Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Olivia L. Walker"'
Autor:
Alamelu G. Bharadwaj, Meghan E. McLean, Margaret L. Dahn, Hannah F. Cahill, Marie‐Claire D. Wasson, Raj Pranap Arun, Olivia L. Walker, Brianne M. Cruickshank, Wasundara Fernando, Jaganathan Venkatesh, Penelope J. Barnes, Gillian Bethune, Gregory Knapp, Lucy K. Helyer, Carman A. Giacomantonio, David M. Waisman, Paola Marcato
Publikováno v:
Molecular Oncology, Vol 18, Iss 1, Pp 91-112 (2024)
Aldehyde dehydrogenase 1A3 (ALDH1A3) is a cancer stem cell marker that promotes metastasis. Triple‐negative breast cancer (TNBC) progression has been linked to ALDH1A3‐induced gene expression changes. To investigate the mechanism of ALDH1A3‐med
Externí odkaz:
https://doaj.org/article/3963ad169532432cb23f181c5b3a6969
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 4102 (2024)
Cancer stem cells (CSCs) represent a subpopulation within tumors that promote cancer progression, metastasis, and recurrence due to their self-renewal capacity and resistance to conventional therapies. CSC-specific markers and signaling pathways high
Externí odkaz:
https://doaj.org/article/0bb97474ec694a6e9507fd1273b171b4
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Culprits of cancer development, metastasis, and drug resistance, cancer stem cells (CSCs) are characterized by specific markers, active developmental signaling pathways, metabolic plasticity, increased motility, invasiveness, and epithelial-mesenchym
Externí odkaz:
https://doaj.org/article/ea672c930451471e8cc2a6086fc722a4
Autor:
Margaret L. Dahn, Hayley R. Walsh, Cheryl A. Dean, Michael A. Giacomantonio, Wasundara Fernando, J Patrick Murphy, Olivia L. Walker, Marie-Claire D. Wasson, Shashi Gujar, Devanand M. Pinto, Paola Marcato
Publikováno v:
Metabolomics
Introduction Aldehyde dehydrogenase 1A3 (ALDH1A3) is a cancer stem cell (CSC) marker and in breast cancer it is associated with triple-negative/basal-like subtypes and aggressive disease. Studies on the mechanisms of ALDH1A3 in cancer have primarily
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8741b1c9e9a24d79dd525e97ff53e55e
https://doi.org/10.1007/s11306-021-01864-6
https://doi.org/10.1007/s11306-021-01864-6
Autor:
Meghan E. McLean, Maya R. MacLean, Hannah F. Cahill, Raj Pranap Arun, Olivia L. Walker, Marie-Claire D. Wasson, Wasundara Fernando, Jaganathan Venkatesh, Paola Marcato
Publikováno v:
Cancers. 15:492
Aldehyde dehydrogenase 1A3 (ALDH1A3) is one of 19 ALDH enzymes expressed in humans, and it is critical in the production of hormone receptor ligand retinoic acid (RA). We review the role of ALDH1A3 in normal physiology, its identification as a cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad0686e370dbe9414b0b0970956ef768
https://doi.org/10.3390/cancers15020492
https://doi.org/10.3390/cancers15020492
Autor:
Olivia L Walker, Justin M Brown, Cheryl A. Dean, Wasundara Fernando, Paola Marcato, Graham Dellaire, Brianne M. Cruickshank, Margaret L. Dahn, Marie-Claire D Wasson, Dejan Vidovic, Carter VanIderstine, Fiorella Morales-Quintanilla, Jaganathan Venkatesh
Publikováno v:
Cancers
Volume 13
Issue 11
Cancers, Vol 13, Iss 2644, p 2644 (2021)
Volume 13
Issue 11
Cancers, Vol 13, Iss 2644, p 2644 (2021)
Triple-negative breast cancers (TNBCs) are aggressive, lack targeted therapies and are enriched in cancer stem cells (CSCs). Novel therapies which target CSCs within these tumors would likely lead to improved outcomes for TNBC patients. Long non-codi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f1dc1f947ee5a04227318386f77ad3