Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Olivier A, Bernard"'
Autor:
Alexandre Fagnan, Zakia Aid, Marie Baille, Aneta Drakul, Elie Robert, Cécile K. Lopez, Cécile Thirant, Yann Lecluse, Julie Rivière, Cathy Ignacimouttou, Silvia Salmoiraghi, Eduardo Anguita, Audrey Naimo, Christophe Marzac, Françoise Pflumio, Sébastien Malinge, Christian Wichmann, Yun Huang, Camille Lobry, Julie Chaumeil, Eric Soler, Jean‐Pierre Bourquin, Claus Nerlov, Olivier A. Bernard, Juerg Schwaller, Thomas Mercher
Publikováno v:
HemaSphere, Vol 8, Iss 6, Pp n/a-n/a (2024)
Abstract Transcriptional cofactors of the ETO family are recurrent fusion partners in acute leukemia. We characterized the ETO2 regulome by integrating transcriptomic and chromatin binding analyses in human erythroleukemia xenografts and controlled E
Externí odkaz:
https://doaj.org/article/03efbfad1704429ab5fd121446f5b220
Autor:
Elodie Pronier, Aygun Imanci, Dorothée Selimoglu-Buet, Bouchra Badaoui, Raphael Itzykson, Thierry Roger, Chloé Jego, Audrey Naimo, Maëla Francillette, Marie Breckler, Orianne Wagner-Ballon, Maria E. Figueroa, Marine Aglave, Daniel Gautheret, Françoise Porteu, Olivier A. Bernard, William Vainchenker, François Delhommeau, Eric Solary, Nathalie M. Droin
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
To improve our understanding of the pathological role of TET2 mutations, Pronier, Imanci et al. use mice and human cells to show that TET2 downregulation promotes the production of macrophage migration inhibitory factor (MIF). In addition they show t
Externí odkaz:
https://doaj.org/article/4004d3ab528c41bca20e05648bffe239
Autor:
Riccardo Rigo, Rabie Chelbi, Julie Agopian, Sebastien Letard, Aurélien Griffon, Hussein Ghamlouch, Julien Vernerey, Vasileios Ladopoulos, Edwige Voisset, Paulo De Sepulveda, Geoffrey Guittard, Jacques A. Nunès, Ghislain Bidaut, Berthold Göttgens, Michael Weber, Olivier A. Bernard, Patrice Dubreuil, Erinn Soucie
Publikováno v:
JCI Insight, Vol 7, Iss 7 (2022)
Mutation of the TET2 DNA-hydroxymethylase has been associated with a number of immune pathologies. The disparity in phenotype and clinical presentation among these pathologies leads to questions regarding the role of TET2 mutation in promoting diseas
Externí odkaz:
https://doaj.org/article/4730970c79894bdda7977a2e88bc7e6f
Autor:
Fotini Kostopoulou, Clementine Gabillaud, Elise Chapiro, Beatrice Grange, Julie Tran, Simon Bouzy, Michael Degaud, Hussein Ghamlouch, Magali Le Garff‐Tavernier, Karim Maloum, Sylvain Choquet, Veronique Leblond, Jean Gabarre, Anne Lavaud, Veronique Morel, Damien Roos‐Weil, Madalina Uzunov, Romain Guieze, Olivier A. Bernard, Santos A. Susin, Olivier Tournilhac, Florence Nguyen‐Khac, the French Innovative Leukemia Organization (FILO) group
Publikováno v:
Cancer Medicine, Vol 8, Iss 6, Pp 3131-3141 (2019)
Abstract The different types of drug resistance encountered in chronic lymphocytic leukemia (CLL) cannot be fully accounted for by the 17p deletion (and/or TP53 mutation), a complex karyotype (CK), immunoglobulin heavy‐chain variable region genes (
Externí odkaz:
https://doaj.org/article/7d10de105bfe4bc180f4ac188592025d
Autor:
Dorothée Selimoglu-Buet, Julie Rivière, Hussein Ghamlouch, Laura Bencheikh, Catherine Lacout, Margot Morabito, M’boyba Diop, Guillaume Meurice, Marie Breckler, Aurélie Chauveau, Camille Debord, Franck Debeurme, Raphael Itzykson, Nicolas Chapuis, Christophe Willekens, Orianne Wagner-Ballon, Olivier A. Bernard, Nathalie Droin, Eric Solary
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
A decrease in the fraction of non-classical monocytes is a hallmark of chronic myelomonocytic leukaemia. Taking advantage of this abnormal situation, the authors identify a mechanistic link between miR-150 and TET3 as being involved in monocyte subse
Externí odkaz:
https://doaj.org/article/5d55187610e84c0189ca6173abd8c67a
Autor:
Florence Nguyen-Khac, Simon Bouzy, Damien Roos-Weil, Clotilde Bravetti, Agathe Maillon, M’boyba Diop, Cécile Doualle, Nathalie Droin, Olivier A. Bernard, Elise Chapiro
Publikováno v:
HemaSphere, Vol 5, Iss 5, p e563 (2021)
Externí odkaz:
https://doaj.org/article/269a6ee0258648f194be8c6d70604418
Autor:
Jean‐Marie Michot, Cyril Quivoron, Clémentine Sarkozy, Alina Danu, Julien Lazarovici, Khalil Saleh, Yolla El‐Dakdouki, Vincent Goldschmidt, Camille Bigenwald, Matteo Dragani, Rastislav Bahleda, Capucine Baldini, Julia Arfi‐Rouche, Patricia Martin‐Romano, Lambros Tselikas, Anas Gazzah, Antoine Hollebecque, Ludovic Lacroix, David Ghez, Veronique Vergé, Christophe Marzac, Sophie Cotteret, Wassila Rahali, Jean‐Charles Soria, Christophe Massard, Olivier A. Bernard, Peggy Dartigues, Valérie Camara‐Clayette, Vincent Ribrag
Publikováno v:
American Journal of Hematology. 98:645-657
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83c09f85453cac881c334c43ddbe2644
https://doi.org/10.1002/ajh.26835
https://doi.org/10.1002/ajh.26835
Autor:
Paola Rivera-Munoz, Anouchka P. Laurent, Aurelie Siret, Cecile K. Lopez, Cathy Ignacimouttou, Melanie G. Cornejo, Olivia Bawa, Philippe Rameau, Olivier A. Bernard, Philippe Dessen, Gary D. Gilliland, Thomas Mercher, Sébastien Malinge
Publikováno v:
Blood Advances, Vol 2, Iss 13, Pp 1616-1627 (2018)
Abstract: JAK3-activating mutations are commonly seen in chronic or acute hematologic malignancies affecting the myeloid, megakaryocytic, lymphoid, and natural killer (NK) cell compartment. Overexpression models of mutant JAK3 or pharmacologic inhibi
Externí odkaz:
https://doaj.org/article/fa84d1f08a0b40b5b6c7e41936caf131
Autor:
Enguerran Mouly, Hussein Ghamlouch, Veronique Della-Valle, Laurianne Scourzic, Cyril Quivoron, Damien Roos-Weil, Patrycja Pawlikowska, Véronique Saada, M'Boyba K. Diop, Cécile K. Lopez, Michaela Fontenay, Philippe Dessen, Ivo P. Touw, Thomas Mercher, Said Aoufouchi, Olivier A. Bernard
Publikováno v:
Blood Advances, Vol 2, Iss 6, Pp 703-714 (2018)
Abstract: The TET2 gene encodes an α-ketoglutarate–dependent dioxygenase able to oxidize 5-methylcytosine into 5-hydroxymethylcytosine, which is a step toward active DNA demethylation. TET2 is frequently mutated in myeloid malignancies but also in
Externí odkaz:
https://doaj.org/article/720969fbdbde47808b2dd1855942e27e
Autor:
Olivier A. Bernard, Florence Nguyen-Khac, Seishi Ogawa, Nathalie Droin, Thomas Mercher, William Vainchenker, Koichi Akashi, Eric Solary, Philippe Dessen, Laurent Sutton, Hélène Merle-Béral, Daniel Gautheret, Jérôme Lambert, Frederick Davi, Yoshikane Kikushige, Satoru Miyano, Hiroko Tanaka, Kenichi Chiba, Yuichi Shiraishi, Laurianne Scourzic, M'boyba Diop, Enguerran Mouly, Véronique Della Valle, Kenichi Yoshida, Adrien Cosson, Elena Mylonas, Frederik Damm
XLS file - 75KB, Details of signature and expression analyses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b97f1d81e45ec8af17f3b3b77670c0
https://doi.org/10.1158/2159-8290.22531780
https://doi.org/10.1158/2159-8290.22531780
