Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Olivier Lucar"'
Autor:
Olivier Lucar, Bin Su, Valérie Potard, Assia Samri, Brigitte Autran, Christiane Moog, Patrice Debré, Vincent Vieillard
Publikováno v:
EBioMedicine, Vol 22, Iss C, Pp 122-132 (2017)
Antibodies (Abs) play a central role in human immunodeficiency virus (HIV) protection due to their multiple functional inhibitory activities. W614A-3S Abs recognize a specific form of a highly conserved motif of the gp41 envelope protein and can elic
Externí odkaz:
https://doaj.org/article/dd31f954b9dd444cbf678d85eb7d0e2d
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Despite efficient suppression of plasma viremia in people living with HIV (PLWH) on cART, evidence of HIV-induced immunosuppression remains, and normally benign and opportunistic pathogens become major sources of co-morbidities, including virus-induc
Externí odkaz:
https://doaj.org/article/d2b342c014014349afa1d7d4874c107e
Autor:
Karim Dorgham, Nicolas Pietrancosta, Amel Affoune, Olivier Lucar, Tahar Bouceba, Solenne Chardonnet, Cedric Pionneau, Christophe Piesse, Delphine Sterlin, Pablo Guardado-Calvo, Philippe Karoyan, Patrice Debré, Guy Gorochov, Vincent Vieillard
Publikováno v:
Journal of Immunology Research, Vol 2019 (2019)
The design of immunogens susceptible to elicit potent and broadly neutralizing antibodies against the human immunodeficiency virus type 1 (HIV-1) remains a veritable challenge in the course of vaccine development. Viral envelope proteins adopt differ
Externí odkaz:
https://doaj.org/article/f29c5a2d7dc149c0acec4b014d2a160a
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Viral infections trigger robust secretion of interferons and other antiviral cytokines by infected and bystander cells, which in turn can tune the immune response and may lead to viral clearance or immune suppression. However, aberrant or unrestricte
Externí odkaz:
https://doaj.org/article/ebca2f8f04764258aa166077bedb1d0b
Publikováno v:
Eur J Immunol
Cytokine-induced memory-like (CIML) NK cells are endowed with the capacity to mediate enhanced effector functions upon cytokine or activating receptor re-stimulation for several weeks following short-term pre-activation with IL-12, IL-15 and IL-18. P
Publikováno v:
Journal of Leukocyte Biology. 105:1253-1259
NK cells play a critical role in antiviral and antitumor responses. Although current NK cell immune therapies have focused primarily on cancer biology, many of these advances can be readily applied to target HIV/simian immunodeficiency virus (SIV)-in
Autor:
Marcus Altfeld, R. Keith Reeves, Kyle Kroll, George Tweet, Taylor Yoder, Sho K. Sugawara, Paul A. Goepfert, Haley L. Dugan, Scott Smith, Adam Grundhoff, Olivier Lucar, Stephanie Jost, Joshua Ghofrani, Alexandra Werner, Phillip J. Tomezsko, Michaela Müller-Trutwin, Rhianna Jones
For over a decade, multiple studies have disputed the notion of natural killer (NK) cells as purely innate lymphocytes by demonstrating that they are capable of putative antigen-specific immunological memory against multiple infectious agents includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50b311c059cd5b89758b793c7655ad3f
https://doi.org/10.1101/2020.11.09.374348
https://doi.org/10.1101/2020.11.09.374348
Publikováno v:
Journal of Virology. 93
Recently, we and others have shown that natural killer (NK) cells exhibit memory-like recall responses against cytomegalovirus (CMV) and human immunodeficiency/virus simian immunodeficiency virus (HIV/SIV) infections. Although the mechanism(s) have n
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology
Despite efficient suppression of plasma viremia in people living with HIV (PLWH) on cART, evidence of HIV-induced immunosuppression remains, and normally benign and opportunistic pathogens become major sources of co-morbidities, including virus-induc
Publikováno v:
Journal of virology. 93(16)
Recently, we and others have shown that natural killer (NK) cells exhibit memory-like recall responses against cytomegalovirus (CMV) and human immunodeficiency/virus simian immunodeficiency virus (HIV/SIV) infections. Although the mechanism(s) have n