Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Olivia L, Mooren"'
Publikováno v:
Cytoskeleton (Hoboken, N.J.)REFERENCES.
Septins in endothelial cells (ECs) have important roles supporting the integrity of the endothelial monolayer. Cell-cell junctions in EC monolayers are highly dynamic, with continuous retractions and protrusions. Depletion of septins in ECs leads to
Autor:
Suranjana Mukherjee, Joanna Kim, Olivia L Mooren, Stefanie T Shahan, Megan Cohan, John A Cooper
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118153 (2015)
Natural Killer (NK) cells perform many functions that depend on actin assembly, including adhesion, chemotaxis, lytic synapse assembly and cytolysis. HS1, the hematopoietic homolog of cortactin, binds to Arp2/3 complex and promotes actin assembly by
Externí odkaz:
https://doaj.org/article/b4353951dd954114a31f33f0dd170bf0
Autor:
Olivia L. Mooren, Timothy M. Lohman, Marlene Mekel, Patrick McConnell, John A. Cooper, Alexander G. Kozlov
Publikováno v:
Biochemistry
The heterodimeric actin capping protein (CP) is regulated by a set of proteins that contain CP-interacting (CPI) motifs. Outside of the CPI motif, the sequences of these proteins are unrelated and distinct. The CPI motif and surrounding sequences are
Autor:
Jiancheng Hu, Xinxin Wang, Jennifer L. Vella, Xiaolu Xu, Yunfeng Feng, Yina H. Huang, John A. Cooper, Sharon Celeste Morley, Elizabeth M. Todd, Olivia L. Mooren, Emily R. Jaeger
Publikováno v:
The Journal of Immunology. 197:1683-1691
Exploring the mechanisms controlling lymphocyte trafficking is essential for understanding the function of the immune system and the pathophysiology of immunodeficiencies. The mammalian Ste20–like kinase 1 (Mst1) has been identified as a critical s
Autor:
Olivia L. Mooren, John A. Cooper, Patrick I. McConnell, Marlene Mekel, Alexander G. Kozlov, Timothy M. Lohman
Publikováno v:
Biophysical Journal. 118:123a
Publikováno v:
Journal of Biological Chemistry. 290:18796-18805
Endothelial cells (ECs) form a monolayer that serves as a barrier between the blood and the underlying tissue. ECs tightly regulate their cell-cell junctions, controlling the passage of soluble materials and immune cells across the monolayer barrier.
Publikováno v:
Molecular Biology of the Cell
Actin assembly downstream of WAVE2 in endothelial cells is necessary to engage transmigrating lymphocytes, promote the transcellular route of migration, and close junctional pores after the lymphocyte moves away. In addition, WAVE2 is necessary for e
Autor:
Stefanie T. Shahan, Jinmei Li, Suranjana Mukherjee, John A. Cooper, Olivia L. Mooren, Michael D. Onken
Publikováno v:
Cytoskeleton. 71:695-706
Endothelial cells (ECs) line the microvasculature and constitute a barrier between the vessel lumen and surrounding tissues. ECs inform circulating immune cells of the health and integrity of surrounding tissues, recruiting them in response to pathog
Publikováno v:
Annual Review of Biochemistry. 81:661-686
Endocytosis includes a number of processes by which cells internalize segments of their plasma membrane, enclosing a wide variety of material from outside the cell. Endocytosis can contribute to uptake of nutrients, regulation of signaling molecules,
Publikováno v:
Current Opinion in Biotechnology. 21:604-610
Tight regulation of the actin cytoskeleton is critical for many cell functions, including various forms of cellular uptake. Clathrin-mediated endocytosis (CME) is one of the main methods of uptake in many cell types. An intact and properly regulated