698 (2017)
Strategies for promoting neural regeneration are hindered by the difficulty of manipulating desired neural fates in the brain without complex genetic methods. The subventricular zone (SVZ) is the largest germinal zone of the forebrain and is responsi
Externí odkaz:
https://doaj.org/article/2fe17744e91c4e988c0ac4cdb90fb697