Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Olivier Gascuel"'
Publikováno v:
Methods in Ecology and Evolution, Vol 14, Iss 2, Pp 487-495 (2023)
Abstract Stochastic population dynamics simulations are essential for many ecological and epidemiological studies to generate time series and genealogies that capture the relatedness between individuals. Many software packages allow one to simulate p
Externí odkaz:
https://doaj.org/article/cec4128e27fd4e1c8f9b2cbfdd195060
Autor:
Pauline Trémeaux, Frédéric Lemoine, Adeline Mélard, Marine Gousset, Faroudy Boufassa, Sylvie Orr, Valérie Monceaux, Olivier Gascuel, Olivier Lambotte, Laurent Hocqueloux, Asier Saez-Cirion, Christine Rouzioux, Véronique Avettand-Fenoel
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT In the search for control of human immunodeficiency virus type 1 (HIV-1) infection without antiretroviral therapy, posttreatment controllers (PTCs) are models of HIV remission. To better understand their mechanisms of control, we characteriz
Externí odkaz:
https://doaj.org/article/8e62f5197b554293924fa6c48469dcf9
Publikováno v:
Viruses, Vol 15, Iss 6, p 1244 (2023)
A deeper understanding of HIV-1 transmission and drug resistance mechanisms can lead to improvements in current treatment policies. However, the rates at which HIV-1 drug resistance mutations (DRMs) are acquired and which transmitted DRMs persist are
Externí odkaz:
https://doaj.org/article/10ee6efadd47485e92a5535ad701aeb1
Autor:
Grigorii Sukhorukov, Maryam Khalili, Olivier Gascuel, Thierry Candresse, Armelle Marais-Colombel, Macha Nikolski
Publikováno v:
Frontiers in Bioinformatics, Vol 2 (2022)
High-throughput sequencing has provided the capacity of broad virus detection for both known and unknown viruses in a variety of hosts and habitats. It has been successfully applied for novel virus discovery in many agricultural crops, leading to the
Externí odkaz:
https://doaj.org/article/1ffd39107bc4412ba8aac50f49aa8e6f
Autor:
Mihaela Oprea, Elisabeth Njamkepo, Daniela Cristea, Anna Zhukova, Clifford G. Clark, Anatoly N. Kravetz, Elena Monakhova, Adriana S. Ciontea, Radu Cojocaru, Jean Rauzier, Maria Damian, Olivier Gascuel, Marie-Laure Quilici, François-Xavier Weill
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Since 1970, several cholera outbreaks caused by the “seventh pandemic” (7PET) lineage have been reported in Europe. Here, the authors demonstrate that the outbreaks were caused by repeated introductions of 7PET into Europe, rather than local envi
Externí odkaz:
https://doaj.org/article/8d7c3509d653499ca7544813f3214efb
Autor:
Anna Zhukova, Jakub Voznica, Miraine Dávila Felipe, Thu-Hien To, Lissette Pérez, Yenisleidys Martínez, Yanet Pintos, Melissa Méndez, Olivier Gascuel, Vivian Kouri
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010224 (2022)
[This corrects the article DOI: 10.1371/journal.ppat.1009786.].
Externí odkaz:
https://doaj.org/article/6db0ed9ca3a8472183038125c9f56a9c
Autor:
Luc Blassel, Anna Tostevin, Christian Julian Villabona-Arenas, Martine Peeters, Stéphane Hué, Olivier Gascuel, UK HIV Drug Resistance Database
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 8, p e1008873 (2021)
Drug resistance mutations (DRMs) appear in HIV under treatment pressure. DRMs are commonly transmitted to naive patients. The standard approach to reveal new DRMs is to test for significant frequency differences of mutations between treated and naive
Externí odkaz:
https://doaj.org/article/f24dab1ce4724b9696dc6e25ea878cb0
Autor:
Anna Zhukova, Jakub Voznica, Miraine Dávila Felipe, Thu-Hien To, Lissette Pérez, Yenisleidys Martínez, Yanet Pintos, Melissa Méndez, Olivier Gascuel, Vivian Kouri
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009786 (2021)
CRF19 is a recombinant form of HIV-1 subtypes D, A1 and G, which was first sampled in Cuba in 1999, but was already present there in 1980s. CRF19 was reported almost uniquely in Cuba, where it accounts for ∼25% of new HIV-positive patients and caus
Externí odkaz:
https://doaj.org/article/f82177b4d46c46c9b8061baf923cded8
Publikováno v:
BMC Evolutionary Biology, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background Ancestral character states computed from the combination of phylogenetic trees with extrinsic traits are used to decipher evolutionary scenarios in various research fields such as phylogeography, epidemiology, and ecology. Despite
Externí odkaz:
https://doaj.org/article/9199afa4c3584a8ebe44d40b27a75485
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 1, p e1005889 (2018)
Comparing and aligning protein sequences is an essential task in bioinformatics. More specifically, local alignment tools like BLAST are widely used for identifying conserved protein sub-sequences, which likely correspond to protein domains or functi
Externí odkaz:
https://doaj.org/article/ea0053acea6e4d349465a49d6da1f440