Zobrazeno 1 - 10
of 211
pro vyhledávání: '"Olivier Neyrolles"'
Autor:
Giulia Trimaglio, Tamara Sneperger, Benjamin B. A. Raymond, Nelly Gilles, Emmanuelle Näser, Marie Locard-Paulet, Marieke E. Ijsselsteijn, Thomas P. Brouwer, Romain Ecalard, Jessica Roelands, Naoki Matsumoto, André Colom, Myriam Habch, Noel F. C. C. de Miranda, Nathalie Vergnolle, Christel Devaud, Olivier Neyrolles, Yoann Rombouts
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Development and progression of malignancies are accompanied and influenced by alterations in the surrounding immune microenvironment. Understanding the cellular and molecular interactions between immune cells and cancer cells has not only pr
Externí odkaz:
https://doaj.org/article/f3225b2dcc7a4c39953c371ada897c96
Autor:
Mariano Maio, Joaquina Barros, Marine Joly, Zoi Vahlas, José Luis Marín Franco, Melanie Genoula, Sarah C Monard, María Belén Vecchione, Federico Fuentes, Virginia Gonzalez Polo, María Florencia Quiroga, Mónica Vermeulen, Thien-Phong Vu Manh, Rafael J Argüello, Sandra Inwentarz, Rosa Musella, Lorena Ciallella, Pablo González Montaner, Domingo Palmero, Geanncarlo Lugo Villarino, María del Carmen Sasiain, Olivier Neyrolles, Christel Vérollet, Luciana Balboa
Publikováno v:
eLife, Vol 12 (2024)
During tuberculosis (TB), migration of dendritic cells (DCs) from the site of infection to the draining lymph nodes is known to be impaired, hindering the rapid development of protective T-cell-mediated immunity. However, the mechanisms involved in t
Externí odkaz:
https://doaj.org/article/06be5d42f56e4b37b72a04859463ae2d
Autor:
Alexandra Maure, Emeline Lawarée, Francesco Fiorentino, Alexandre Pawlik, Saideep Gona, Alexandre Giraud-Gatineau, Matthew J G Eldridge, Anne Danckaert, David Hardy, Wafa Frigui, Camille Keck, Claude Gutierrez, Olivier Neyrolles, Nathalie Aulner, Antonello Mai, Mélanie Hamon, Luis B Barreiro, Priscille Brodin, Roland Brosch, Dante Rotili, Ludovic Tailleux
Publikováno v:
PLoS Biology, Vol 22, Iss 4, p e3002259 (2024)
Antituberculosis drugs, mostly developed over 60 years ago, combined with a poorly effective vaccine, have failed to eradicate tuberculosis. More worryingly, multiresistant strains of Mycobacterium tuberculosis (MTB) are constantly emerging. Innovati
Externí odkaz:
https://doaj.org/article/e2eedf80218b48f79d34efc207ddd2fb
Autor:
Xibing Xu, Ben Usher, Claude Gutierrez, Roland Barriot, Tom J. Arrowsmith, Xue Han, Peter Redder, Olivier Neyrolles, Tim R. Blower, Pierre Genevaux
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Mycobacterium tuberculosis, the bacterium responsible for human tuberculosis, has a genome encoding a remarkably high number of toxin-antitoxin systems of largely unknown function. We have recently shown that the M. tuberculosis genome encod
Externí odkaz:
https://doaj.org/article/192b7c0f9cc2492486b0eb24b655df5a
Autor:
Rossella Bellini, Annalisa Moregola, Jasmine Nour, Yoann Rombouts, Olivier Neyrolles, Patrizia Uboldi, Fabrizia Bonacina, Giuseppe Danilo Norata
Publikováno v:
Atherosclerosis Plus, Vol 51, Iss , Pp 8-12 (2023)
Background and aims: Atherogenesis results from altered lipid metabolism and impaired immune response. Emerging evidence has suggested that dendritic cells (DCs) participate to atherosclerosis-related immune response, but their impact is scarcely cha
Externí odkaz:
https://doaj.org/article/f2666e69875e4abe80fc3786cf0cd27b
Autor:
Marianne Martin, Angelique deVisch, Yves-Marie Boudehen, Philippe Barthe, Claude Gutierrez, Obolbek Turapov, Talip Aydogan, Laurène Heriaud, Jerome Gracy, Olivier Neyrolles, Galina V. Mukamolova, François Letourneur, Martin Cohen-Gonsaud
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Host metabolism reprogramming is a key feature of Mycobacterium tuberculosis (Mtb) infection that enables the survival of this pathogen within phagocytic cells and modulates the immune response facilitating the spread of the tuberculosis dis
Externí odkaz:
https://doaj.org/article/763b7a4b323d4291b24cc83a94b4a85f
Autor:
Yves-Marie Boudehen, Marion Faucher, Xavier Maréchal, Roger Miras, Jérôme Rech, Yoann Rombouts, Olivier Sénèque, Maximilian Wallat, Pascal Demange, Jean-Yves Bouet, Olivier Saurel, Patrice Catty, Claude Gutierrez, Olivier Neyrolles
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The human pathogen Mycobacterium tuberculosis requires a metal exporter, CtpC, for resistance to zinc poisoning. Here, the authors show that zinc resistance also depends on a chaperone-like protein that binds zinc ions, forms high-molecular-weight co
Externí odkaz:
https://doaj.org/article/f8d56618347d41b3aa4b720a1e70773b
Autor:
Yoann Rombouts, Olivier Neyrolles
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 6 (2023)
Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), infects primarily macrophages, causing them to differentiate into lipid-laden foamy macrophages that are a primary source of tissue destruction in patients with TB. In this issue o
Externí odkaz:
https://doaj.org/article/af9b786937c4456f84c90347deb5d946
Autor:
Jasmine Nour, Annalisa Moregola, Monika Svecla, Lorenzo Da Dalt, Rossella Bellini, Olivier Neyrolles, Gian Paolo Fadini, Yoann Rombouts, Mattia Albiero, Fabrizia Bonacina, Giuseppe Danilo Norata
Publikováno v:
Metabolites, Vol 12, Iss 12, p 1205 (2022)
The mannose receptor C-type 1 (Mrc1) is a C-type lectin receptor expressed on the immune cells and sinusoidal endothelial cells (ECs) of several tissues, including the bone marrow (BM). Parallel to systemic metabolic alterations and hematopoietic cel
Externí odkaz:
https://doaj.org/article/b4499337f4174e78a709d4c4a62b9f81
Autor:
Yves-Marie Boudehen, Maximilian Wallat, Philippe Rousseau, Olivier Neyrolles, Claude Gutierrez
Publikováno v:
BioTechniques, Vol 68, Iss 2, Pp 106-110 (2020)
Xer-cise is a technique using antibiotic resistance cassettes flanked by dif sites allowing spontaneous and accurate excision from bacterial chromosomes with a high frequency through the action of the cellular recombinase XerCD. Here, we report a sig
Externí odkaz:
https://doaj.org/article/6a91933f70014fcb8a18d0bd33cfbcf9