Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Olivia W. Lee"'
Autor:
Lindsay M. Morton, Olivia W. Lee, Danielle M. Karyadi, Tetiana I. Bogdanova, Chip Stewart, Stephen W. Hartley, Charles E. Breeze, Sara J. Schonfeld, Elizabeth K. Cahoon, Vladimir Drozdovitch, Sergii Masiuk, Mykola Chepurny, Liudmyla Yu Zurnadzhy, Jieqiong Dai, Marko Krznaric, Meredith Yeager, Amy Hutchinson, Belynda D. Hicks, Casey L. Dagnall, Mia K. Steinberg, Kristine Jones, Komal Jain, Ben Jordan, Mitchell J. Machiela, Eric T. Dawson, Vibha Vij, Julie M. Gastier-Foster, Jay Bowen, Kiyohiko Mabuchi, Maureen Hatch, Amy Berrington de Gonzalez, Gad Getz, Mykola D. Tronko, Gerry A. Thomas, Stephen J. Chanock
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Childhood radioactive iodine exposure from the Chornobyl accident increased papillary thyroid carcinoma (PTC) risk. While cervical lymph node metastases (cLNM) are well-recognized in pediatric PTC, the PTC metastatic process and potential ra
Externí odkaz:
https://doaj.org/article/43b4a3f2d4b34656b884b3b550e5f0f9
Autor:
Derek W. Brown, Weiyin Zhou, Youjin Wang, Kristine Jones, Wen Luo, Casey Dagnall, Kedest Teshome, Alyssa Klein, Tongwu Zhang, Shu-Hong Lin, Olivia W. Lee, Sairah Khan, Jacqueline B. Vo, Amy Hutchinson, Jia Liu, Jiahui Wang, Bin Zhu, Belynda Hicks, Andrew St. Martin, Stephen R. Spellman, Tao Wang, H. Joachim Deeg, Vikas Gupta, Stephanie J. Lee, Neal D. Freedman, Meredith Yeager, Stephen J. Chanock, Sharon A. Savage, Wael Saber, Shahinaz M. Gadalla, Mitchell J. Machiela
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Myelofibrosis is a risk factor for the development of Acute Myeloid Leukaemia. Here, the authors carry out an integrated genomic investigation of 933 myelofibrosis patients, and identified interactions between germline and somatic variation in patien
Externí odkaz:
https://doaj.org/article/ab44e678038343a49f55b6e7f9217d06
Autor:
Robert W. Robey, Andrea N. Robinson, Fatima Ali-Rahmani, Lyn M. Huff, Sabrina Lusvarghi, Shahrooz Vahedi, Jordan M. Hotz, Andrew C. Warner, Donna Butcher, Jennifer Matta, Elijah F. Edmondson, Tobie D. Lee, Jacob S. Roth, Olivia W. Lee, Min Shen, Kandice Tanner, Matthew D. Hall, Suresh V. Ambudkar, Michael M. Gottesman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Capillary endothelial cells of the human blood–brain barrier (BBB) express high levels of P-glycoprotein (P-gp, encoded by ABCB1) and ABCG2 (encoded by ABCG2). However, little information is available regarding ATP-binding cassette transpo
Externí odkaz:
https://doaj.org/article/d695e11725554b04bae4d6fdca65d5b1
Autor:
Shu-Hong Lin, Derek W. Brown, Brandon Rose, Felix Day, Olivia W. Lee, Sairah M. Khan, Jada Hislop, Stephen J. Chanock, John R. B. Perry, Mitchell J. Machiela
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Background Mosaic chromosomal alterations (mCAs) are large chromosomal gains, losses and copy-neutral losses of heterozygosity (LOH) in peripheral leukocytes. While many individuals with detectable mCAs have no notable adverse outcomes, mCA-
Externí odkaz:
https://doaj.org/article/f60dab5e4ee841b4a1c49e27396c5a3e
Autor:
Olivia W. Lee, Calvin Rodrigues, Shu-Hong Lin, Wen Luo, Kristine Jones, Derek W. Brown, Weiyin Zhou, Eric Karlins, Sairah M. Khan, Sylvain Baulande, Virginie Raynal, Didier Surdez, Stephanie Reynaud, Rebeca Alba Rubio, Sakina Zaidi, Sandrine Grossetête, Stelly Ballet, Eve Lapouble, Valérie Laurence, Gaelle Pierron, Nathalie Gaspar, Nadège Corradini, Perrine Marec-Bérard, Nathaniel Rothman, Casey L. Dagnall, Laurie Burdett, Michelle Manning, Kathleen Wyatt, Meredith Yeager, Raj Chari, Wendy M. Leisenring, Andreas E. Kulozik, Jennifer Kriebel, Thomas Meitinger, Konstantin Strauch, Thomas Kirchner, Uta Dirksen, Lisa Mirabello, Margaret A. Tucker, Franck Tirode, Gregory T. Armstrong, Smita Bhatia, Leslie L. Robison, Yutaka Yasui, Laura Romero-Pérez, Wolfgang Hartmann, Markus Metzler, W. Ryan Diver, Adriana Lori, Neal D. Freedman, Robert N. Hoover, Lindsay M. Morton, Stephen J. Chanock, Thomas G.P. Grünewald, Olivier Delattre, Mitchell J. Machiela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f130d0b63d38427a5a265ccc0fc8f83c
https://www.ncbi.nlm.nih.gov/pubmed/36787739
https://www.ncbi.nlm.nih.gov/pubmed/36787739
Autor:
Matthew D. Hall, Xin Xu, Pranav Shah, Olivia W. Lee, Min Shen, Hu Zhu, Samarjit Patnaik, Ajit Jadhav
Publikováno v:
SLAS Discov
Fumarate hydratase (FH) is a metabolic enzyme that is part of the Krebs-cycle, and reversibly catalyzes the hydration of fumarate to malate. Mutations of the FH gene have been associated with fumarate hydratase deficiency (FHD), hereditary leiomyomat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa439d9b9bbe84f73acc652d7ef0982b
https://doi.org/10.1177/2472555219873559
https://doi.org/10.1177/2472555219873559
Autor:
Min Shen, Donna Butcher, Olivia W. Lee, Robert W. Robey, Elijah F. Edmondson, Kandice Tanner, Jacob S. Roth, Matthew D. Hall, Andrea N. Robinson, Tobie D. Lee, Michael M. Gottesman, Fatima Ali-Rahmani, Jennifer L Matta, Shahrooz Vahedi, Sabrina Lusvarghi, Jordan M. Hotz, Suresh V. Ambudkar, Lyn M. Huff, Andrew C. Warner
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
Given its similarities with mammalian systems, the zebrafish has emerged as a potential model to study the blood-brain barrier (BBB). Capillary endothelial cells at the human BBB express high levels of P-glycoprotein (P-gp, encoded by the ABCB1 gene)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72705e658a705f5d6b4fb4cb0bdf6668
https://doi.org/10.1038/s41598-021-03500-8
https://doi.org/10.1038/s41598-021-03500-8
Autor:
Felix R. Day, Brandon Rose, Derek Brown, Stephen J. Chanock, Olivia W. Lee, Shu-Hong Lin, Sairah M. Khan, John R. B. Perry, Jada Hislop, Mitchell J. Machiela
Publikováno v:
Cell & Bioscience
Cell & Bioscience, Vol 11, Iss 1, Pp 1-11 (2021)
Cell & Bioscience, Vol 11, Iss 1, Pp 1-11 (2021)
Funder: Division of Cancer Epidemiology and Genetics, National Cancer Institute; doi: http://dx.doi.org/10.13039/100011541
Funder: National Cancer Institute (NCI)
Background: Mosaic chromosomal alterations (mCAs) are large chromosomal gains
Funder: National Cancer Institute (NCI)
Background: Mosaic chromosomal alterations (mCAs) are large chromosomal gains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa34b623b5e667869e6a234e629cc2fa
https://doi.org/10.1186/s13578-021-00651-z
https://doi.org/10.1186/s13578-021-00651-z
Autor:
Olivia W. Lee, Matthew B. Boxer, Manshu Tang, Matthew D. Hall, Kent Lai, Li Liu, Xin Hu, Yaqin Zhang, Min Shen
Publikováno v:
Journal of Computer-Aided Molecular Design. 33:405-417
Classic Galactosemia is a potentially lethal autosomal recessive metabolic disorder caused by deficient galactose-1-phosphate uridyltransferase (GALT) that results in the buildup of galactose-1-phosphate (gal-1-p) in cells. Galactokinase (GALK1) is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65be7179c4e545f7ad1dec7417e2179e
https://doi.org/10.1007/s10822-019-00190-3
https://doi.org/10.1007/s10822-019-00190-3
Autor:
Olivia W. Lee, Danielle M. Karyadi, Chip Stewart, Tetiana I. Bogdanova, Jieqiong Dai, Stephen W. Hartley, Sara J. Schonfeld, Vidushi Kapoor, Marko Krznaric, Meredith Yeager, Amy Hutchinson, Belynda D. Hicks, Casey L. Dagnall, Julie M. Gastier-Foster, Jay Bowen, Mitchell J. Machiela, Elizabeth K. Cahoon, Kiyohiko Mabuchi, Vladimir Drozdovitch, Sergii Masiuk, Mykola Chepurny, Liudmyla Y. Zurnadzhy, Amy Berrington de González, Gad Getz, Gerry A. Thomas, Mykola D. Tronko, Lindsay M. Morton, Stephen J. Chanock
Publikováno v:
Cancer Research. 82:980-980
Following the Chernobyl nuclear power plant explosion in Ukraine in 1986, increased childhood exposure to radioactive iodine (131I), which occurred primarily through contaminated food sources, has been consistently associated with increased risk of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d38fb0de96b86c7a1a0911071919eec0
https://doi.org/10.1158/1538-7445.am2022-980
https://doi.org/10.1158/1538-7445.am2022-980