Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Olivia Sheppard"'
Autor:
Lauren V. C. Miller, Aamir S. Mukadam, Claire S. Durrant, Marina J. Vaysburd, Taxiarchis Katsinelos, Benjamin J. Tuck, Sophie Sanford, Olivia Sheppard, Claire Knox, Shi Cheng, Leo C. James, Michael P. Coleman, William A. McEwan
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-16 (2021)
Abstract A fundamental property of infectious agents is their particulate nature: infectivity arises from independently-acting particles rather than as a result of collective action. Assemblies of the protein tau can exhibit seeding behaviour, potent
Externí odkaz:
https://doaj.org/article/8c71a3da926645f4b60a31a290b71149
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-13 (2019)
Abstract Background Systemic inflammation has been linked to synapse loss and cognitive decline in human patients and animal models. A role for microglial release of pro-inflammatory cytokines has been proposed based on in vivo and primary culture st
Externí odkaz:
https://doaj.org/article/e9d4229fb16142aca6787e5587d40e32
Autor:
Jing Qiu, Jamie McQueen, Bilada Bilican, Owen Dando, Dario Magnani, Karolina Punovuori, Bhuvaneish T Selvaraj, Matthew Livesey, Ghazal Haghi, Samuel Heron, Karen Burr, Rickie Patani, Rinku Rajan, Olivia Sheppard, Peter C Kind, T Ian Simpson, Victor LJ Tybulewicz, David JA Wyllie, Elizabeth MC Fisher, Sally Lowell, Siddharthan Chandran, Giles E Hardingham
Publikováno v:
eLife, Vol 5 (2016)
Evolutionary differences in gene regulation between humans and lower mammalian experimental systems are incompletely understood, a potential translational obstacle that is challenging to surmount in neurons, where primary tissue availability is poor.
Externí odkaz:
https://doaj.org/article/c6d2491c1b8445d08c27122e7a5f0b19
Autor:
Susan M Gribble, Frances K Wiseman, Stephen Clayton, Elena Prigmore, Elizabeth Langley, Fengtang Yang, Sean Maguire, Beiyuan Fu, Diana Rajan, Olivia Sheppard, Carol Scott, Heidi Hauser, Philip J Stephens, Lucy A Stebbings, Bee Ling Ng, Tomas Fitzgerald, Michael A Quail, Ruby Banerjee, Kai Rothkamm, Victor L J Tybulewicz, Elizabeth M C Fisher, Nigel P Carter
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60482 (2013)
Down syndrome (DS) is caused by trisomy of chromosome 21 (Hsa21) and presents a complex phenotype that arises from abnormal dosage of genes on this chromosome. However, the individual dosage-sensitive genes underlying each phenotype remain largely un
Externí odkaz:
https://doaj.org/article/40d01f7c551e41a4a19b62b717840f84
Autor:
Olivia Sheppard, Frances K. Wiseman, Aarti Ruparelia, Victor L. J. Tybulewicz, Elizabeth M. C. Fisher
Publikováno v:
The Scientific World Journal, Vol 2012 (2012)
Abnormalities of chromosome copy number are called aneuploidies and make up a large health load on the human population. Many aneuploidies are lethal because the resulting abnormal gene dosage is highly deleterious. Nevertheless, some whole chromosom
Externí odkaz:
https://doaj.org/article/a6d28d19ca164bcebb302effe04b2c87
Publikováno v:
Nanotechnology. 34:145401
In this study, composite asymmetric membranes containing antimony (Sb) nanobelts are prepared via a straightforward phase inversion method in combination with post-pyrolysis treatment. Sb nanobelt asymmetric membranes demonstrate improved cyclability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91345e9d73b36976f28d25fdb40868f4
https://doi.org/10.1088/1361-6528/acb15c
https://doi.org/10.1088/1361-6528/acb15c
Publikováno v:
ECS Meeting Abstracts. :2300-2300
The standard lithium-ion battery (LIB) using graphite electrodes has become exceedingly important in today’s world. Everything from electric cars to solar energy storage systems need these batteries, and the capabilities and progress of these devic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1520ee24837ae76267018357fd060a6
https://doi.org/10.1149/ma2022-02642300mtgabs
https://doi.org/10.1149/ma2022-02642300mtgabs
Autor:
Marina Vaysburd, Sophie Sanford, Benjamin J. Tuck, Shi Cheng, Claire Knox, Leo C. James, Michael P. Coleman, Taxiarchis Katsinelos, Aamir S. Mukadam, Claire S. Durrant, William A. McEwan, Olivia Sheppard, Lauren V. C. Miller
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-16 (2021)
Miller, L, Mukadam, A, Durrant, C, Vaysburd, M, Katsinelos, T, Tuck, B, Sanford, S, Sheppard, O, Knox, C, Cheng, S, James, L, Coleman, M & McEwan, W 2021, ' Tau assemblies do not behave like independently acting prion-like particles in mouse neural tissue ', Acta Neuropathologica Communications, vol. 9, no. 41, 41 . https://doi.org/10.1186/s40478-021-01141-6
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-16 (2021)
Miller, L, Mukadam, A, Durrant, C, Vaysburd, M, Katsinelos, T, Tuck, B, Sanford, S, Sheppard, O, Knox, C, Cheng, S, James, L, Coleman, M & McEwan, W 2021, ' Tau assemblies do not behave like independently acting prion-like particles in mouse neural tissue ', Acta Neuropathologica Communications, vol. 9, no. 41, 41 . https://doi.org/10.1186/s40478-021-01141-6
A fundamental property of infectious agents is their particulate nature: infectivity arises from independently-acting particles rather than as a result of collective action. Assemblies of the protein tau can exhibit seeding behaviour, potentially und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419dabafedfc769c8945adc1bc687155
https://www.repository.cam.ac.uk/handle/1810/318719
https://www.repository.cam.ac.uk/handle/1810/318719
Autor:
Olivia Sheppard, Michael P. Coleman
Publikováno v:
Alzheimer’s Disease: Drug Discovery ISBN: 9780645001709
Alzheimer’s disease is the most common form of dementia and the most common neurodegenerative disease. It manifests as a decline in short-term memory and cognition that impairs daily behavior. Most cases of Alzheimer’s disease are sporadic, but a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::045aa69e388edd0f2b4c7cd4bf00739e
https://doi.org/10.36255/exonpublications.alzheimersdisease.2020.ch1
https://doi.org/10.36255/exonpublications.alzheimersdisease.2020.ch1
Autor:
Olivia Sheppard, Jake DiCesare, Shaowen Xu, Ji Wu, Xiaobo Chen, Congrui Jin, Emilee Larson, Logan Williams
Publikováno v:
Journal of Materials Research. 37:2225-2225
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4efded5f0eed7a98c0e2ffb889a5381
https://doi.org/10.1557/s43578-021-00414-z
https://doi.org/10.1557/s43578-021-00414-z