Renal transplant immunosuppression impairs natural killer cell function in vitro and in vivo.

Autor: Olivier Morteau, Samkeliso Blundell, Aron Chakera, Sophia Bennett, Charita M Christou, Philip D Mason, Richard J Cornall, Christopher A O'Callaghan

Publikováno v: PLoS ONE, Vol 5, Iss 10, p e13294 (2010)

Despite an increasing awareness of the importance of innate immunity, the roles of natural killer (NK) cells in transplant rejection and antiviral and cancer immunity during immunosuppression have not been clearly defined.To address this issue we hav

Externí odkaz: https://doaj.org/article/df251f31bad24b8f81eabafa329a224d

Elevated Vasoactive Intestinal Peptide Concentrations in Patients with Irritable Bowel Syndrome

Autor: Olivier Morteau, William E. Whitehead, Olafur S. Palsson, David A. Johnson, John T. Woosley, Michael J. Davies, Eugene M. Bozymski, Marsha J. Turner, R. Balfour Sartor

Publikováno v: Digestive Diseases and Sciences. 49:1236-1243

The aim was to assess the roles of gut hormones and immune dysfunction in irritable bowel. In Study I, rectal mucosal samples examined blindly showed no histological evidence of inflammation in 16 irritable bowel patients compared to 17 healthy contr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a538aad1bff3335c1748c6695647e35b
https://doi.org/10.1023/b:ddas.0000037818.64577.ef

Protective effects of neurokinin-1 receptor during colitis in mice: role of the epidermal growth factor receptor

Autor: L Valenick, Jeff Zacks, Bao Lu, Charalabos Pothoulakis, Olivier Morteau, Ignazio Castagliuolo, Np Gerard, Cc Wang, Ac Keates

Publikováno v: British Journal of Pharmacology. 136:271-279

1. The role of substance P and its high affinity neurokinin-1 receptor in colitis has not been fully elucidated. We assessed the participation of neurokinin-1 receptor in colitis using the 2,4,6,-trinitrobenzensulphonic acid and dextran sulphate-indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7625209f402def27a95dcce5b61e4c0a
https://doi.org/10.1038/sj.bjp.0704697

The Phenotype of Circulating Follicular-Helper T Cells in Patients with Rheumatoid Arthritis Defines CD200 as a Potential Therapeutic Target

Autor: Richard J. Cornall, Raashid Luqmani, Sophia C. Bennett, Paul Bowness, Aron Chakera, Olivier Morteau

Publikováno v: Clinical and Developmental Immunology
Chakera, A, Bennett, S C, Morteau, O, Bowness, P, Luqmani, R A & Cornall, R J 2012, ' The phenotype of circulating follicular-helper T cells in patients with rheumatoid arthritis defines CD200 as a potential therapeutic target ', Clinical and Developmental Immunology . https://doi.org/10.1155/2012/948218
Clinical and Developmental Immunology, Vol 2012 (2012)

Rheumatoid arthritis (RA) is a systemic autoimmune disease primarily affecting synovial joints in which the development of autoantibodies represents a failure of normal tolerance mechanisms, suggesting a role for follicular helper T cells (TFH) in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386b26e8bac94868a651e615e6f1eada

Involvement of neurokinin 1 and 2 receptors in viscerosensitive response to rectal distension in rats

Autor: Lionel Bueno, Olivier Morteau, Véronique Julia

Publikováno v: Gastroenterology
Gastroenterology, WB Saunders, 1994, 107, pp.94-102

Background/Aims: Tachykinins participate in somatic pain and intestinal motility control. The role of tachykinin receptors in both colonic motor disturbances and visceral pain (abdominal contractions as an index of visceral pain) induced by rectal di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f926a7b0ab29680b34fa43ebd801b921
https://pubmed.ncbi.nlm.nih.gov/7517374