Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Olivia S Rissland"'
Autor:
Kristen J Wade, Samantha Tisa, Chloe Barrington, Jesslyn C Henriksen, Kristy R Crooks, Christopher R Gignoux, Austin T Almand, J Jordan Steel, John C Sitko, Joseph W Rohrer, Douglas P Wickert, Erin A Almand, David D Pollock, Olivia S Rissland
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0274050 (2022)
Since the initial reported discovery of SARS-CoV-2 in late 2019, genomic surveillance has been an important tool to understand its transmission and evolution. Here, we sought to describe the underlying regional phylodynamics before and during a rapid
Externí odkaz:
https://doaj.org/article/40f82ee8be09455e8337d3cf9e3f0bc6
Autor:
Michael Zavortink, Lauren N Rutt, Svetlana Dzitoyeva, Jesslyn C Henriksen, Chloe Barrington, Danielle Y Bilodeau, Miranda Wang, Xiao Xiao Lily Chen, Olivia S Rissland
Publikováno v:
eLife, Vol 9 (2020)
The maternal-to-zygotic transition (MZT) is a conserved step in animal development, where control is passed from the maternal to the zygotic genome. Although the MZT is typically considered from its impact on the transcriptome, we previously found th
Externí odkaz:
https://doaj.org/article/d9c1b57f26f64ef38cdd74811f0c8152
Autor:
Miranda Wang, Michael Ly, Andrew Lugowski, John D Laver, Howard D Lipshitz, Craig A Smibert, Olivia S Rissland
Publikováno v:
eLife, Vol 6 (2017)
In animal embryos, control of development is passed from exclusively maternal gene products to those encoded by the embryonic genome in a process referred to as the maternal-to-zygotic transition (MZT). We show that the RNA-binding protein, ME31B, bi
Externí odkaz:
https://doaj.org/article/eaede19c8aa14e899a9a1fb0f6b75940
Autor:
Chloe L. Barrington, Gabriel Galindo, Amanda L. Koch, Emma R. Horton, Evan J. Morrison, Samantha Tisa, Timothy J. Stasevich, Olivia S. Rissland
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113413- (2023)
Summary: Nonoptimal synonymous codons repress gene expression, but the underlying mechanisms are poorly understood. We and others have previously shown that nonoptimal codons slow translation elongation speeds and thereby trigger messenger RNA (mRNA)
Externí odkaz:
https://doaj.org/article/b3483aeae2a8422cb39ab1f4d60698c3
Autor:
Deivid C. Rodrigues, Marat Mufteev, Kyoko E. Yuki, Ashrut Narula, Wei Wei, Alina Piekna, Jiajie Liu, Peter Pasceri, Olivia S. Rissland, Michael D. Wilson, James Ellis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the transcriptional modulator MECP2. Here, the authors measured transcription rate and mRNA half-life changes in RTT patient-derived neurons to show transcription rate buffer
Externí odkaz:
https://doaj.org/article/097209b23fed40c18a9738ecdd5640cd
Autor:
Farnaz Mansouri-Noori, Andreas Pircher, Danielle Bilodeau, Lidia Siniavskaia, Jörg Grigull, Olivia S. Rissland, Mark A. Bayfield
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113226- (2023)
Summary: Messenger RNAs (mRNAs) in higher eukaryotes that encode proteins important for the assembly of the translational apparatus (e.g., ribosomal proteins) often harbor a pyrimidine-rich motif at the extreme 5′ end known as a 5′ terminal oligo
Externí odkaz:
https://doaj.org/article/24ab6f9c7cd04ee4847d6c7bacf5e1ca
Publikováno v:
RNA. 29:596-608
The maternal-to-zygotic transition (MZT) is a conserved embryonic process in animals where developmental control shifts from the maternal to zygotic genome. A key step in this transition is zygotic transcription, and deciphering the MZT requires clas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4385d9ad12c7383afdf507ac07f670
https://doi.org/10.1261/rna.079168.122
https://doi.org/10.1261/rna.079168.122
Autor:
Olivia S. Rissland, Alexander O. Subtelny, Miranda Wang, Andrew Lugowski, Beth Nicholson, John D. Laver, Sachdev S. Sidhu, Craig A. Smibert, Howard D. Lipshitz, David P. Bartel
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-18 (2017)
Abstract Background All mRNAs are bound in vivo by proteins to form mRNA–protein complexes (mRNPs), but changes in the composition of mRNPs during posttranscriptional regulation remain largely unexplored. Here, we have analyzed, on a transcriptome-
Externí odkaz:
https://doaj.org/article/d95ae799118d42feb5cbf376b05785f8
Autor:
Marat Mufteev, Deivid C. Rodrigues, Kyoko E. Yuki, Ashrut Narula, Wei Wei, Alina Piekna, Jiajie Liu, Peter Pasceri, Olivia S. Rissland, Michael D. Wilson, James Ellis
The contribution of mRNA half-life is commonly overlooked when examining changes in mRNA abundance during development. mRNA levels of some genes are regulated by transcription rate only, but others may be regulated by mRNA half-life only shifts. Furt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d2ca43de6cbb75fa4382705cfa178b7
https://doi.org/10.1101/2023.03.01.530249
https://doi.org/10.1101/2023.03.01.530249
Publikováno v:
RNA. 28:668-682
During pre-mRNA processing, the poly(A) signal is recognized by a protein complex that ensures precise cleavage and polyadenylation of the nascent transcript. The location of this cleavage event establishes the length and sequence of the 3′ UTR of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16aa9be0f424a3a2e0bbece765121f1b
https://doi.org/10.1261/rna.078793.121
https://doi.org/10.1261/rna.078793.121