Zobrazeno 1 - 10
of 263
pro vyhledávání: '"Olivier Laprévote"'
Autor:
Théodore Decaix, Romain Magny, Isabelle Gouin‐Thibaut, Xavier Delavenne, Patrick Mismetti, Joe‐Elie Salem, Céline Narjoz, Anne Blanchard, Marion Pépin, Nicolas Auzeil, Marie‐Anne Loriot, Olivier Laprévote
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 10, Pp 1935-1946 (2023)
Abstract P‐glycoprotein (P‐gp) is an efflux transporter involved in the bioavailability of many drugs currently on the market. P‐gp is responsible for several drug–drug interactions encountered in clinical practice leading to iatrogenic hospi
Externí odkaz:
https://doaj.org/article/c16a904f55da45c38e0c3e19ed9a03b4
Autor:
Vanessa Naffaa, Isabelle Hochar, Chéryane Lama, Romain Magny, Anne Regazzetti, Pierre Gressens, Olivier Laprévote, Nicolas Auzeil, Anne-Laure Schang
Publikováno v:
Molecules, Vol 27, Iss 7, p 2274 (2022)
In the central nervous system, the process of myelination involves oligodendrocytes that wrap myelin around axons. Myelin sheaths are mainly composed of lipids and ensure efficient conduction of action potentials. Oligodendrocyte differentiation is a
Externí odkaz:
https://doaj.org/article/fa470ee35c854a739cee01f4f7f3510a
Autor:
Takahisa Yamato, Olivier Laprévote
Publikováno v:
Biophysics and Physicobiology, Vol 16 (2019)
Normal mode analysis provides a powerful tool in biophysical computations. Particularly, we shed light on its application to protein properties because they directly lead to biological functions. As a result of normal mode analysis, the protein motio
Externí odkaz:
https://doaj.org/article/79d68dd915c840609ee3a7f9cc6c9bce
Autor:
Sonia Askri, Amal Dbeibia, Chadlia Mchiri, Sarra Boudriga, Michael Knorr, Emmanuel Roulland, Olivier Laprévote, Nathalie Saffon-Merceron, Rafik Gharbi
Publikováno v:
Applied Sciences, Vol 12, Iss 1, p 360 (2021)
Three-component cascade reactions of (E)-3-arylidene-1-methyl-pyrrolidine-2,5-diones, L-valine and various isatin derivatives are described. A series of 17 spiropyrrolidine derivatives with wide structural complexity and diversity have been thus obta
Externí odkaz:
https://doaj.org/article/170a3191340d4f7884703c8ea90869b8
Autor:
Elise Saunier, Samantha Antonio, Anne Regazzetti, Nicolas Auzeil, Olivier Laprévote, Jerry W. Shay, Xavier Coumoul, Robert Barouki, Chantal Benelli, Laurence Huc, Sylvie Bortoli
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Resveratrol (RES), a polyphenol found in natural foods, displays anti-oxidant, anti-inflammatory and anti-proliferative properties potentially beneficial in cancers, in particular in the prevention of tumor growth. However, the rapid metabol
Externí odkaz:
https://doaj.org/article/3a75a7d127634bdc9062881bbbb61ac9
Autor:
Romain Magny, Anne Regazzetti, Karima Kessal, Gregory Genta-Jouve, Christophe Baudouin, Stéphane Mélik-Parsadaniantz, Françoise Brignole-Baudouin, Olivier Laprévote, Nicolas Auzeil
Publikováno v:
Metabolites, Vol 10, Iss 6, p 225 (2020)
Annotation of lipids in untargeted lipidomic analysis remains challenging and a systematic approach needs to be developed to organize important datasets with the help of bioinformatic tools. For this purpose, we combined tandem mass spectrometry-base
Externí odkaz:
https://doaj.org/article/4b87e768058b43ebae05adad841862d5
Autor:
Axelle Aimond, Kevin Calabro, Coralie Audoin, Elodie Olivier, Mélody Dutot, Pauline Buron, Patrice Rat, Olivier Laprévote, Soizic Prado, Emmanuel Roulland, Olivier P. Thomas, Grégory Genta-Jouve
Publikováno v:
Molecules, Vol 25, Iss 3, p 589 (2020)
This paper reports the isolation and structural characterization of four new ent-kaurane derivatives from the Lamiaceae plant Sideritis hyssopifolia. Planar structures and relative configurations were determined using both mass spectrometry and nucle
Externí odkaz:
https://doaj.org/article/97b86647e139424487f973224340d0dd
Autor:
Sophie Ayciriex, Fathia Djelti, Sandro Alves, Anne Regazzetti, Mathieu Gaudin, Jennifer Varin, Dominique Langui, Ivan Bièche, Eloise Hudry, Delphine Dargère, Patrick Aubourg, Nicolas Auzeil, Olivier Laprévote, Nathalie Cartier
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Impairment in cholesterol metabolism is associated with many neurodegenerative disorders including Alzheimer's disease (AD). However, the lipid alterations underlying neurodegeneration and the connection between altered cholesterol levels and AD rema
Externí odkaz:
https://doaj.org/article/36701410ec094cada7a18c8bf864ef5d
Autor:
Maï Panchal, Mathieu Gaudin, Adina N. Lazar, Elisa Salvati, Isabelle Rivals, Sophie Ayciriex, Luce Dauphinot, Delphine Dargère, Nicolas Auzeil, Massimo Masserini, Olivier Laprévote, Charles Duyckaerts
Publikováno v:
Neurobiology of Disease, Vol 65, Iss , Pp 193-201 (2014)
The senile plaque is a hallmark lesion of Alzheimer disease (AD). We compared, without a priori, the lipidome of the senile plaques and of the adjacent plaque-free neuropil. The analysis by liquid chromatography coupled with electrospray ionization m
Externí odkaz:
https://doaj.org/article/1709aae4b57549bf871d64a866e44439
Autor:
Marc Brulet, Alexandre Seyer, Aleksander Edelman, Alain Brunelle, Janine Fritsch, Mario Ollero, Olivier Laprévote
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 10, Pp 3034-3045 (2010)
The cftr knockout mouse model of cystic fibrosis (CF) shows intestinal obstruction; malabsorption and inflammation; and a fatty acid imbalance in intestinal mucosa. We performed a lipid mapping of colon sections from CF and control (WT) mice by clust
Externí odkaz:
https://doaj.org/article/e715d82879064585a4703fee09b15ccf