Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Olivia L. Bordiuk"'
Autor:
Cendrine Tourette, Francesca Farina, Rafael P Vazquez-Manrique, Anne-Marie Orfila, Jessica Voisin, Sonia Hernandez, Nicolas Offner, J Alex Parker, Sophie Menet, Jinho Kim, Jungmok Lyu, Si Ho Choi, Kerry Cormier, Christina K Edgerly, Olivia L Bordiuk, Karen Smith, Anne Louise, Michael Halford, Steven Stacker, Jean-Philippe Vert, Robert J Ferrante, Wange Lu, Christian Neri
Publikováno v:
PLoS Biology, Vol 12, Iss 6, p e1001895 (2014)
The Wnt receptor Ryk is an evolutionary-conserved protein important during neuronal differentiation through several mechanisms, including γ-secretase cleavage and nuclear translocation of its intracellular domain (Ryk-ICD). Although the Wnt pathway
Externí odkaz:
https://doaj.org/article/30fe5f15c42b4abcbb453493275b5e19
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111453 (2014)
Neurogenesis, the formation of new neurons, can be observed in the adult brain of many mammalian species, including humans. Despite significant progress in our understanding of adult neurogenesis, we are still missing data about the extent and locati
Externí odkaz:
https://doaj.org/article/dcdea65ad9614366a0eaaba6314c71f5
Autor:
Wayne R. Matson, Christina K. Edgerly, Daniel J. Amante, Clemens R. Scherzer, Olivia L. Bordiuk, Steven M. Hersch, Karen M. Smith, Robert J. Ferrante, Samantha Matson, Jennifer P. Moody, Jinho Kim, H. Diana Rosas
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1802(7-8):673-681
A major goal of current clinical research in Huntington's disease (HD) has been to identify preclinical and manifest disease biomarkers, as these may improve both diagnosis and the power for therapeutic trials. Although the underlying biochemical alt
Autor:
Olivia L. Bordiuk, Nicolas Offner, Anne-Marie Orfila, Robert J. Ferrante, Rafael P. Vázquez-Manrique, Michael M. Halford, Jinho Kim, Christina K. Edgerly, Wange Lu, Cendrine Tourette, Karen M. Smith, Anne Louise, Sonia Hernandez, Kerry Cormier, Jean-Philippe Vert, Si Ho Choi, Jungmok Lyu, J. Alex Parker, Francesca Farina, Steven A. Stacker, Christian Neri, Sophie Menet, Jessica Voisin
Publikováno v:
PLoS Biology
PLoS Biology, Public Library of Science, 2014, 12 (6), pp.e1001895. ⟨10.1371/journal.pbio.1001895⟩
PLoS Biology, 2014, 12 (6), pp.e1001895. ⟨10.1371/journal.pbio.1001895⟩
PLoS Biology, Public Library of Science, 2014, 12 (6), pp.e1001895. 〈10.1371/journal.pbio.1001895〉
PLOS BIOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
PLoS Biology, Vol 12, Iss 6, p e1001895 (2014)
PLoS Biology, Public Library of Science, 2014, 12 (6), pp.e1001895. ⟨10.1371/journal.pbio.1001895⟩
PLoS Biology, 2014, 12 (6), pp.e1001895. ⟨10.1371/journal.pbio.1001895⟩
PLoS Biology, Public Library of Science, 2014, 12 (6), pp.e1001895. 〈10.1371/journal.pbio.1001895〉
PLOS BIOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
PLoS Biology, Vol 12, Iss 6, p e1001895 (2014)
A study of Huntington's disease reveals that neurons might fail to cope with maintaining their function during the pre-symptomatic, pathogenic phases of HD, possibly due to the early repression of key longevity-promoting transcription factors by abno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427bed9b6b241ccd95a774a759d7f997
https://hal.archives-ouvertes.fr/hal-01076146/file/journal.pbio.1001895-1.pdf
https://hal.archives-ouvertes.fr/hal-01076146/file/journal.pbio.1001895-1.pdf
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111453 (2014)
PLoS ONE
PLoS ONE
Neurogenesis, the formation of new neurons, can be observed in the adult brain of many mammalian species, including humans. Despite significant progress in our understanding of adult neurogenesis, we are still missing data about the extent and locati
Publikováno v:
International review of neurobiology. 98
Huntington's disease (HD) is an autosomal dominant, progressive, and fatal neurodegenerative disorder caused by an expanded polyglutamine cytosine-adenine-guanine repeat in the gene coding for the protein huntingtin. Despite great progress over the p
Huntington's disease (HD) is an autosomal dominant, progressive, and fatal neurodegenerative disorder caused by an expanded polyglutamine cytosine–adenine–guanine repeat in the gene coding for the protein huntingtin. Despite great progress over t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::442ecfb23c7810df1b5776d2640f5e9a
https://doi.org/10.1016/b978-0-12-381328-2.00016-x
https://doi.org/10.1016/b978-0-12-381328-2.00016-x
Autor:
Steven W. Jones, Andrew C Cooper, Jinho Kim, Karen L. Smith, Kerry Cormier, James R. Rusche, Samantha T Carreiro, Robert J. Ferrante, Olivia L. Bordiuk, Jennifer P. Moody, Ting Li, Christina K. Edgerly, Daniel J. Amante
Publikováno v:
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases. 11(6)
There is strong evidence from studies in humans and animal models to suggest the involvement of energy metabolism defects in neurodegenerative diseases. Uridine, a pyrimidine nucleoside, has been suggested to be neuroprotective in neurological disord
Autor:
SH Choi, S Menet, Rafael P. Vázquez-Manrique, Jinho Kim, Christina K. Edgerly, Cendrine Tourette, Wange Lu, Jessica Voisin, Anne-Marie Orfila, S Hernandez, J Lyu, Robert J. Ferrante, J. A. Parker, Jean-Philippe Vert, S Stacker, Francesca Farina, Olivia L. Bordiuk, Karen M. Smith, Christian Neri, K Cormier, Nicolas Offner, M Halford, Anne Louise
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 85:A15-A15
Background The ability of neurons to cope with the chronic stress induced by mutant protein expression in Huntington’s disease (HD) may determine the course of their decline and eventual demise. Although the pathophysiological importance of stress