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pro vyhledávání: '"Olivier Le Bussy"'
Autor:
Daphne Keulen, Erik van der Hagen, Geoffroy Geldhof, Olivier Le Bussy, Martin Pabst, Marcel Ottens
Publikováno v:
Biotechnology and Bioengineering
An optimal purification process for biopharmaceutical products is important to meet strict safety regulations, and for economic benefits. To find the global optimum, it is desirable to screen the overall design space. Advanced model-based approaches
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Publikováno v:
Biotechnology Journal
Mass-spectrometry-based proteomics is increasingly employed to monitor purification processes or to detect critical host cell proteins in the final drug substance. This approach is inherently unbiased and can be used to identify individual host cell
Externí odkaz:
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Publikováno v:
The Journal of biological chemistry. 271(39)
Chloride is the allosteric effector of vertebrate pancreatic and salivary alpha-amylases and of the bacterial alpha-amylase from Alteromonas haloplanctis. Activation experiments of A. haloplanctis alpha-amylase by several monovalent anions show that