Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Olivier Bornert"'
Autor:
Daniel Kruppa, Florian Peters, Olivier Bornert, Mareike D. Maler, Stefan F. Martin, Christoph Becker-Pauly, Alexander Nyström
Publikováno v:
Matrix Biology Plus, Vol 11, Iss , Pp 100065- (2021)
Astacin-like proteinases (ALPs) are regulators of tissue and extracellular matrix (ECM) homeostasis. They convey this property through their ability to convert ECM protein pro-forms to functional mature proteins and by regulating the bioavailability
Externí odkaz:
https://doaj.org/article/bd9e3c62396f4563800b90d5fa038a34
Autor:
Olivier Bornert, Thomas Kocher, Christine Gretzmeier, Bernadette Liemberger, Stefan Hainzl, Ulrich Koller, Alexander Nyström
Publikováno v:
Matrix Biology Plus, Vol 4, Iss , Pp - (2019)
High conservation of extracellular matrix proteins often makes the generation of potent species-specific antibodies challenging. For collagen VII there is a particular preclinical interest in the ability to discriminate between human and murine colla
Externí odkaz:
https://doaj.org/article/c74b3b1c48774ab8bbe95bcf351ff6cc
Autor:
Randi Westh Hansen, Xiaole Wang, Agnieszka Golab, Olivier Bornert, Christine Oswald, Renaud Wagner, Karen Laurence Martinez
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0150658 (2016)
Long-term functional stability of isolated membrane proteins is crucial for many in vitro applications used to elucidate molecular mechanisms, and used for drug screening platforms in modern pharmaceutical industry. Compared to soluble proteins, the
Externí odkaz:
https://doaj.org/article/a5c92ce151e7486cbfce46a337242bcf
Autor:
Jeroen Bremer, Olivier Bornert, Alexander Nyström, Antoni Gostynski, Marcel F Jonkman, Annemieke Aartsma-Rus, Peter C van den Akker, Anna MG Pasmooij
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
The “generalized severe” form of recessive dystrophic epidermolysis bullosa (RDEB-gen sev) is caused by bi-allelic null mutations in COL7A1, encoding type VII collagen. The absence of type VII collagen leads to blistering of the skin and mucous m
Externí odkaz:
https://doaj.org/article/fb9cc181ecc84470ac0118eea81be9c1
Autor:
Olivier Bornert, Thor C Møller, Julien Boeuf, Marie-Pierre Candusso, Renaud Wagner, Karen L Martinez, Frederic Simonin
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56336 (2013)
GPCR desensitization and down-regulation are considered key molecular events underlying the development of tolerance in vivo. Among the many regulatory proteins that are involved in these complex processes, GASP-1 have been shown to participate to th
Externí odkaz:
https://doaj.org/article/80786f0b2ba24a03ad678b2d0d34b153
Autor:
Gabrielle Zeder-Lutz, Olivier Bornert, Rosine Fellmann-Clauss, Adeline Knittel-Obrecht, Thibaud Tranchant, Sarah Bouteben, Juliette Kaeffer, Raphaëlle Quillet, Pascal Villa, Renaud Wagner, Sandra Lecat, Frédéric Simonin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a4d470d7b843daa73def884c675ec9
https://linkinghub.elsevier.com/retrieve/pii/S0003269723000271
https://linkinghub.elsevier.com/retrieve/pii/S0003269723000271
Autor:
Verena Wally, Douglas R. Keene, M. Peter Marinkovich, Sara F. Tufa, Eva M. Murauer, Elisabeth M. Haisma, Alexander Nyström, Ulrich Koller, Dimitra Kiritsi, Pauline Nauroy, Marieke Hogervorst, Olivier Bornert, Stefan Hainzl, Gerard Platenburg, Ingrid Hausser, Tita Ritsema, Ioannis Athanasiou, Jim Swildens, Johannes Bischof
Publikováno v:
The Journal of investigative dermatology. 141(4)
Dystrophic epidermolysis bullosa (DEB) is a blistering skin disease caused by mutations in the gene COL7A1 encoding collagen VII. DEB can be inherited as recessive DEB (RDEB) or dominant DEB (DDEB) and is associated with a high wound burden. Perpetua
Autor:
Ingrid Hausser, Nadja Chmel, Jürgen Kohlhase, Cristina Has, Wiktor Borozkin, Olivier Bornert, Alexander Nyström, G. Grüninger
Publikováno v:
Journal of Investigative Dermatology. 138:987-991
Autor:
Mareike D. Maler, Daniel Kruppa, Olivier Bornert, Stefan F. Martin, Florian Peters, Alexander Nyström, Christoph Becker-Pauly
Publikováno v:
Matrix Biology Plus
Matrix Biology Plus, Vol 11, Iss, Pp 100065-(2021)
Matrix Biology Plus, Vol 11, Iss, Pp 100065-(2021)
Highlights • Meprins subtly support epidermal and dermal skin wound healing. • Loss of both meprins reduces re-epithelialization and wound macrophage abundance. • Meprin α is a physiological maturing proteinase of collagen VII. • Meprins are
Autor:
Olivier, Bornert, Alexander, Nyström
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1944
The size and relatively high GC content of cDNAs are challenges for efficient targeted engineering of large collagens. There are both basic biological and therapeutic interests in the ability to modify collagens, as this would allow for studies preci