Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Olivier Marre"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract A fundamental task for the brain is to generate predictions of future sensory inputs, and signal errors in these predictions. Many neurons have been shown to signal omitted stimuli during periodic stimulation, even in the retina. However, th
Externí odkaz:
https://doaj.org/article/1da4c53bb1ee4983b0b21af9f979a546
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 4, p e1011965 (2024)
The efficient coding hypothesis posits that early sensory neurons transmit maximal information about sensory stimuli, given internal constraints. A central prediction of this theory is that neurons should preferentially encode stimuli that are most s
Externí odkaz:
https://doaj.org/article/b74cc17f7cce4b7aae943d1001890f1c
Autor:
Hanen Khabou, Elaine Orendorff, Francesco Trapani, Marco Rucli, Melissa Desrosiers, Pierre Yger, Deniz Dalkara, Olivier Marre
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 31, Iss , Pp 101107- (2023)
Most inherited retinal dystrophies display progressive photoreceptor cell degeneration leading to severe visual impairment. Optogenetic reactivation of inner retinal neurons is a promising avenue to restore vision in retinas having lost their photore
Externí odkaz:
https://doaj.org/article/b78a68eae9bd436db9cd81cc7fa020a7
Autor:
Matías A. Goldin, Baptiste Lefebvre, Samuele Virgili, Mathieu Kim Pham Van Cang, Alexander Ecker, Thierry Mora, Ulisse Ferrari, Olivier Marre
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Ganglion cells classically respond to either light increase (ON) or decrease (OFF). Here, the authors show that during natural scene stimulation, a single ganglion cell can switch between ON and OFF depending on the visual context.
Externí odkaz:
https://doaj.org/article/317b2db53ec24a87aa789833a613a490
Autor:
Gregory Gauvain, Himanshu Akolkar, Antoine Chaffiol, Fabrice Arcizet, Mina A. Khoei, Mélissa Desrosiers, Céline Jaillard, Romain Caplette, Olivier Marre, Stéphane Bertin, Claire-Maelle Fovet, Joanna Demilly, Valérie Forster, Elena Brazhnikova, Philippe Hantraye, Pierre Pouget, Anne Douar, Didier Pruneau, Joël Chavas, José-Alain Sahel, Deniz Dalkara, Jens Duebel, Ryad Benosman, Serge Picaud
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Gauvain et al demonstrate that optogenetic therapy using the AAV2.7m8- ChR-tdT construct can partially restore vision in non-human primates to levels above those considered legally-blind. This study enables the identification of the most suitable con
Externí odkaz:
https://doaj.org/article/0b4ca90d06f64da69afaff7c49d68f90
Autor:
Baptiste Wilmet, Jacques Callebert, Robert Duvoisin, Ruben Goulet, Christophe Tourain, Christelle Michiels, Helen Frederiksen, Frank Schaeffel, Olivier Marre, José Alain Sahel, Isabelle Audo, Serge Picaud, Christina Zeitz
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 219 (2022)
Mutations in GPR179 are one of the most common causes of autosomal recessive complete congenital stationary night blindness (cCSNB). This retinal disease is characterized in patients by impaired dim and night vision, associated with other ocular symp
Externí odkaz:
https://doaj.org/article/4c142a67c30449f4abe5defc1db7bbd5
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 1, p e1008501 (2021)
A major goal in neuroscience is to understand how populations of neurons code for stimuli or actions. While the number of neurons that can be recorded simultaneously is increasing at a fast pace, in most cases these recordings cannot access a complet
Externí odkaz:
https://doaj.org/article/d47584b49ae741ca92feb8c41b17ccc2
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0248940 (2021)
A central goal in systems neuroscience is to understand the functions performed by neural circuits. Previous top-down models addressed this question by comparing the behaviour of an ideal model circuit, optimised to perform a given function, with neu
Externí odkaz:
https://doaj.org/article/09ae7e81c1cd4348a56066fe07a7c988
Autor:
Ulisse Ferrari, Stéphane Deny, Abhishek Sengupta, Romain Caplette, Francesco Trapani, José-Alain Sahel, Deniz Dalkara, Serge Picaud, Jens Duebel, Olivier Marre
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 7, p e1007857 (2020)
In many cases of inherited retinal degenerations, ganglion cells are spared despite photoreceptor cell death, making it possible to stimulate them to restore visual function. Several studies have shown that it is possible to express an optogenetic pr
Externí odkaz:
https://doaj.org/article/c8801f81e8ab440e96c42196db38a4d5
Autor:
Stéphane Deny, Ulisse Ferrari, Emilie Macé, Pierre Yger, Romain Caplette, Serge Picaud, Gašper Tkačik, Olivier Marre
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Retinal ganglion cell subtypes are traditionally thought to encode a single visual feature across the visual field to form a feature map. Here the authors show that fast OFF ganglion cells in fact respond to two visual features, either object positio
Externí odkaz:
https://doaj.org/article/38d2e261c11840d08ef8be2a12c55a69