Inferior temporal tau is associated with accelerated prospective cortical thinning in clinically normal older adults

Autor: Matthew R. Scott, Olivia L. Hampton, Rachel F. Buckley, Jasmeer P. Chhatwal, Bernard J. Hanseeuw, Heidi IL. Jacobs, Michael J. Properzi, Justin S. Sanchez, Keith A. Johnson, Reisa A. Sperling, Aaron P. Schultz

Publikováno v: NeuroImage, Vol 220, Iss , Pp 116991- (2020)

Neurofibrillary tau tangles are a hallmark pathology of Alzheimer's disease (AD) and are more closely associated with AD-related cortical atrophy and symptom severity than amyloid-beta (Aβ). However, studies regarding the effect of tau on longitudin

Externí odkaz: https://doaj.org/article/e277ebee1046491c8973965075c1da79

Harmonizing the preclinical Alzheimer cognitive composite for multicohort studies

Autor: Olivia L. Hampton, Shubhabrata Mukherjee, Michael J. Properzi, Aaron P. Schultz, Paul K. Crane, Laura E. Gibbons, Timothy J. Hohman, Paul Maruff, Yen Ying Lim, Rebecca E. Amariglio, Kathryn V. Papp, Keith A. Johnson, Dorene M. Rentz, Reisa A. Sperling, Rachel F. Buckley

Publikováno v: Neuropsychology.

Studies are increasingly examining research questions across multiple cohorts using data from the preclinical Alzheimer cognitive composite (PACC). Our objective was to use modern psychometric approaches to develop a harmonized PACC.We used longitudi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b146e13a7964a04aa330604bc2ff2a1
https://pubmed.ncbi.nlm.nih.gov/35862098

The combined influence of beta‐amyloid and vascular risk on prospective brain atrophy in clinically normal individuals

Autor: Jennifer S Rabin, Jeremy J Pruzin, Aaron P Schultz, Matthew R Scott, Olivia L Hampton, Stephanie Hsieh, Hyun‐Sik Yang, Wai‐Ying Yau, Trey Hedden, Dorene M Rentz, Keith A Johnson, Reisa A Sperling, Jasmeer P Chhatwal

Publikováno v: Alzheimer's & Dementia. 17

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80f37fcc4cfd597b8ce4b725c0e6d0de
https://doi.org/10.1002/alz.049730

Cortical thickness across the lifespan in a Colombian cohort with autosomal-dominant Alzheimer's disease: A cross-sectional study

Autor: Heidi I.L. Jacobs, Clara Vila-Castelar, Eric M. Reiman, Joshua T Fox-Fuller, Heirangi Torrico-Teave, Michael Brickhouse, Francisco Lopera, Sergio Alvarez, Cinthya Aguero, Edmarie Guzmán-Vélez, Justin S. Sanchez, Daniel Camilo Aguirre-Acevedo, Yinghua Chen, Reisa A. Sperling, Bradford C. Dickerson, Yi Su, Olivia L. Hampton, Yakeel T. Quiroz, Jairo Martínez, Martin Ochoa-Escudero, Keith A. Johnson, Ana Baena, Celina F Pluim, Federico d'Oleire Uquillas, Kewei Chen, Arabiye Artola

Publikováno v: Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 13(1):e12233. Elsevier BV
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)

Introduction Cortical thinning is a marker of neurodegeneration in Alzheimer's disease (AD). We investigated the age‐related trajectory of cortical thickness across the lifespan (9‐59 years) in a Colombian kindred with autosomal dominant AD (ADAD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbadb5a4543d7f5953f8cb6acd10c15c
https://pubmed.ncbi.nlm.nih.gov/34541287

Associations of peak width of skeletonized mean diffusivity with cardiovascular disease risk and cognitive decline in clinically normal older adults

Autor: Keith A. Johnson, Rachel F. Buckley, Olivia L. Hampton, Aaron P. Schultz, Heidi I.L. Jacobs, Bernard Hanseeuw, Matthew R. Scott, Jennifer S. Rabin, Jasmeer P. Chhatwal, Reisa A. Sperling, Michael J. Properzi, Hsiang-Chin Lori Chou

Publikováno v: Alzheimer's & Dementia. 16

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f98f66ad1a6fdc75fdfe77569033f94
https://doi.org/10.1002/alz.043812