Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Olivier Moralès"'
Autor:
Anthony Lefebvre, Camille Trioën, Sarah Renaud, William Laine, Benjamin Hennart, Clément Bouchez, Bertrand Leroux, Delphine Allorge, Jérôme Kluza, Elisabeth Werkmeister, Guillaume Paul Grolez, Nadira Delhem, Olivier Moralès
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 12, Pp n/a-n/a (2023)
Abstract Nasopharyngeal carcinoma‐derived small extracellular vesicles (NPCSEVs) have an immunosuppressive impact on the tumour microenvironment. In this study, we investigated their influence on the generation of tolerogenic dendritic cells and th
Externí odkaz:
https://doaj.org/article/15bbc9120a924f3ab8aab4e6fc2461a7
Autor:
Alexandre Quilbe, Rami Mustapha, Belinda Duchêne, Abhishek Kumar, Elisabeth Werkmeister, Emmanuelle Leteurtre, Olivier Moralès, Nicolas Jonckheere, Isabelle Van Seuningen, Nadira Delhem
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundPancreatic adenocarcinoma (PDAC) is a devastating disease with an urgent need for therapeutic innovation. Immune checkpoint inhibition has shown promise in a variety of solid tumors, but most clinical trials have failed to demonstrate clini
Externí odkaz:
https://doaj.org/article/b5d1cdad42af40cfbbd8dc03480fea9b
Autor:
Martha Baydoun, Léa Boidin, Bertrand Leroux, Anne-Sophie Vignion-Dewalle, Alexandre Quilbe, Guillaume Paul Grolez, Henri Azaïs, Céline Frochot, Olivier Moralès, Nadira Delhem
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11288 (2023)
Photodynamic therapy (PDT) has shown improvements in cancer treatment and in the induction of a proper anti-tumor immune response. However, current photosensitizers (PS) lack tumor specificity, resulting in reduced efficacy and side effects in patien
Externí odkaz:
https://doaj.org/article/6cf71feec7d94fde944203569ac81e79
An Efficient 5-Aminolevulinic Acid Photodynamic Therapy Treatment for Human Hepatocellular Carcinoma
Autor:
Abhishek Kumar, Florian Pecquenard, Martha Baydoun, Alexandre Quilbé, Olivier Moralès, Bertrand Leroux, Lynda Aoudjehane, Filomena Conti, Emmanuel Boleslawski, Nadira Delhem
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10426 (2023)
Photodynamic therapy (PDT) is a two-stage treatment relying on cytotoxicity induced by photoexcitation of a nontoxic dye, called photosensitizer (PS). Using 5-aminolevulinic acid (5-ALA), the pro-drug of PS protoporphyrin IX, we investigated the impa
Externí odkaz:
https://doaj.org/article/e1c9b49f77194fc2af4a8c6f0447bb41
Publikováno v:
Cancers, Vol 13, Iss 20, p 5176 (2021)
Photodynamic Therapy (PDT) relies on local or systemic administration of a light-sensitive dye, called photosensitizer, to accumulate into the target site followed by excitation with light of appropriate wavelength and fluence. This photo-activated m
Externí odkaz:
https://doaj.org/article/2ee91d482bda4956b258d9b1cfc2ccca
Autor:
Clara Milhem, Olivier Moralès, Céline Ingelaere, David Pasquier, Serge Mordon, Laurent Mortier, Xavier Mirabel, Nadira Delhem
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6772 (2020)
The development of immunotherapy has recently modified the anti-tumor therapeutic arsenal; particularly, immune checkpoint inhibitors have led to a significant increase in overall survival. The current challenge is now to select good responder patien
Externí odkaz:
https://doaj.org/article/cec0f850ab16444ea9dae3912b76f0b3
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 12, p 4292 (2020)
Nasopharyngeal carcinoma (NPC) is a malignant tumour of the head and neck affecting localised regions of the world, with the highest rates described in Southeast Asia, Northern Africa, and Greenland. Its high morbidity rate is linked to both late-sta
Externí odkaz:
https://doaj.org/article/d2fa50a84d5243e69cc0f76d249ab11b
Autor:
Martha Baydoun, Olivier Moralès, Céline Frochot, Colombeau Ludovic, Bertrand Leroux, Elise Thecua, Laurine Ziane, Anne Grabarz, Abhishek Kumar, Clémentine de Schutter, Pierre Collinet, Henri Azais, Serge Mordon, Nadira Delhem
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 4, p 1185 (2020)
Often discovered at an advanced stage, ovarian cancer progresses to peritoneal carcinoma, which corresponds to the invasion of the serosa by multiple tumor implants. The current treatment is based on the combination of chemotherapy and tumor cytoredu
Externí odkaz:
https://doaj.org/article/1d3f25ce5f104281a925fca19c13f639
Autor:
Alexandre Quilbe, Olivier Moralès, Martha Baydoun, Abhishek Kumar, Rami Mustapha, Takashi Murakami, Bertrand Leroux, Clémentine de Schutter, Elise Thecua, Laurine Ziane, Ludovic Colombeau, Céline Frochot, Serge Mordon, Nadira Delhem
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 1, p 192 (2020)
To date, pancreatic adenocarcinoma (ADKP) is a devastating disease for which the incidence rate is close to the mortality rate. The survival rate has evolved only 2−5% in 45 years, highlighting the failure of current therapies. Otherwise, the use o
Externí odkaz:
https://doaj.org/article/22ff5a3083d6439cbf8a77ca51fc1440
Autor:
Laurissa Ouaguia, Olivier Moralès, Lynda Aoudjehane, Czeslaw Wychowski, Abhishek Kumar, Jean Dubuisson, Yvon Calmus, Filomena Conti, Nadira Delhem
Publikováno v:
Cells, Vol 8, Iss 10, p 1296 (2019)
Background: The role of regulatory T cells (Tregs) is now well established in the progression of hepatocellular carcinoma (HCC) linked to Hepatitis C virus (HCV) infection. However, nothing is known about the potential interplay between Tregs and HCV
Externí odkaz:
https://doaj.org/article/85ace2fa72384fdcafbcffb79929fc62