Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Olivier Diaz"'
Autor:
Olivier Diaz, Pierre-Olivier Vidalain, Christophe Ramière, Vincent Lotteau, Laure Perrin-Cocon
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Hepatitis B, C and D viruses (HBV, HCV, HDV, respectively) specifically infect human hepatocytes and often establish chronic viral infections of the liver, thus escaping antiviral immunity for years. Like other viruses, hepatitis viruses rely on the
Externí odkaz:
https://doaj.org/article/0f34342b50b44a14b2f2c11fb18ee0ac
Autor:
Laure Perrin-Cocon, Pierre-Olivier Vidalain, Clémence Jacquemin, Anne Aublin-Gex, Keedrian Olmstead, Baptiste Panthu, Gilles Jeans Philippe Rautureau, Patrice André, Piotr Nyczka, Marc-Thorsten Hütt, Nivea Amoedo, Rodrigue Rossignol, Fabian Volker Filipp, Vincent Lotteau, Olivier Diaz
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Many cancers fuel their rapid growth by replacing glucokinase with its higher affinity isoenzyme, hexokinase 2 (HK2), making HK2 an attractive drug target. In this study, Perrin-Cocon and Vidalain et al. use CRISPR/Cas-9 gene editing to reverse this
Externí odkaz:
https://doaj.org/article/a519b0af2fba49868394944910f843d0
Autor:
Laure Perrin-Cocon, Olivier Diaz, Clémence Jacquemin, Valentine Barthel, Eva Ogire, Christophe Ramière, Patrice André, Vincent Lotteau, Pierre-Olivier Vidalain
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-15 (2020)
Abstract In less than 20 years, three deadly coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-2, have emerged in human population causing hundreds to hundreds of thousands of deaths. Other coronaviruses are causing epizootic representing a significant
Externí odkaz:
https://doaj.org/article/d2c409fff17147a89746b9beca0c2926
Autor:
Laure Perrin-Cocon, Cindy Kundlacz, Clémence Jacquemin, Xavier Hanoulle, Anne Aublin-Gex, Marianne Figl, Jeremy Manteca, Patrice André, Pierre-Olivier Vidalain, Vincent Lotteau, Olivier Diaz
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 919 (2022)
Hepatitis C virus (HCV) relies on cellular lipid metabolism for its replication, and actively modulates lipogenesis and lipid trafficking in infected hepatocytes. This translates into an intracellular accumulation of triglycerides leading to liver st
Externí odkaz:
https://doaj.org/article/b441152eacc446fab2beaa32b55e1d80
Autor:
Eva Ogire, Olivier Diaz, Pierre-Olivier Vidalain, Vincent Lotteau, Philippe Desprès, Marjolaine Roche
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1951 (2021)
La Reunion island in the South West Indian Ocean is now endemic for dengue following the introduction of dengue virus serotype 2 (DENV-2) cosmopolitan-I genotype in 2017. DENV-2 infection causes a wide spectrum of clinical manifestations ranging from
Externí odkaz:
https://doaj.org/article/a3114493326b4682a5a99713aa2356d0
Autor:
Elena L. Enache, Anca Sin, Ligia Bancu, Christophe Ramière, Olivier Diaz, Patrice André, Liviu S. Enache
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 9, Pp 22223-22242 (2015)
Chronic hepatitis C (CHC) is a major burden for public health worldwide. Although newer direct-acting antivirals show good efficacy, their cost precludes their wide adoption in resource-limited regions. Thus, strategies are being developed to help id
Externí odkaz:
https://doaj.org/article/b61f8699c5e6411f9b45079d413c1cbb
Autor:
Liviu S. Enache, Elena L. Enache, Christophe Ramière, Olivier Diaz, Ligia Bancu, Anca Sin, Patrice André
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 10, Pp 17644-17666 (2014)
Liver disease is a major cause of morbidity and mortality worldwide. As in other fields of medicine, there is a stringent need for non-invasive markers to improve patient diagnostics, monitoring and prognostic ability in liver pathology. Cell-free ci
Externí odkaz:
https://doaj.org/article/50028a48779141ba89f79ffb181d51da
Autor:
Isabel Pombo Grégoire, Clémence Richetta, Laurène Meyniel-Schicklin, Sophie Borel, Fabrine Pradezynski, Olivier Diaz, Alexandre Deloire, Olga Azocar, Joël Baguet, Marc Le Breton, Philippe E Mangeot, Vincent Navratil, Pierre-Emmanuel Joubert, Monique Flacher, Pierre-Olivier Vidalain, Patrice André, Vincent Lotteau, Martine Biard-Piechaczyk, Chantal Rabourdin-Combe, Mathias Faure
Publikováno v:
PLoS Pathogens, Vol 7, Iss 12, p e1002422 (2011)
Autophagy is a conserved degradative pathway used as a host defense mechanism against intracellular pathogens. However, several viruses can evade or subvert autophagy to insure their own replication. Nevertheless, the molecular details of viral inter
Externí odkaz:
https://doaj.org/article/f522e87acc8f40f39a32b6dfbd15fc1a
Autor:
Vinca Icard, Olivier Diaz, Caroline Scholtes, Laure Perrin-Cocon, Christophe Ramière, Ralf Bartenschlager, Francois Penin, Vincent Lotteau, Patrice André
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4233 (2009)
The density of circulating hepatitis C virus (HCV) particles in the blood of chronically infected patients is very heterogeneous. The very low density of some particles has been attributed to an association of the virus with apolipoprotein B (apoB) p
Externí odkaz:
https://doaj.org/article/137359f19e2c4e439a6b087bf4e20faa
Autor:
Laure Perrin-Cocon, Sophie Agaugué, Olivier Diaz, Béatrice Vanbervliet, Sandra Dollet, Aurélie Guironnet-Paquet, Patrice André, Vincent Lotteau
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2260 (2008)
BACKGROUND: Lack of protective antibodies and inefficient cytotoxic responses are characteristics of chronic hepatitis C infection. A defect in dendritic cell (DC) function has thus been suspected, but this remains a controversial issue. METHODS AND
Externí odkaz:
https://doaj.org/article/207b3afe95d145909fb5ac273915fd0b