Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Olivier Nosjean"'
Autor:
Céline Legros, Clémence Dupré, Chantal Brasseur, Anne Bonnaud, Olivier Bruno, Damien Valour, Preety Shabajee, Adeline Giganti, Olivier Nosjean, Terrence P. Kenakin, Jean A. Boutin
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 1, Pp n/a-n/a (2020)
Abstract Melatonin is a neurohormone that translates the circadian rhythm to the peripheral organs through a series of binding sites identified as G protein‐coupled receptors MT1 and MT2. Due to minute amounts of receptor proteins in target organs,
Externí odkaz:
https://doaj.org/article/08643ceb060e4077bb6c6bb5129fe136
Autor:
Célia Gautier, Sophie-Penelope Guenin, Isabelle Riest-Fery, Tahlia Jade Perry, Céline Legros, Olivier Nosjean, Valerie Simonneaux, Frank Grützner, Jean A Boutin
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0191904 (2018)
Melatonin is a neurohormone produced in both animals and plants. It binds at least three G-protein-coupled receptors: MT1 and MT2, and Mel1cGPR. Mammalian GPR50 evolved from the reptilian/avian Mel1c and lost its capacity to bind melatonin in all the
Externí odkaz:
https://doaj.org/article/00b44f120b614522bcb5cec91c6fac2f
Autor:
Olivier Nosjean, Jean A. Boutin, Jean-Louis Brayer, Philippe Delagrange, Daniel-Henri Caignard, Gérald Guillaumet, Pascal Berthelot, François Lefoulon, Emmanuel Thomas, Franck Suzenet, Benoît Folleas, Saïd Yous, Werner Hassler, Teresa Grelak, Sandrine Pedragona-Moreau, Ulrich Matthey, Céline Legros
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 5, Pp 8948-8962 (2013)
Melatonin receptors have been studied for several decades. The low expression of the receptors in tissues led the scientific community to find a substitute for the natural hormone melatonin, the agonist 2-[125I]-iodomelatonin. Using the agonist, seve
Externí odkaz:
https://doaj.org/article/c83100bfbad24ccf9a15b968e6702509
Autor:
Célia Gautier, Emilie Dufour, Clémence Dupré, Giulia Lizzo, Sarah Caignard, Isabelle Riest-Fery, Chantal Brasseur, Céline Legros, Philippe Delagrange, Olivier Nosjean, Valérie Simonneaux, Jean A. Boutin, Sophie-Pénélope Guenin
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 7, p 1957 (2018)
For many years, it was of interest to identify the sequences encoding the two melatonin receptors (MT1 and MT2) from various species. After publishing the basic molecular characterization of the human, rat, mouse, sheep, and platypus MT1, MT2, or Mel
Externí odkaz:
https://doaj.org/article/3a1d8bb090f143ef935822001e658ada
Autor:
Christel Logez, Sylvie Berger, Céline Legros, Jean-Louis Banères, William Cohen, Philippe Delagrange, Olivier Nosjean, Jean A Boutin, Gilles Ferry, Frédéric Simonin, Renaud Wagner
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100616 (2014)
The human melatonin MT1 receptor-belonging to the large family of G protein-coupled receptors (GPCRs)-plays a key role in circadian rhythm regulation and is notably involved in sleep disorders and depression. Structural and functional information at
Externí odkaz:
https://doaj.org/article/961a2e8080f24c94a99bea2e9fb8eaad
Autor:
Kim Vietz Andreassen, Sara Toftegaard Hjuler, Sebastian G Furness, Patrick M Sexton, Arthur Christopoulos, Olivier Nosjean, Morten Asser Karsdal, Kim Henriksen
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92042 (2014)
Salmon calcitonin (sCT) and human calcitonin (hCT) are pharmacologically distinct. However, the reason for the differences is unclear. Here we analyze the differences between sCT and hCT on the human calcitonin receptor (CT(a)R) with respect to activ
Externí odkaz:
https://doaj.org/article/91614874790a494dabe08967edbb8255
Autor:
Meng Zhang, Yang Feng, Jia Wang, Jianwei Zhao, Ting Li, Min He, Dehua Yang, Olivier Nosjean, Jean Boutin, Pierre Renard, Ming-Wei Wang
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63861 (2013)
G protein-coupled receptor 119 (GPR119) is highly expressed in pancreatic β cells and enteroendocrine cells. It is involved in glucose-stimulated insulin secretion and glucagon-like peptide-1 (GLP-1) release, thereby representing a promising target
Externí odkaz:
https://doaj.org/article/2d1f7b70783544f58596b3e5950cdb97
Autor:
Céline Legros, Anne Rojas, Clémence Dupré, Chantal Brasseur, Isabelle Riest‐Fery, Olivier Muller, Jean‐Claude Ortuno, Olivier Nosjean, Sophie‐Pénélope Guenin, Gilles Ferry, Jean A. Boutin
Publikováno v:
Protein Science. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f7585e91b40eb6f6fad9ab4d81cab0b
https://doi.org/10.1002/pro.4459
https://doi.org/10.1002/pro.4459
Autor:
Céline, Legros, Anne, Rojas, Clémence, Dupré, Chantal, Brasseur, Isabelle, Riest-Fery, Olivier, Muller, Jean-Claude, Ortuno, Olivier, Nosjean, Sophie-Pénélope, Guenin, Gilles, Ferry, Jean A, Boutin
Publikováno v:
Protein science : a publication of the Protein Society. 31(12)
D3/D2 sub-specificity is a complex problem to solve. Indeed, in the absence of easy structural biology of the G-protein coupled receptors, and despite key progresses in this area, the systematic knowledge of the ligand/receptor relationship is diffic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dc1121ec1d7b67bf067023180e1d39df
https://pubmed.ncbi.nlm.nih.gov/36177735
https://pubmed.ncbi.nlm.nih.gov/36177735
Autor:
Ming-Wei Wang, Olivier Nosjean, Alicia X. Deng, Yan Zhou, Jean A. Boutin, Xiaoqing Cai, Pierre Renard, Jia Wang, Dehua Yang, Dao‐Hai Du, Cheng Luo
Publikováno v:
Chemical biologydrug designREFERENCES. 96(4)
Enhancer of zeste homolog 2 (EZH2) is the catalytic subunit of the polycomb repressive complex 2 (PRC2) along with embryonic ectoderm development (EED) and suppressor of zeste 12 (SUZ12), which implements transcriptional repression mainly by depositi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74cc84bc522e2e1e58c38907bc54ba8b
https://pubmed.ncbi.nlm.nih.gov/32394628
https://pubmed.ncbi.nlm.nih.gov/32394628