Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Olivia Luige"'
Publikováno v:
Molecules, Vol 29, Iss 9, p 2123 (2024)
PNAzymes are a group of artificial enzymes which show promising results in selective and efficient cleavage of RNA targets. In the present study, we introduce a series of metal chelating groups based on N,N-bis(2-picolyl) groups (parent, 6-methyl and
Externí odkaz:
https://doaj.org/article/4262e2c69d074ea8a4a3256173c9c8b6
Autor:
François Halloy, Annabelle Biscans, Katherine E. Bujold, Alexandre Debacker, Alyssa C. Hill, Aurélie Lacroix, Olivia Luige, Roger Strömberg, Linda Sundstrom, Jörg Vogel, Alice Ghidini
Publikováno v:
RNA Biology, Vol 19, Iss 1, Pp 313-332 (2022)
RNA-based therapeutics are emerging as a powerful platform for the treatment of multiple diseases. Currently, the two main categories of nucleic acid therapeutics, antisense oligonucleotides and small interfering RNAs (siRNAs), achieve their therapeu
Externí odkaz:
https://doaj.org/article/cd8fb0a6285b407a8a63465d0c07a69f
Publikováno v:
Molecules, Vol 24, Iss 4, p 672 (2019)
Peptide nucleic acid (PNA)-neocuproine conjugates have been shown to efficiently catalyse the cleavage of RNA target sequences in the presence of Cu2+ ions in a site-specific manner. These artificial enzymes are designed to force the formation of a b
Externí odkaz:
https://doaj.org/article/5e4f03eefed544b6bbabe6de9ac1487a
Autor:
Olivia Luige, Shalini Andersson, Peter Steunenberg, Roger Strömberg, Omar Brun, Partha Pratim Bose, Merita Murtola, Rouven Stulz
Publikováno v:
Chemical Communications. 57:10911-10914
Novel efficient Zn2+ dimethyl-dipyridophenazine PNA-based artificial nucleases cleave RNA site-specifically and can be tailored to different RNA targets, including RNA models originating from a malaria parasite and the SARS-CoV-2 virus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::800059d7b147ea25498bf5adf45831f1
https://doi.org/10.1039/d1cc04383h
https://doi.org/10.1039/d1cc04383h
Autor:
Olivia, Luige, Kristina, Karalė, Partha Pratim, Bose, Martin, Bollmark, Ulf, Tedebark, Merita, Murtola, Roger, Strömberg
Publikováno v:
RSC advances. 12(9)
The development of Zn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a62d6bfbc525196fbc6cf6ddfaa0ee0f
https://pubmed.ncbi.nlm.nih.gov/35425588
https://pubmed.ncbi.nlm.nih.gov/35425588
Autor:
Olivia, Luige, Partha Pratim, Bose, Rouven, Stulz, Peter, Steunenberg, Omar, Brun, Shalini, Andersson, Merita, Murtola, Roger, Strömberg
Publikováno v:
Chemical communications (Cambridge, England). 57(83)
We present Zn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a689a9bad4b3719c714d39b8853e42fd
https://pubmed.ncbi.nlm.nih.gov/34590632
https://pubmed.ncbi.nlm.nih.gov/34590632
Publikováno v:
Molecules, 24 (4)
Molecules
Volume 24
Issue 4
Molecules, Vol 24, Iss 4, p 672 (2019)
Molecules
Volume 24
Issue 4
Molecules, Vol 24, Iss 4, p 672 (2019)
Peptide nucleic acid (PNA)-neocuproine conjugates have been shown to efficiently catalyse the cleavage of RNA target sequences in the presence of Cu2+ ions in a site-specific manner. These artificial enzymes are designed to force the formation of a b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::764fd59d66dffb706b10a85752e1e796