Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Olivier Provot"'
Publikováno v:
Pharmaceuticals, Vol 14, Iss 8, p 779 (2021)
This review concerns the synthesis and biological activities of pyrazino[1,2-a]indoles and pyrazino[1,2-a]indol-1-ones reported since 1997 and the discovery of biological activity of pyrazinoindole derivatives. In the first part, we first presented t
Externí odkaz:
https://doaj.org/article/eb6bde94853b4f2c9e4dd6b5c8f6fede
Autor:
Camille Hauguel, Christine Tran, Olivier Provot, Jérôme Bignon, Vincent Gandon, Abdallah Hamze
Publikováno v:
Advanced Synthesis & Catalysis. 364:3004-3015
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98b0693214a061ddb01c6f39db2d8667
https://doi.org/10.1002/adsc.202200550
https://doi.org/10.1002/adsc.202200550
Publikováno v:
Advanced Synthesis & Catalysis. 364:1613-1619
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3ca75c6ac3f5d03577f41e1d6dd8f50
https://doi.org/10.1002/adsc.202200153
https://doi.org/10.1002/adsc.202200153
Autor:
Romain Hany, Jean-Philippe Leyris, Guillaume Bret, Sylvie Mallié, Chamroeun Sar, Maxime Thouaye, Abdallah Hamze, Olivier Provot, Pierre Sokoloff, Jean Valmier, Pascal Villa, Didier Rognan
Publikováno v:
ACS Chemical Biology
ACS Chemical Biology, 2022, 17 (3), pp.709-722. ⟨10.1021/acschembio.2c00048⟩
ACS Chemical Biology, 2022, 17 (3), pp.709-722. ⟨10.1021/acschembio.2c00048⟩
International audience; nhibiting receptor tyrosine kinases is commonly achieved by two main strategies targeting either the intracellular kinase domain by low molecular weight compounds or the extracellular ligand-binding domain by monoclonal antibo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f41fdf03a3233fc02562674c1e8cbb35
https://doi.org/10.1021/acschembio.2c00048
https://doi.org/10.1021/acschembio.2c00048
Publikováno v:
The Journal of Organic Chemistry. 87:1249-1261
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35a7b0d9710e142ea13b230e5825b47c
https://doi.org/10.1021/acs.joc.1c02580
https://doi.org/10.1021/acs.joc.1c02580
Publikováno v:
Asian Journal of Organic Chemistry. 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a0be1f961e6ec58d5926b7ff1377334
https://doi.org/10.1002/ajoc.202200306
https://doi.org/10.1002/ajoc.202200306
Publikováno v:
Organic & Biomolecular Chemistry. 19:5358-5367
A new methodology to synthesize sulfonyl-N-phenylaniline derivatives via the trapping of bromo-sulfone derivatives generated from N-tosylhydrazones (NTHs) with amines is described. The reaction proved successful for a wide range of NTHs and amines an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa65be7e1a844e757dd5ba89583573c
https://doi.org/10.1039/d1ob00676b
https://doi.org/10.1039/d1ob00676b
Publikováno v:
European Journal of Organic Chemistry. 2022
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58cc7011c76303283059cc031a8ed1be
https://doi.org/10.1002/ejoc.202101460
https://doi.org/10.1002/ejoc.202101460
Autor:
Camille Hauguel, Sarah Ducellier, Olivier Provot, Nada Ibrahim, Diana Lamaa, Coline Balcerowiak, Boris Letribot, Megane Nascimento, Vincent Blanchard, Laurie Askenatzis, Helene Levaique, Jérôme Bignon, Francesco Baschieri, Cyril Bauvais, Guillaume Bollot, Dolor Renko, Alain Deroussent, Bastien Prost, Marie-Catherine Laisne, Sophie Michallet, Laurence Lafanechère, Sébastien Papot, Guillaume Montagnac, Christine Tran, Mouad Alami, Sebastien Apcher, Abdallah Hamze
Publikováno v:
European Journal of Medicinal Chemistry. 240:114573
A series of quinoline and quinazoline analogs were designed and synthesized as new tubulin polymerization (TP) and histone deacetylases (HDAC) inhibitors. Compounds 12a and 12d showed the best cytotoxicity activities against a panel of human cancer c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7336a68864efb3226acaab439909276
https://doi.org/10.1016/j.ejmech.2022.114573
https://doi.org/10.1016/j.ejmech.2022.114573
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2021, 224, pp.113728. ⟨10.1016/j.ejmech.2021.113728⟩
European Journal of Medicinal Chemistry, Elsevier, 2021, 224, pp.113728. ⟨10.1016/j.ejmech.2021.113728⟩
International audience; This review brings together the various pathways to the oxazino[4,3-a]indole motif over the last decades. Representative examples showing the scope of these processes will illustrate the synthetic pathways and the biological a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2a6e34ffd3520620abee8485c36383
https://pubmed.ncbi.nlm.nih.gov/34340043
https://pubmed.ncbi.nlm.nih.gov/34340043