Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Olivier Boyé"'
Autor:
Catalina Abad, Iago Pinal-Fernandez, Clement Guillou, Gwladys Bourdenet, Laurent Drouot, Pascal Cosette, Margherita Giannini, Lea Debrut, Laetitia Jean, Sophie Bernard, Damien Genty, Rachid Zoubairi, Isabelle Remy-Jouet, Bernard Geny, Christian Boitard, Andrew Mammen, Alain Meyer, Olivier Boyer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Idiopathic inflammatory myopathies (IIMs) are severe autoimmune diseases with poorly understood pathogenesis and unmet medical needs. Here, we examine the role of interferon γ (IFNγ) using NOD female mice deficient in the inducible T cell
Externí odkaz:
https://doaj.org/article/5feb3ed90f3c49a49fed689d6693d55c
Autor:
Souleymane Abdoul-Azize, Rihab Hami, Gaetan Riou, Céline Derambure, Camille Charbonnier, Jean-Pierre Vannier, Monica L. Guzman, Pascale Schneider, Olivier Boyer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Glucocorticoid (GC) resistance in childhood relapsed B-cell acute lymphoblastic leukemia (B-ALL) represents an important challenge. Despite decades of clinical use, the mechanisms underlying resistance remain poorly understood. Here, we repo
Externí odkaz:
https://doaj.org/article/31c263362b6849da9206a6c385cee2f8
Publikováno v:
RMD Open, Vol 10, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/297d50d8eee6411481e3398e10161a07
Autor:
Mayumi Sugita, Takahiro Yamazaki, Mohammad Alhomoud, Jérémie Martinet, Jean-Baptiste Latouche, Encouse Golden, Olivier Boyer, Koen Van Besien, Silvia C. Formenti, Lorenzo Galluzzi, Monica L. Guzman
Publikováno v:
Cell Death and Disease, Vol 14, Iss 5, Pp 1-8 (2023)
Abstract Autologous T cells engineered to express a chimeric antigen receptor (CAR) specific for CD19 are approved for the treatment of various CD19+ hematological malignancies. While CAR T cells induce objective responses in a majority of patients,
Externí odkaz:
https://doaj.org/article/aa1f1d202091484a98064e5028973f74
Publikováno v:
Antibodies, Vol 13, Iss 1, p 12 (2024)
Immune-mediated necrotizing myopathy (IMNM) is a rare and severe disease that corresponds to a specific entity of idiopathic inflammatory myopathy. Patients with IMNM suffer from proximal muscle weakness, and present high levels of creatine kinase an
Externí odkaz:
https://doaj.org/article/9870d576963d4d13ab17b99b655d18b9
Autor:
Helena Costa-Verdera, Fanny Collaud, Christopher R. Riling, Pauline Sellier, Jayme M. L. Nordin, G. Michael Preston, Umut Cagin, Julien Fabregue, Simon Barral, Maryse Moya-Nilges, Jacomina Krijnse-Locker, Laetitia van Wittenberghe, Natalie Daniele, Bernard Gjata, Jeremie Cosette, Catalina Abad, Marcelo Simon-Sola, Severine Charles, Mathew Li, Marco Crosariol, Tom Antrilli, William J. Quinn, David A. Gross, Olivier Boyer, Xavier M. Anguela, Sean M. Armour, Pasqualina Colella, Giuseppe Ronzitti, Federico Mingozzi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Pompe disease is currently treated with enzyme replacement therapy (ERT) with recombinant human acid alpha-glucosidase (GAA). Here, the authors show hepatic-directed gene therapy with AAV vectors enhances GAA bioavailability compared with ERT, result
Externí odkaz:
https://doaj.org/article/ecdd7a66d5fe4b0e825ff6e616f835cf
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 33:293-299
14C-Chloroacetates of 2-demethylthiocolchicine 7 (specific activity 55.0 mCi/mmol, radiochemical yield 26.1%), and of 3-demethylthiocolchicine 8 (specific activity 55.0 mCi/mmol, radiochemical yield 5.7%) were synthesized and found to covalently bind
Autor:
Marie-Laure Golinski, Alexandre Lemieux, Maud Maho-Vaillant, Marion Barray, Laurent Drouot, Damien Schapman, Marie Petit, Michael Hertl, Olivier Boyer, Sébastien Calbo, Pascal Joly, Vivien Hébert
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionWe studied the distribution and in vitro pathogenicity of anti-DSG3 IgG subclasses during the course of pemphigus vulgaris (PV).MethodsWe longitudinally studied the distribution of anti-DSG3 IgG subclasses (before versus after treatment)
Externí odkaz:
https://doaj.org/article/1b461e2b49d84990a506c24699d0ead2
Autor:
Dominique Bertrand, MD, Mouad Hamzaoui, MD, PhD, Laurent Drouot, PhD, Julie Lamulle, MA, Mélanie Hanoy, MD, Stéphane Edet, MD, Charlotte Laurent, MD, Ludivine Lebourg, MD, Isabelle Etienne, MD, Mathilde Lemoine, MD, Frank Le Roy, MD, Dorian Nezam, MD, Eleusis Mauger, MD, Olivier Boyer, MD, PhD, Dominique Guerrot, MD, PhD, Sophie Candon, MD, PhD
Publikováno v:
Transplantation Direct, Vol 7, Iss 12, p e792 (2021)
Background. Kidney transplantation and dialysis are two major risk factors for severe forms of coronavirus disease 2019 (COVID-19). The dynamics of the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in this population
Externí odkaz:
https://doaj.org/article/9036a2c630314485b4caca66a6375f22
Autor:
Pauline Brevet, Claire Lattard, Clément Guillou, Pascal Rottenberg, Patrice Fardellone, Xavier Le-Loët, Thierry Lequerré, Pascal Cosette, Olivier Boyer, Manuel Fréret, Olivier Vittecoq
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
To identify the targets recognized by anti-carbamylated protein antibodies (anti-CarP) in patients with early Rheumatoid Arthritis (RA), to study the cross-reactivity between anti-CarP and anti-citrullinated protein antibodies (ACPA) and to evaluate
Externí odkaz:
https://doaj.org/article/5c9d1f55529b4c27b88f502d1ad60f99