Výsledky vyhledávání - "Olivier Brégerie"

Liver tetraploidization is controlled by a new process of incomplete cytokinesis

Autor: Olivier Brégerie, Germain Margall-Ducos, Séverine Celton-Morizur, Dominique Couton, Chantal Desdouets

Publikováno v: Journal of cell science. 120(Pt 20)

Cytokinesis is precisely controlled in both time and space to ensure equal distribution of the genetic material between daughter cells. Incomplete cytokinesis can be associated with developmental or pathological cell division programs leading to tetr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a20c378cad098637dc19e8a36136216
https://pubmed.ncbi.nlm.nih.gov/17895361

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The intraflagellar transport component IFT88/polaris is a centrosomal protein regulating G1-S transition in non-ciliated cells

Autor: Christian Bréchot, Olivier Brégerie, Aude Robert, Claude Celati, Jacques-Emmanuel Guidotti, Germain Margall-Ducos, Chantal Desdouets

Publikováno v: Journal of cell science. 120(Pt 4)

Loss of normal primary cilia function in mammals is linked to proliferative diseases, such as polycystic kidney disease, suggesting a regulatory relationship between cilia and cell cycle. The primary cilium expressed by most mammalian cells is nuclea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365e50a921d20f36c8c39153493c86a9
https://pubmed.ncbi.nlm.nih.gov/17264151

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Conserved balance of hepatocyte nuclear DNA content in mononuclear and binuclear hepatocyte populations during the course of chronic viral hepatitis

Autor: Takashi Kumada, Olivier Brégerie, Hidenori Toyoda, Christian Bréchot, Chantal Desdouets

AIM: To analyze the percentages of hepatocytes with increased nuclear DNA content, i.e., tetraploid (4n) and octoploid (8n) nuclei, and then compared mononuclear and binuclear hepatocyte populations:METHODS: The percentages of mononuclear diploid(2n)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b9ec131a74b17e5e10ad407e1770a3
https://europepmc.org/articles/PMC4125644/

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Changes to hepatocyte ploidy and binuclearity profiles during human chronic viral hepatitis

Autor: C Desdouets, C. Brechot, G Pivert, Olivier Brégerie, Bertrand Nalpas, H Toyoda, A Vallet

Background and aim: The importance of the hepatocyte ploidisation pattern to the control of cell proliferation and differentiation has been well established. However, there are no data that have characterised hepatocyte ploidy at various stages of ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fabbd8b2e9edf58debd24a909cf6077e
https://europepmc.org/articles/PMC1774850/

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Liver cell polyploidization : a pivotal role for binuclear hepatocytes

Autor: Aude Robert, Olivier Brégerie, Chantal Desdouets, Pascale Debey, Christian Bréchot, Jacques-Emanuelle Guidotti

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2003, 278 (21), pp.19095-19101
Journal of Biological Chemistry 21 (278), 19095-19101. (2003)

Polyploidy is a general physiological process indicative of terminal differentiation. During liver growth, this process generates the appearance of tetraploid (4n) and octoploid (8n) hepatocytes with one or two nuclei. The onset of polyploidy in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c77dd38d3f8b78f8d45dab4c8739a8
https://hal.inrae.fr/hal-02679584/document

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542 INTERNAL RADIOTHERAPY OF LIVER CANCER USING RAT HEPATOCARCINOMA-INTESTINE-PANCREAS GENE AS A LIVER TUMOR-SPECIFIC PROMOTER

Autor: Julie Herve, Bertrand Tavitian, Jamila Faivre, Didier Samuel, B. Liu, Michèle Longuet, Paul Calès, Yannick Valogne, C. Brechot, Jérôme Roux, Olivier Brégerie, Jérôme Clerc, Catherine Guettier, A. Sa Cunha, Raphaël Boisgard

Publikováno v: Journal of Hepatology. 48:S203-S204

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e0db66cb6cc51e41559849e2151832b6
https://doi.org/10.1016/s0168-8278(08)60544-9

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Internal radiotherapy of liver cancer with rat Hepatocarcinoma-Intestine-Pancreas gene as a liver tumor-specific promoter

Autor: Bertrand Tavitian, Jamila Faivre, Jérôme Roux, Catherine Guettier, Olivier Brégerie, Jérôme Clerc, B. Liu, Antonio Sa Cunha, Michèle Longuet, Didier Samuel, Paul Calès, Yannick Valogne, Julie Herve, Raphaël Boisgard, Christian Bréchot

Publikováno v: Human Gene Therapy
Human Gene Therapy, Mary Ann Liebert, 2008, 19 (9), pp.915-926. ⟨10.1089/hum.2007.153⟩
Human Gene Therapy, 2008, 19 (9), pp.915-926. ⟨10.1089/hum.2007.153⟩

International audience; The hepatocarcinoma-intestine-pancreas (HIP) gene, also called pancreatitis-associated protein-1 (PAP1) or Reg IIIα, is activated in most human hepatocellular carcinomas (HCCs) but not in normal liver, which suggests that HIP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b0cf88b3352e6f00665c56931a3394
https://doi.org/10.1089/hgt.2007.153

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