Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Olivia Slater"'
Autor:
Olivia Slater, Maria Kontoyianni
Publikováno v:
SN Applied Sciences, Vol 4, Iss 5, Pp 1-19 (2022)
Abstract The somatostatin subtype-4 receptor (sst4) is highly expressed in neocortical and hippocampal areas, which are affected by amyloid beta accumulation. Sst4 agonists enhance downstream activity of amyloid beta peptide catabolism through nepril
Externí odkaz:
https://doaj.org/article/509926581c3c41a6aa396ad66f237ed7
Autor:
Olivia Slater, Kapur B. Dhami, Ganesh Shrestha, Maria Kontoyianni, Michael R. Nichols, Alexei V. Demchenko
Publikováno v:
ACS Infect Dis
Sepsis is a serious medical condition characterized by bacterial infection and a subsequent massive systemic inflammatory response. In an effort to identify compounds that block lipopolysaccharide (LPS)-induced inflammation reported herein is the dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850fe349441a73af2495ff7a9bd060f8
https://europepmc.org/articles/PMC9402072/
https://europepmc.org/articles/PMC9402072/
Autor:
William L. Neumann, Karin E. Sandoval, Shirin Mobayen, Mahsa Minaeian, Stephen G. Kukielski, Khush N. Srabony, Rafael Frare, Olivia Slater, Susan A. Farr, Michael L. Niehoff, Audrey Hospital, Maria Kontoyianni, A. Michael Crider, Ken A. Witt
Publikováno v:
RSC Med Chem
Somatostatin receptor-4 (SST(4)) is highly expressed in brain regions affiliated with learning and memory. SST(4) agonist treatment may act to mitigate Alzheimer's disease (AD) pathology. An integrated approach to SST(4) agonist lead optimization is
Publikováno v:
Microsoft Academic Graph
Drug discovery has focused on the paradigm “one drug, one target” for a long time. However, small molecules can act at multiple macromolecular targets, which serves as the basis for drug repurposing. In an effort to expand the target space, and g
Autor:
Maria Kontoyianni, Olivia Slater
Publikováno v:
Expert Opinion on Drug Discovery. 14:619-637
Introduction: Docking and structure-based virtual screening (VS) have been standard approaches in structure-based design for over two decades. However, our understanding of the limitations, potential, and strength of these techniques has enhanced, ra
Autor:
Favour Akabogu, Casey Tetidrick, Sarah A. Blank, Willie Gosnell, Aubrey Melton, Sandra Meneses, Robin Hauschner, Ronald Rosen, Olivia Slater
Publikováno v:
Comparative Parasitology. 85:202-207
The effect of temperature on cercarial release has been well documented for several digenean species; however, there have been no prior studies assessing shedding of cercariae from snails infected with the azygiid, Proterometra macrostoma. Snails, Pl
Autor:
Favour Akabogu, Kaitlyn Reasoner, Ronald Rosen, Lin Peng, Robin Hauschner, Olivia Slater, Chi Peng, Hsuan Peng, Sandra Meneses
Publikováno v:
Comparative Parasitology. 84:169-173
The objective of this study was to assess seasonal changes in the maturation of adult Cotylaspis insignis recovered from the gill and visceral mass junction of the fat mucket, Lampsilis radiata luteola, over 14 months. Mussels were collected from Nor