Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Olivier A. Harari"'
Autor:
Leighann Litcher-Kelly, Ahmet Ozen, Sarah Ollis, Hagit Baris Feldman, Andrew Yaworsky, Paolo Medrano, Voranush Chongsrisawa, Taylor Brackin, Lorah Perlee, Marisa Walker, Sharanya Pradeep, Michael J. Lenardo, Olivier A. Harari, Jessica J. Jalbert
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Background CD55 deficiency with hyper-activation of complement, angiopathic thrombosis, and protein-losing enteropathy (CHAPLE) disease is ultra-rare (
Externí odkaz:
https://doaj.org/article/f82a2fd52091428c9e80233cbb076e5b
Autor:
Olivier A. Harari, James K. Liao
Publikováno v:
Annals of the New York Academy of Sciences. 1207:32-40
Acute cerebral ischemia elicits an innate immune response that leads to a cascade of events that culminates in necrotic death of neurons and injury to their supportive structures in the neurovascular unit. Indeed, clinical studies have shown a close
Autor:
Motoi Ohba, Joseph J. Boyle, Dorian O. Haskard, Olivier A. Harari, Justin C. Mason, Elaine A. Lidington, Allen M. Samarel, Mahrokh Nohadani, R. Steinberg
Publikováno v:
Journal of Biological Chemistry. 282:32288-32297
Endothelial cell apoptosis is associated with vascular injury and predisposes to atherogenesis. Endothelial cells express anti-apoptotic genes including Bcl-2, Bcl-XL and survivin, which also contribute to angiogenesis and vascular remodeling. We rep
Publikováno v:
Circulation Research. 98:1134-1140
Mammalian cells respond to bacterial lipopolysaccharide (LPS) through a cognate receptor: Toll-like receptor 4 (TLR4). The signaling pathways, which link TLR4 to the proinflammatory transcription factor nuclear factor κB (NF-κB), occur through the
Publikováno v:
The Journal of Immunology. 163:3993-4000
Dysfunctional leukocyte-endothelial interactions are thought to play a key role in systemic lupus erythematosus pathogenesis. We questioned the importance of TNF-α and IL-1 for endothelial activation in MRL/lpr lupus-prone mice. Endothelial ICAM-1 a
Publikováno v:
The Journal of Immunology. 162:1648-1655
We have studied vascular endothelial activation and increased expression of ICAM-1 and VCAM-1 at the onset of the elicitation phase of oxazolone contact hypersensitivity in mice. By measuring the local uptake of i.v. administered radiolabeled anti-IC
Autor:
Alejandro Recio-Mayoral, Juan C. Kaski, Michael B. Rubens, Paolo G. Camici, Olivier A. Harari, Justin C. Mason
Publikováno v:
European heart journal. 30(15)
Aims To demonstrate that exposure to chronic inflammation results in coronary microvascular dysfunction (CMD). Methods and results Using positron emission tomography, resting and hyperaemic (adenosine, 140 µg/kg/min) myocardial blood flow (MBF) was
Autor:
Alejandro Recio-Mayoral, Justin C Mason, Juan C Kaski, Michael B Rubens, Olivier A Harari, Paolo G Camici
Publikováno v:
Circulation. 118
Premature coronary atherosclerosis, which is actually seen as an active inflammatory process, is an established complication of systemic autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). We hypothesized tha
Publikováno v:
Nuclear medicine communications. 29(9)
Autor:
James K. Liao, Olivier A. Harari
Publikováno v:
Current pharmaceutical design. 10(8)
MHC class II molecules are expressed on the surface of antigen presenting cells and are loaded with peptides processed from the phagosomal compartment of these cells. Such complexes interact with the CD4 positive T lymphocyte receptor for antigen and