Výsledky vyhledávání - "Olivia Seale"

Non-peptidyl small molecule, adenosine, 5′-Se-methyl-5′-seleno-, 2′,3′-diacetate, activates insulin receptor and attenuates hyperglycemia in type 2 diabetic Leprdb/db mice

Autor: Zhenmin Lei, Xian Li, Zi-Jian Lan, Thirupathi Reddy Yerramreddy, Hannah Gadberry, Lei Lei, Ronan Power, Olivia Seale, Hayley Kincaid, Katie Eastridge, Chloe Power, Rijin Xiao, Karl Dawson, Alexandros Yiannikouris

Publikováno v: Cellular and Molecular Life Sciences

The pathophysiology of type 2 diabetes mellitus (T2D) is characterized by reduced or absent insulin receptor (INSR) responsiveness to its ligand, elevated hepatic glucose output and impaired glucose uptake in peripheral tissues, particularly skeletal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05fdba08620f6183a96bfce197ad6fb
https://doi.org/10.1007/s00018-019-03249-4

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