Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Olivier, Tabary"'
Autor:
Christie Mitri, Zhengzhong Xu, Pauline Bardin, Harriet Corvol, Lhousseine Touqui, Olivier Tabary
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Cystic fibrosis (CF) is the most common genetic disorder among Caucasians, estimated to affect more than 70,000 people in the world. Severe and persistent bronchial inflammation and chronic bacterial infection, along with airway mucus obstruction, ar
Externí odkaz:
https://doaj.org/article/8b5f978c7d3a4c3cb3025ba2c69b94ab
Publikováno v:
Cells, Vol 10, Iss 11, p 2867 (2021)
Cystic fibrosis (CF) is the most common of rare hereditary diseases in Caucasians, and it is estimated to affect 75,000 patients globally. CF is a complex disease due to the multiplicity of mutations found in the CF transmembrane conductance regulato
Externí odkaz:
https://doaj.org/article/63e306b9919c4de784585f452d0ec962
MicroRNA-9 downregulates the ANO1 chloride channel and contributes to cystic fibrosis lung pathology
Autor:
Florence Sonneville, Manon Ruffin, Christelle Coraux, Nathalie Rousselet, Philippe Le Rouzic, Sabine Blouquit-Laye, Harriet Corvol, Olivier Tabary
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Downregulation of the anoctamin 1 calcium channel in airway epithelial cells contributes to pathology in cystic fibrosis. Here the authors show that microRNA-9 targets anoctamin 1 and that inhibiting this interaction improves mucus dynamics in mouse
Externí odkaz:
https://doaj.org/article/ebe9c1b9abb94fe688798f585d120b14
Autor:
Pauline Bardin, Tobias Foussignière, Nathalie Rousselet, Carine Rebeyrol, Joanna C. Porter, Harriet Corvol, Olivier Tabary
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Cystic fibrosis (CF) results from deficient CF transmembrane conductance regulator (CFTR) protein activity leading to defective epithelial ion transport. Pulmonary degradation due to excessive inflammation is the main cause of morbidity and mortality
Externí odkaz:
https://doaj.org/article/2a645916881b4bbc9c54f1e41362ea1b
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene and remains the most common life-shortening diseases affecting the exocrine organs. The absence of this channel results in an imbalance
Externí odkaz:
https://doaj.org/article/6a233c8e33a149c79ae8619d09fd836e
Autor:
Anastasia Tchoukaev, Jessica Taytard, Nathalie Rousselet, Carine Rebeyrol, Dominique Debray, Sabine Blouquit-Laye, Marie-Pierre Moisan, Aline Foury, Loic Guillot, Harriet Corvol, Olivier Tabary, Philippe Le Rouzic
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Cystic fibrosis (CF) is characterized by a chronic pulmonary inflammation. In CF, glucocorticoids (GC) are widely used, but their efficacy and benefit/risk ratio are still debated. In plasma, corticosteroid-binding globulin (CBG) binds 90% of GC and
Externí odkaz:
https://doaj.org/article/91e1ba35d81f4529b9baa0146696bcf0
Autor:
Alexia Plocque, Christie Mitri, Charlène Lefèvre, Olivier Tabary, Lhousseine Touqui, Francois Philippart
Publikováno v:
Drugs.
Severe manifestations of COVID-19 consist of acute respiratory distress syndrome due to an initially local reaction leading to a systemic inflammatory response that results in hypoxia. Many therapeutic approaches have been attempted to reduce the cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6184b2d38b97a33996380eb7516f3f0b
https://pubmed.ncbi.nlm.nih.gov/36508116
https://pubmed.ncbi.nlm.nih.gov/36508116
Autor:
Viviane Balloy, Hugo Varet, Marie-Agnès Dillies, Caroline Proux, Bernd Jagla, Jean-Yves Coppée, Olivier Tabary, Harriet Corvol, Michel Chignard, Loïc Guillot
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140979 (2015)
In cystic fibrosis (CF), Pseudomonas aeruginosa is not eradicated from the lower respiratory tract and is associated with epithelial inflammation that eventually causes tissue damage. To identify the molecular determinants of an effective response to
Externí odkaz:
https://doaj.org/article/b32d258454584f06b3d7103d2bad11e3
Publikováno v:
médecine/sciences
médecine/sciences, EDP Sciences, 2018, 34 (6-7), pp.554-562. ⟨10.1051/medsci/20183406015⟩
médecine/sciences, EDP Sciences, 2018, 34 (6-7), pp.554-562. ⟨10.1051/medsci/20183406015⟩
International audience; La mucoviscidose est la plus fréquente des maladies génétiques dans les populations d’origine caucasienne, caractérisée par des mutations du gène codant le canal chlorure CFTR. Bien que ce gène soit connu depuis 1989,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8a94cba753fdb73d39f041f8428bd89
https://doi.org/10.1051/medsci/20183406015
https://doi.org/10.1051/medsci/20183406015
Autor:
Pauline, Bardin, Emmeline, Marchal-Duval, Florence, Sonneville, Sabine, Blouquit-Laye, Nathalie, Rousselet, Philippe, Le Rouzic, Harriet, Corvol, Olivier, Tabary
Publikováno v:
The Journal of pathology and bacteriology
The Journal of pathology and bacteriology, John Wiley & Sons, 2018, 245 (4), pp.410-420. ⟨10.1002/path.5095⟩
The Journal of pathology and bacteriology, John Wiley & Sons, 2018, 245 (4), pp.410-420. ⟨10.1002/path.5095⟩
International audience; Cystic fibrosis (CF) is the most common lethal genetic disease, caused by CFTR (cystic fibrosis transmembrane conductance regulator) gene mutations. CF is characterized by an ionic imbalance and thickened mucus, which impair m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f906c6f3a0ccd6cf360edc36c538067d
https://www.hal.inserm.fr/inserm-02390385
https://www.hal.inserm.fr/inserm-02390385
