Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Olivia R Brohlin"'
Autor:
Fabian C. Herbert, Sameera S. Abeyrathna, Nisansala S. Abeyrathna, Yalini H. Wijesundara, Olivia R. Brohlin, Francesco Carraro, Heinz Amenitsch, Paolo Falcaro, Michael A. Luzuriaga, Alejandra Durand-Silva, Shashini D. Diwakara, Ronald A. Smaldone, Gabriele Meloni, Jeremiah J. Gassensmith
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Stabilizing lipid nanoparticles and lipidprotein assemblies is challenging owing to lipid dynamics and protein instability. Here, the authors report on the reversible encapsulation of liposomes and proteoliposomes in a metalorganic framework permitti
Externí odkaz:
https://doaj.org/article/6c63006885b6455ba0e68e5b925e37f0
Autor:
Yalini H. Wijesundara, Fabian C. Herbert, Orikeda Trashi, Ikeda Trashi, Olivia R. Brohlin, Sneha Kumari, Thomas Howlett, Candace E. Benjamin, Arezoo Shahrivarkevishahi, Shashini D. Diwakara, Sachini D. Perera, Samuel A. Cornelius, Juan P. Vizuet, Kenneth J. Balkus, Ronald A. Smaldone, Nicole J. De Nisco, Jeremiah J. Gassensmith
Publikováno v:
Chemical Science. 13:13803-13814
The efficacy and specificity of protein, DNA, and RNA-based drugs have made them popular in the clinic; however, their susceptibility to environmental stressors adds significant challenges to formulating biomacromolecules into delivery systems where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60cc456fd1e1120991f0a32abfd2d3f6
https://doi.org/10.1039/d2sc04982a
https://doi.org/10.1039/d2sc04982a
Autor:
Jashkaran Gadhvi, Olivia R. Brohlin, Hamilton Lee, Jeremiah J. Gassensmith, Alisia C. Tumac, Nicole J. De Nisco, Yalini H. Wijesundara, Michael A. Luzuriaga, Fabian C. Herbert, Abhinay V. Adlooru, Perouza Parsamian, Arezoo Shahrivarkevishahi, Candace E. Benjamin
Publikováno v:
Journal of the American Chemical Society. 143:16428-16438
Virus-like particles (VLPs) are multifunctional nanocarriers that mimic the architecture of viruses. They can serve as a safe platform for specific functionalization and immunization, which provides benefits in a wide range of biomedical applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b5c4a7b873f67d80e56f0b45ec2682
https://doi.org/10.1021/jacs.1c05090
https://doi.org/10.1021/jacs.1c05090
Autor:
Arezoo Shahrivarkevishahia, Laurel M. Hagge, Olivia R Brohlin, Sneha Kumari, Ryanne Ehrman, Candace Benjamin, Jeremiah Gassensmith
Nanoparticle-based therapeutics have been applied in a broad range of clinical and pre-clinical applications from diagnosis to treatment for cancer. A wide range of synthetic and naturally occurring materials such as polymers, metal oxides, silicate,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38354cecf31977c965d89b9ce754d46e
https://doi.org/10.26434/chemrxiv-2022-bhjbr
https://doi.org/10.26434/chemrxiv-2022-bhjbr
Autor:
Olivia R. Brohlin, Ryanne N. Ehrman, Fabian C. Herbert, Yalini H. Wijesundara, Arun Raja, Arezoo Shahrivarkevishahi, Shashini D. Diwakara, Ronald A. Smaldone, Jeremiah J. Gassensmith
Metal-organic frameworks (MOFs) have been used to improve vaccine formulations by stabilizing proteins and protecting them against thermal degradation. This has led to increased 2 immunogenicity of these proteinaceous therapeutics. In this work we sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00546a687ecd12e0db2bf7dbfa8a813c
https://doi.org/10.26434/chemrxiv-2021-cdpf5
https://doi.org/10.26434/chemrxiv-2021-cdpf5
Autor:
Fabian Castro, Hamilton Lee, Laurel M. Hagge, Zhuo Chen, Abhinay V. Adlooru, Sindhu Ponnam, HamidReza Firouzi, Arezoo Shahrivarkevishahi, Olivia R. Brohlin, Jeremiah J. Gassensmith, Alisia C. Tumac
Intracellular targeting is an important aspect of the efficient delivery of drugs and nanotherapeutics. Cytosolic transport of nanomaterials is often an essential requirement for therapeutic delivery into cells but remains a challenge owing to the en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88e691ecb8ffef96da14205ce053ff2f
https://doi.org/10.26434/chemrxiv-2021-g3rld
https://doi.org/10.26434/chemrxiv-2021-g3rld
Autor:
Fabian C. Herbert, Perouza Parsamian, Hamilton Lee, Olivia R. Brohlin, Jeremiah J. Gassensmith, Alisia C. Tumac, Arezoo Shahrivarkevishahi, Candace E. Benjamin, Michael A. Luzuriaga, Yalini H. Wijesundara
Virus like particles (VLPs) are non-infectious multifunctional nanocarriers with the pathogenic-like architecture of viruses. They can serve as a safe platform for precise functionalization and immunization, which provides benefits in a wide range of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b6591363785ebb5f4abd2f5999a6db
https://doi.org/10.33774/chemrxiv-2021-gl4s5-v2
https://doi.org/10.33774/chemrxiv-2021-gl4s5-v2
Autor:
Michael A. Luzuriaga, Jeremiah J. Gassensmith, Olivia R. Brohlin, Arezoo Shahrivarkevishahi, Hamilton Lee, Laurel M. Hagge, Darby Ball, Jenica L. Lumata, Sheena D'Arcy, Fabian C. Herbert
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Virus-like particles are an emerging class of nano-biotechnology with the Tobacco Mosaic Virus (TMV) having found a wide range of applications in imaging, drug delivery, and vaccine development. TMV is typically produced in planta, and, as an RNA vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52621e1494a349f3eb2f486288c61eb2
https://doi.org/10.21203/rs.3.rs-509112/v1
https://doi.org/10.21203/rs.3.rs-509112/v1
Autor:
Sameera S. Abeyrathna, Francesco Carraro, Gabriele Meloni, Fabian C. Herbert, Nisansala S. Abeyrathna, Shashini D. Diwakara, Michael A. Luzuriaga, Jeremiah J. Gassensmith, Paolo Falcaro, Alejandra Durand-Silva, Olivia R. Brohlin, Heinz Amenitsch, Yalini H. Wijesundara, Ronald A. Smaldone
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Artificial native-like lipid bilayer systems constructed from phospholipids assembling into unilamellar liposomes allow the reconstitution of detergent-solubilized transmembrane proteins into supramolecular lipid-protein assemblies called proteolipos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::653337063123e28e823a5acec1b03131
https://pubmed.ncbi.nlm.nih.gov/33850135
https://pubmed.ncbi.nlm.nih.gov/33850135
Autor:
Molly A. Ingersoll, Sundharamani Venkitapathi, Thomas Howlett, Nicole J. De Nisco, Michael A. Luzuriaga, Olivia R. Brohlin, Kavya Veera, Fabian C. Herbert, Jashkaran Gadhvi, Michael D. Burton, Arezoo Shahrivarkevishahi, Candace E. Benjamin, Ryanne Ehrman, Jeremiah J. Gassensmith, Yalini H. Wijesundara, Sarah Popal
Publikováno v:
ACS Nano
ACS Nano, American Chemical Society, 2021, ⟨10.1021/acsnano.1c03092⟩
ACS Nano, 2021, ⟨10.1021/acsnano.1c03092⟩
ACS Nano, American Chemical Society, 2021, ⟨10.1021/acsnano.1c03092⟩
ACS Nano, 2021, ⟨10.1021/acsnano.1c03092⟩
The increasing rate of resistance of bacterial infection against antibiotics requires next generation approaches to fight potential pandemic spread. The development of vaccines against pathogenic bacteria has been difficult owing, in part, to the gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f314c9fe1dbd1f84af7c33b1a23d374f
https://doi.org/10.1101/2020.06.14.148452
https://doi.org/10.1101/2020.06.14.148452