Zobrazeno 1 - 10
of 309
pro vyhledávání: '"Olivier Poch"'
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2023)
Protein annotation errors can have significant consequences in a wide range of fields, ranging from protein structure and function prediction to biomedical research, drug discovery, and biotechnology. By comparing the domains of different proteins, s
Externí odkaz:
https://doaj.org/article/54419616923b41a4894ea727592a1fa9
Autor:
Nicolas Scalzitti, Arnaud Kress, Romain Orhand, Thomas Weber, Luc Moulinier, Anne Jeannin-Girardon, Pierre Collet, Olivier Poch, Julie D. Thompson
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-26 (2021)
Abstract Background Ab initio prediction of splice sites is an essential step in eukaryotic genome annotation. Recent predictors have exploited Deep Learning algorithms and reliable gene structures from model organisms. However, Deep Learning methods
Externí odkaz:
https://doaj.org/article/dae123c3bbd74e8ba53ff17599644662
Autor:
Claudine Mayer, Arthur Vogt, Tuba Uslu, Nicolas Scalzitti, Kirsley Chennen, Olivier Poch, Julie D. Thompson
Publikováno v:
Journal of Fungi, Vol 9, Iss 4, p 424 (2023)
In fungi, the most abundant transcription factor (TF) class contains a fungal-specific ‘GAL4-like’ Zn2C6 DNA binding domain (DBD), while the second class contains another fungal-specific domain, known as ‘fungal_trans’ or middle homology doma
Externí odkaz:
https://doaj.org/article/c334065c4b9840bc8c0f979c166c269f
Autor:
Stefan E. Schröder, Olivier Poch, Marco Ferrari, Simone De Angelis, Robin Sultana, Sandra M. Potin, Pierre Beck, Maria Cristina De Sanctis, Bernard Schmitt
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
The origin of blue ejecta around the fresh craters of dwarf planet Ceres is unknown. Here, the authors show that the blue color results from high porosity of the surface, induced by sublimation of ice-phyllosilicate mixture produced by impacts.
Externí odkaz:
https://doaj.org/article/4b2db4ce986b48a99005da7f15e656de
Autor:
Corentin Meyer, Nicolas Scalzitti, Anne Jeannin-Girardon, Pierre Collet, Olivier Poch, Julie D. Thompson
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-16 (2020)
Abstract Background Recent advances in sequencing technologies have led to an explosion in the number of genomes available, but accurate genome annotation remains a major challenge. The prediction of protein-coding genes in eukaryotic genomes is espe
Externí odkaz:
https://doaj.org/article/4ff9dc6c60514537a4d4fda28cb2cadd
Publikováno v:
Virology Journal, Vol 17, Iss 1, Pp 1-13 (2020)
Abstract Background The Covid19 infection is caused by the SARS-CoV-2 virus, a novel member of the coronavirus (CoV) family. CoV genomes code for a ORF1a / ORF1ab polyprotein and four structural proteins widely studied as major drug targets. The geno
Externí odkaz:
https://doaj.org/article/33c049d56eb64f1d942f1e729e8e1a31
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-20 (2020)
Abstract Background The draft genome assemblies produced by new sequencing technologies present important challenges for automatic gene prediction pipelines, leading to less accurate gene models. New benchmark methods are needed to evaluate the accur
Externí odkaz:
https://doaj.org/article/c8993dd4c1674c38a87527c063639d10
Autor:
Kirsley Chennen, Thomas Weber, Xavière Lornage, Arnaud Kress, Johann Böhm, Julie Thompson, Jocelyn Laporte, Olivier Poch
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236962 (2020)
The diffusion of next-generation sequencing technologies has revolutionized research and diagnosis in the field of rare Mendelian disorders, notably via whole-exome sequencing (WES). However, one of the main issues hampering achievement of a diagnosi
Externí odkaz:
https://doaj.org/article/b32e890b69c64902a068518e1158ea3a
Publikováno v:
Bioinformatics and Biology Insights, Vol 2013, Iss 7, Pp 119-131 (2013)
Externí odkaz:
https://doaj.org/article/32e6ab32e2c84c5baa6c6c519ae91561
Autor:
Christo Kole, Naomi Berdugo, Corinne Da Silva, Najate Aït-Ali, Géraldine Millet-Puel, Delphine Pagan, Frédéric Blond, Laetitia Poidevin, Raymond Ripp, Valérie Fontaine, Patrick Wincker, Donald J Zack, José-Alain Sahel, Olivier Poch, Thierry Léveillard
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150758 (2016)
To investigate the complexity of alternative splicing in the retina, we sequenced and analyzed a total of 115,706 clones from normalized cDNA libraries from mouse neural retina (66,217) and rat retinal pigmented epithelium (49,489). Based upon cluste
Externí odkaz:
https://doaj.org/article/d9109d8f0e3c4b10bd2ca4732e1ae3d7