Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Olivier Grémy"'
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Purpose: In cases of occupational accidents in nuclear facilities or subsequent to terrorist activities, the most likely routes of internal contamination with alpha-particle emitting actinides, such as plutonium (Pu) and americium (Am), are by inhala
Externí odkaz:
https://doaj.org/article/9a5203053129422693ef223c73e6e87c
Publikováno v:
Chemico-Biological Interactions. 378:110488
Publikováno v:
Health physics. 123(3)
An individual underwent an extensive diethylenetriaminepentaacetate (DTPA) chelation therapy that started several months after plutonium incorporation, most likely by inhalation of a soluble compound. After receiving multiple intravenous infusions of
Publikováno v:
Health Physics
In a worker who had internalized plutonium, most likely through inhalation of a somewhat soluble compound, an extensive diethylenetriaminepentaacetate (DTPA) treatment regimen was initiated several months after contamination. Numerous radiotoxicologi
Autor:
Olivier Grémy, Nina M. Griffiths, Solveig Bibard, Stephanie Lamart, Laurent Miccoli, Sophie Dubois, Anne Van der Meeren, Sylvie Coudert, Jaime F. Angulo, Ana Paula Serond
Publikováno v:
Journal of Radiological Protection. 39:707-738
Americium (Am) biodistribution data obtained after wound contamination in rats were analysed to evaluate and quantify the influence of different physicochemical forms of Am in the presence or absence of plutonium (Pu). The biodistribution data were i
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology
Frontiers in Pharmacology
Purpose: In cases of occupational accidents in nuclear facilities or subsequent to terrorist activities, the most likely routes of internal contamination with alpha-particle emitting actinides, such as plutonium (Pu) and americium (Am), are by inhala
Autor:
Olivier Grémy, Karine Devilliers, Pierre Laroche, Marie Mougin-Degraef, Marion Berdal, Laurent Miccoli
Publikováno v:
Radiation Research
Radiation Research, 2021, 195 (1), ⟨10.1667/RADE-20-00142.1⟩
Radiation Research, 2021, 195 (1), ⟨10.1667/RADE-20-00142.1⟩
International audience; Administration of diethylenetriaminepentaacetic acid (DTPA) is the treatment approach used to promote the decorporation of internalized plutonium. Here we evaluated the efficacy of PEGylated liposomes coated with DTPA, primari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f86ba19fc4084c0afcb7894adb24a1
https://www.hal.inserm.fr/inserm-03540754
https://www.hal.inserm.fr/inserm-03540754
Background: Internal contamination with plutonium is a potential hazard for workers handling this alpha-emitting transuranic element. The only medical approach available for reducing potential health effects is to promote plutonium excretion by chela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7f18b358112ddd3661283ff00fd287e
https://doi.org/10.21203/rs.3.rs-103959/v1
https://doi.org/10.21203/rs.3.rs-103959/v1
Autor:
Olivier Grémy, Laurent Miccoli, Sandra Bohand, Michel Chérel, Faustine Lelan, Marie Mougin-Degraef
Publikováno v:
Radiation Research
Radiation Research, 2018, 189 (5), pp.477-489. ⟨10.1667/RR14968.1⟩
Radiation Research, Radiation Research Society, 2018, 189 (5), pp.477-489. ⟨10.1667/RR14968.1⟩
Radiation Research, 2018, 189 (5), pp.477-489. ⟨10.1667/RR14968.1⟩
Radiation Research, Radiation Research Society, 2018, 189 (5), pp.477-489. ⟨10.1667/RR14968.1⟩
International audience; In this study, we assessed the efficacy of unilamellar 110-nm liposomes encapsulating the chelating agent diethylenetriaminepentaacetic acid (DTPA) in plutonium-exposed rats. Rats were contaminated by intravenous administratio
Publikováno v:
Radiation research. 192(6)
Occupational contamination is a potential health risk associated with plutonium inhalation. DTPA remains the chelating drug of choice to decorporate plutonium. In this study, plutonium was found to be more effectively removed from lungs by a single i